TRPM2

Transient receptor potential cation channel, subfamily M, member 2
Identifiers
Symbols	TRPM2 ; EREG1; KNP3; LTRPC2; MGC133383; NUDT9H; NUDT9L1; TRPC7
External IDs	Template:OMIM5 Template:MGI HomoloGene: 20709
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE TRPM2 205708 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Transient receptor potential cation channel, subfamily M, member 2, also known as TRPM2, is a human gene.

The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

See also

• TRPM

Further reading

• Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100.CS1 maint: Multiple names: authors list (link)
• Eisfeld J, Lückhoff A (2007). "TRPM2". Handb Exp Pharmacol (179): 237–52. doi:10.1007/978-3-540-34891-7_14. PMID 17217061.

External links

• TRPM2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.