CACNB2

Calcium channel, voltage-dependent, beta 2 subunit
File:PBB Protein CACNB2 image.jpg PDB rendering based on 1t0h.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1t0h​, 1t0j​
Identifiers
Symbols	CACNB2 ; CACNLB2; FLJ23743; MYSB
External IDs	Template:OMIM5 Template:MGI HomoloGene: 75191
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Calcium channel, voltage-dependent, beta 2 subunit, also known as CACNB2, is a human gene.

See also

• Voltage-dependent calcium channel

Further reading

• Williams ME, Feldman DH, McCue AF; et al. (1992). "Structure and functional expression of alpha 1, alpha 2, and beta subunits of a novel human neuronal calcium channel subtype". Neuron. 8 (1): 71–84. PMID 1309651.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brust PF, Simerson S, McCue AF; et al. (1994). "Human neuronal voltage-dependent calcium channels: studies on subunit structure and role in channel assembly". Neuropharmacology. 32 (11): 1089–102. PMID 8107964.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rosenfeld MR, Wong E, Dalmau J; et al. (1993). "Cloning and characterization of a Lambert-Eaton myasthenic syndrome antigen". Ann. Neurol. 33 (1): 113–20. doi:10.1002/ana.410330126. PMID 8494331.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hillier LD, Lennon G, Becker M; et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. PMID 8889549.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Volsen SG, Day NC, McCormack AL; et al. (1997). "The expression of voltage-dependent calcium channel beta subunits in human cerebellum". Neuroscience. 80 (1): 161–74. PMID 9252229.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Taviaux S, Williams ME, Harpold MM; et al. (1997). "Assignment of human genes for beta 2 and beta 4 subunits of voltage-dependent Ca2+ channels to chromosomes 10p12 and 2q22-q23". Hum. Genet. 100 (2): 151–4. PMID 9254841.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Robertson HM, Zumpano KL (1998). "Molecular evolution of an ancient mariner transposon, Hsmar1, in the human genome". Gene. 205 (1–2): 203–17. PMID 9461395.
• Allen TJ, Mikala G (1998). "Effects of temperature on human L-type cardiac Ca2+ channels expressed in Xenopus oocytes". Pflugers Arch. 436 (2): 238–47. PMID 9594024.
• Day NC, Volsen SG, McCormack AL; et al. (1998). "The expression of voltage-dependent calcium channel beta subunits in human hippocampus". Brain Res. Mol. Brain Res. 60 (2): 259–69. PMID 9757060.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brice NL, Dolphin AC (1999). "Differential plasma membrane targeting of voltage-dependent calcium channel subunits expressed in a polarized epithelial cell line". J. Physiol. (Lond.). 515 ( Pt 3): 685–94. PMID 10066897.
• Gerhardstein BL, Puri TS, Chien AJ, Hosey MM (1999). "Identification of the sites phosphorylated by cyclic AMP-dependent protein kinase on the beta 2 subunit of L-type voltage-dependent calcium channels". Biochemistry. 38 (32): 10361–70. doi:10.1021/bi990896o. PMID 10441130.CS1 maint: Multiple names: authors list (link)
• Lie AA, Blümcke I, Volsen SG; et al. (1999). "Distribution of voltage-dependent calcium channel beta subunits in the hippocampus of patients with temporal lobe epilepsy". Neuroscience. 93 (2): 449–56. PMID 10465427.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bünemann M, Gerhardstein BL, Gao T, Hosey MM (1999). "Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the beta(2) subunit". J. Biol. Chem. 274 (48): 33851–4. PMID 10567342.CS1 maint: Multiple names: authors list (link)
• Yamaguchi H, Okuda M, Mikala G; et al. (2000). "Cloning of the beta(2a) subunit of the voltage-dependent calcium channel from human heart: cooperative effect of alpha(2)/delta and beta(2a) on the membrane expression of the alpha(1C) subunit". Biochem. Biophys. Res. Commun. 267 (1): 156–63. doi:10.1006/bbrc.1999.1926. PMID 10623591.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Colecraft HM, Alseikhan B, Takahashi SX; et al. (2002). "Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells". J. Physiol. (Lond.). 541 (Pt 2): 435–52. PMID 12042350.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Takahashi SX, Mittman S, Colecraft HM (2004). "Distinctive modulatory effects of five human auxiliary beta2 subunit splice variants on L-type calcium channel gating". Biophys. J. 84 (5): 3007–21. PMID 12719232.CS1 maint: Multiple names: authors list (link)
• Finlin BS, Crump SM, Satin J, Andres DA (2004). "Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases". Proc. Natl. Acad. Sci. U.S.A. 100 (24): 14469–74. doi:10.1073/pnas.2437756100. PMID 14623965.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Foell JD, Balijepalli RC, Delisle BP; et al. (2004). "Molecular heterogeneity of calcium channel beta-subunits in canine and human heart: evidence for differential subcellular localization". Physiol. Genomics. 17 (2): 183–200. doi:10.1152/physiolgenomics.00207.2003. PMID 14762176.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Harry JB, Kobrinsky E, Abernethy DR, Soldatov NM (2004). "New short splice variants of the human cardiac Cavbeta2 subunit: redefining the major functional motifs implemented in modulation of the Cav1.2 channel". J. Biol. Chem. 279 (45): 46367–72. doi:10.1074/jbc.M409523200. PMID 15339916.CS1 maint: Multiple names: authors list (link)

External links

• CACNB2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)