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{{Infobox_gene}}
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'''Glycoprotein IX (platelet)''' ('''GP9''') also known as '''CD42a''' ('''C'''luster of '''D'''ifferentiation '''42a'''), is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GP9 glycoprotein IX (platelet)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2815| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Glycoprotein IX (platelet)
| HGNCid = 4444
| Symbol = GP9
| AltSymbols =; CD42a; GPIX
| OMIM = 173515
| ECnumber = 
| Homologene = 144
| MGIid = 1860137
| GeneAtlas_image1 = PBB_GE_GP9_206883_x_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}}
| Process = {{GNF_GO|id=GO:0007155 |text = cell adhesion}} {{GNF_GO|id=GO:0007596 |text = blood coagulation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 2815
    | Hs_Ensembl = ENSG00000169704
    | Hs_RefseqProtein = NP_000165
    | Hs_RefseqmRNA = NM_000174
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 3
    | Hs_GenLoc_start = 130262300
    | Hs_GenLoc_end = 130263941
    | Hs_Uniprot = P14770
    | Mm_EntrezGene = 54368
    | Mm_Ensembl = ENSMUSG00000030054
    | Mm_RefseqmRNA = NM_018762
    | Mm_RefseqProtein = NP_061232
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 87743777
    | Mm_GenLoc_end = 87745403
    | Mm_Uniprot = 
  }}
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'''Glycoprotein IX (platelet)''' ('''GP9''') also known as '''CD42a''' ('''C'''luster of '''D'''ifferentiation '''42a'''), is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GP9 glycoprotein IX (platelet)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2815| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = Platelet glycoprotein IX (GP9) is a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib (GP Ib), a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor (VWF; MIM 193400). The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with GP9 and platelet glycoprotein V (GP5; MIM 173511).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: GP9 glycoprotein IX (platelet)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2815| accessdate = }}</ref>
| summary_text = Platelet glycoprotein IX (GP9) is a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with [[glycoprotein Ib]] (GP Ib), a platelet surface membrane glycoprotein complex that functions as a receptor for [[von Willebrand factor]] (VWF; MIM 193400) (known as the [[Glycoprotein Ib-IX-V Receptor Complex]]). The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with GP9 and platelet [[GP5|glycoprotein V]] (GP5; MIM 173511).[supplied by OMIM]<ref name="entrez" />
}}
}}


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==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
Line 64: Line 18:
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Kunishima S, Kamiya T, Saito H |title=Genetic abnormalities of Bernard-Soulier syndrome. |journal=Int. J. Hematol. |volume=76 |issue= 4 |pages= 319-27 |year= 2003 |pmid= 12463594 |doi=  }}
*{{cite journal  |vauthors=Kunishima S, Kamiya T, Saito H |title=Genetic abnormalities of Bernard-Soulier syndrome |journal=Int. J. Hematol. |volume=76 |issue= 4 |pages= 319–27 |year= 2003 |pmid= 12463594 |doi=10.1007/BF02982690 }}
*{{cite journal  | author=Hickey MJ, Deaven LL, Roth GJ |title=Human platelet glycoprotein IX. Characterization of cDNA and localization of the gene to chromosome 3. |journal=FEBS Lett. |volume=274 |issue= 1-2 |pages= 189-92 |year= 1991 |pmid= 2253772 |doi=  }}
*{{cite journal  |vauthors=Hickey MJ, Deaven LL, Roth GJ |title=Human platelet glycoprotein IX. Characterization of cDNA and localization of the gene to chromosome 3 |journal=FEBS Lett. |volume=274 |issue= 1–2 |pages= 189–92 |year= 1991 |pmid= 2253772 |doi=10.1016/0014-5793(90)81361-Q }}
*{{cite journal | author=Du X, Beutler L, Ruan C, ''et al.'' |title=Glycoprotein Ib and glycoprotein IX are fully complexed in the intact platelet membrane. |journal=Blood |volume=69 |issue= 5 |pages= 1524-7 |year= 1987 |pmid= 2436691 |doi=  }}
*{{cite journal   |vauthors=Du X, Beutler L, Ruan C, etal |title=Glycoprotein Ib and glycoprotein IX are fully complexed in the intact platelet membrane |journal=Blood |volume=69 |issue= 5 |pages= 1524–7 |year= 1987 |pmid= 2436691 |doi=  }}
*{{cite journal | author=Andrews RK, Booth WJ, Gorman JJ, ''et al.'' |title=Purification of botrocetin from Bothrops jararaca venom. Analysis of the botrocetin-mediated interaction between von Willebrand factor and the human platelet membrane glycoprotein Ib-IX complex. |journal=Biochemistry |volume=28 |issue= 21 |pages= 8317-26 |year= 1990 |pmid= 2557900 |doi=  }}
*{{cite journal   |vauthors=Andrews RK, Booth WJ, Gorman JJ, etal |title=Purification of botrocetin from Bothrops jararaca venom. Analysis of the botrocetin-mediated interaction between von Willebrand factor and the human platelet membrane glycoprotein Ib-IX complex |journal=Biochemistry |volume=28 |issue= 21 |pages= 8317–26 |year= 1990 |pmid= 2557900 |doi=10.1021/bi00447a009 }}
*{{cite journal  | author=Hickey MJ, Williams SA, Roth GJ |title=Human platelet glycoprotein IX: an adhesive prototype of leucine-rich glycoproteins with flank-center-flank structures. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=86 |issue= 17 |pages= 6773-7 |year= 1989 |pmid= 2771955 |doi=  }}
*{{cite journal  |vauthors=Hickey MJ, Williams SA, Roth GJ |title=Human platelet glycoprotein IX: an adhesive prototype of leucine-rich glycoproteins with flank-center-flank structures |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=86 |issue= 17 |pages= 6773–7 |year= 1989 |pmid= 2771955 |doi=10.1073/pnas.86.17.6773  | pmc=297928 }}
*{{cite journal  | author=Roth GJ, Ozols J, Nugent DJ, Williams SA |title=Isolation and characterization of human platelet glycoprotein IX. |journal=Biochem. Biophys. Res. Commun. |volume=156 |issue= 2 |pages= 931-9 |year= 1988 |pmid= 3056407 |doi=  }}
*{{cite journal  |vauthors=Roth GJ, Ozols J, Nugent DJ, Williams SA |title=Isolation and characterization of human platelet glycoprotein IX |journal=Biochem. Biophys. Res. Commun. |volume=156 |issue= 2 |pages= 931–9 |year= 1988 |pmid= 3056407 |doi=10.1016/S0006-291X(88)80933-1 }}
*{{cite journal  | author=Meyer SC, Fox JE |title=Interaction of platelet glycoprotein V with glycoprotein Ib-IX regulates expression of the glycoproteins and binding of von Willebrand factor to glycoprotein Ib-IX in transfected cells. |journal=J. Biol. Chem. |volume=270 |issue= 24 |pages= 14693-9 |year= 1995 |pmid= 7782333 |doi=  }}
*{{cite journal  |vauthors=Meyer SC, Fox JE |title=Interaction of platelet glycoprotein V with glycoprotein Ib-IX regulates expression of the glycoproteins and binding of von Willebrand factor to glycoprotein Ib-IX in transfected cells |journal=J. Biol. Chem. |volume=270 |issue= 24 |pages= 14693–9 |year= 1995 |pmid= 7782333 |doi=10.1074/jbc.270.24.14693 }}
*{{cite journal  | author=Clemetson JM, Kyrle PA, Brenner B, Clemetson KJ |title=Variant Bernard-Soulier syndrome associated with a homozygous mutation in the leucine-rich domain of glycoprotein IX. |journal=Blood |volume=84 |issue= 4 |pages= 1124-31 |year= 1994 |pmid= 8049428 |doi=  }}
*{{cite journal  |vauthors=Clemetson JM, Kyrle PA, Brenner B, Clemetson KJ |title=Variant Bernard-Soulier syndrome associated with a homozygous mutation in the leucine-rich domain of glycoprotein IX |journal=Blood |volume=84 |issue= 4 |pages= 1124–31 |year= 1994 |pmid= 8049428 |doi=  }}
*{{cite journal  | author=Hickey MJ, Roth GJ |title=Characterization of the gene encoding human platelet glycoprotein IX. |journal=J. Biol. Chem. |volume=268 |issue= 5 |pages= 3438-43 |year= 1993 |pmid= 8429020 |doi=  }}
*{{cite journal  |vauthors=Hickey MJ, Roth GJ |title=Characterization of the gene encoding human platelet glycoprotein IX |journal=J. Biol. Chem. |volume=268 |issue= 5 |pages= 3438–43 |year= 1993 |pmid= 8429020 |doi=  }}
*{{cite journal | author=Wright SD, Michaelides K, Johnson DJ, ''et al.'' |title=Double heterozygosity for mutations in the platelet glycoprotein IX gene in three siblings with Bernard-Soulier syndrome. |journal=Blood |volume=81 |issue= 9 |pages= 2339-47 |year= 1993 |pmid= 8481514 |doi=  }}
*{{cite journal   |vauthors=Wright SD, Michaelides K, Johnson DJ, etal |title=Double heterozygosity for mutations in the platelet glycoprotein IX gene in three siblings with Bernard-Soulier syndrome |journal=Blood |volume=81 |issue= 9 |pages= 2339–47 |year= 1993 |pmid= 8481514 |doi=  }}
*{{cite journal  | author=Berger G, Massé JM, Cramer EM |title=Alpha-granule membrane mirrors the platelet plasma membrane and contains the glycoproteins Ib, IX, and V. |journal=Blood |volume=87 |issue= 4 |pages= 1385-95 |year= 1996 |pmid= 8608228 |doi=  }}
*{{cite journal  |vauthors=Berger G, Massé JM, Cramer EM |title=Alpha-granule membrane mirrors the platelet plasma membrane and contains the glycoproteins Ib, IX, and V |journal=Blood |volume=87 |issue= 4 |pages= 1385–95 |year= 1996 |pmid= 8608228 |doi=  }}
*{{cite journal | author=Hollmann C, Haag F, Schlott M, ''et al.'' |title=Molecular characterization of mouse T-cell ecto-ADP-ribosyltransferase Rt6: cloning of a second functional gene and identification of the Rt6 gene products. |journal=Mol. Immunol. |volume=33 |issue= 9 |pages= 807-17 |year= 1996 |pmid= 8811076 |doi=  }}
*{{cite journal   |vauthors=Hollmann C, Haag F, Schlott M, etal |title=Molecular characterization of mouse T-cell ecto-ADP-ribosyltransferase Rt6: cloning of a second functional gene and identification of the Rt6 gene products |journal=Mol. Immunol. |volume=33 |issue= 9 |pages= 807–17 |year= 1996 |pmid= 8811076 |doi=10.1016/0161-5890(96)00008-9 }}
*{{cite journal  | author=Noris P, Simsek S, Stibbe J, von dem Borne AE |title=A phenylalanine-55 to serine amino-acid substitution in the human glycoprotein IX leucine-rich repeat is associated with Bernard-Soulier syndrome. |journal=Br. J. Haematol. |volume=97 |issue= 2 |pages= 312-20 |year= 1997 |pmid= 9163595 |doi=  }}
*{{cite journal  |vauthors=Noris P, Simsek S, Stibbe J, von dem Borne AE |title=A phenylalanine-55 to serine amino-acid substitution in the human glycoprotein IX leucine-rich repeat is associated with Bernard-Soulier syndrome |journal=Br. J. Haematol. |volume=97 |issue= 2 |pages= 312–20 |year= 1997 |pmid= 9163595 |doi=10.1046/j.1365-2141.1997.582706.x }}
*{{cite journal | author=Hayashi T, Suzuki K, Yahagi A, ''et al.'' |title=Corrected DNA sequence of the platelet glycoprotein IX gene. |journal=Thromb. Haemost. |volume=77 |issue= 5 |pages= 1034-5 |year= 1997 |pmid= 9184424 |doi=  }}
*{{cite journal   |vauthors=Hayashi T, Suzuki K, Yahagi A, etal |title=Corrected DNA sequence of the platelet glycoprotein IX gene |journal=Thromb. Haemost. |volume=77 |issue= 5 |pages= 1034–5 |year= 1997 |pmid= 9184424 |doi=  }}
*{{cite journal | author=Bradford HN, Dela Cadena RA, Kunapuli SP, ''et al.'' |title=Human kininogens regulate thrombin binding to platelets through the glycoprotein Ib-IX-V complex. |journal=Blood |volume=90 |issue= 4 |pages= 1508-15 |year= 1997 |pmid= 9269768 |doi=  }}
*{{cite journal   |vauthors=Bradford HN, Dela Cadena RA, Kunapuli SP, etal |title=Human kininogens regulate thrombin binding to platelets through the glycoprotein Ib-IX-V complex |journal=Blood |volume=90 |issue= 4 |pages= 1508–15 |year= 1997 |pmid= 9269768 |doi=  }}
*{{cite journal | author=Suzuki K, Hayashi T, Yahagi A, ''et al.'' |title=Novel point mutation in the leucine-rich motif of the platelet glycoprotein IX associated with Bernard-Soulier syndrome. |journal=Br. J. Haematol. |volume=99 |issue= 4 |pages= 794-800 |year= 1998 |pmid= 9432024 |doi=  }}
*{{cite journal   |vauthors=Suzuki K, Hayashi T, Yahagi A, etal |title=Novel point mutation in the leucine-rich motif of the platelet glycoprotein IX associated with Bernard-Soulier syndrome |journal=Br. J. Haematol. |volume=99 |issue= 4 |pages= 794–800 |year= 1998 |pmid= 9432024 |doi=10.1046/j.1365-2141.1997.4753275.x }}
*{{cite journal | author=Noris P, Arbustini E, Spedini P, ''et al.'' |title=A new variant of Bernard-Soulier syndrome characterized by dysfunctional glycoprotein (GP) Ib and severely reduced amounts of GPIX and GPV. |journal=Br. J. Haematol. |volume=103 |issue= 4 |pages= 1004-13 |year= 1999 |pmid= 9886312 |doi= }}
*{{cite journal   |vauthors=Noris P, Arbustini E, Spedini P, etal |title=A new variant of Bernard-Soulier syndrome characterized by dysfunctional glycoprotein (GP) Ib and severely reduced amounts of GPIX and GPV |journal=Br. J. Haematol. |volume=103 |issue= 4 |pages= 1004–13 |year= 1999 |pmid= 9886312 |doi=10.1046/j.1365-2141.1998.01100.x  }}
*{{cite journal  | author=Longhurst CM, White MM, Wilkinson DA, Jennings LK |title=A CD9, alphaIIbbeta3, integrin-associated protein, and GPIb/V/IX complex on the surface of human platelets is influenced by alphaIIbbeta3 conformational states. |journal=Eur. J. Biochem. |volume=263 |issue= 1 |pages= 104-11 |year= 1999 |pmid= 10429193 |doi=  }}
*{{cite journal  |vauthors=Longhurst CM, White MM, Wilkinson DA, Jennings LK |title=A CD9, alphaIIbbeta3, integrin-associated protein, and GPIb/V/IX complex on the surface of human platelets is influenced by alphaIIbbeta3 conformational states |journal=Eur. J. Biochem. |volume=263 |issue= 1 |pages= 104–11 |year= 1999 |pmid= 10429193 |doi=10.1046/j.1432-1327.1999.00467.x }}
*{{cite journal | author=Kunishima S, Tomiyama Y, Honda S, ''et al.'' |title=Cys97-->Tyr mutation in the glycoprotein IX gene associated with Bernard-Soulier syndrome. |journal=Br. J. Haematol. |volume=107 |issue= 3 |pages= 539-45 |year= 2000 |pmid= 10583255 |doi=  }}
*{{cite journal   |vauthors=Kunishima S, Tomiyama Y, Honda S, etal |title=Cys97-->Tyr mutation in the glycoprotein IX gene associated with Bernard-Soulier syndrome |journal=Br. J. Haematol. |volume=107 |issue= 3 |pages= 539–45 |year= 2000 |pmid= 10583255 |doi=10.1046/j.1365-2141.1999.01733.x }}
*{{cite journal | author=Rivera CE, Villagra J, Riordan M, ''et al.'' |title=Identification of a new mutation in platelet glycoprotein IX (GPIX) in a patient with Bernard-Soulier syndrome. |journal=Br. J. Haematol. |volume=112 |issue= 1 |pages= 105-8 |year= 2001 |pmid= 11167791 |doi=  }}
*{{cite journal   |vauthors=Rivera CE, Villagra J, Riordan M, etal |title=Identification of a new mutation in platelet glycoprotein IX (GPIX) in a patient with Bernard-Soulier syndrome |journal=Br. J. Haematol. |volume=112 |issue= 1 |pages= 105–8 |year= 2001 |pmid= 11167791 |doi=10.1046/j.1365-2141.2001.02529.x }}
}}
}}
{{refend}}
{{refend}}
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* {{MeshName|GP9+protein,+human}}
* {{MeshName|GP9+protein,+human}}


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Latest revision as of 01:50, 27 October 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Glycoprotein IX (platelet) (GP9) also known as CD42a (Cluster of Differentiation 42a), is a human gene.[1]

Platelet glycoprotein IX (GP9) is a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib (GP Ib), a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor (VWF; MIM 193400) (known as the Glycoprotein Ib-IX-V Receptor Complex). The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with GP9 and platelet glycoprotein V (GP5; MIM 173511).[supplied by OMIM][1]

See also

References

  1. ↑ 1.0 1.1 "Entrez Gene: GP9 glycoprotein IX (platelet)".

Further reading

  • Kunishima S, Kamiya T, Saito H (2003). "Genetic abnormalities of Bernard-Soulier syndrome". Int. J. Hematol. 76 (4): 319–27. doi:10.1007/BF02982690. PMID 12463594.
  • Hickey MJ, Deaven LL, Roth GJ (1991). "Human platelet glycoprotein IX. Characterization of cDNA and localization of the gene to chromosome 3". FEBS Lett. 274 (1–2): 189–92. doi:10.1016/0014-5793(90)81361-Q. PMID 2253772.
  • Du X, Beutler L, Ruan C, et al. (1987). "Glycoprotein Ib and glycoprotein IX are fully complexed in the intact platelet membrane". Blood. 69 (5): 1524–7. PMID 2436691.
  • Andrews RK, Booth WJ, Gorman JJ, et al. (1990). "Purification of botrocetin from Bothrops jararaca venom. Analysis of the botrocetin-mediated interaction between von Willebrand factor and the human platelet membrane glycoprotein Ib-IX complex". Biochemistry. 28 (21): 8317–26. doi:10.1021/bi00447a009. PMID 2557900.
  • Hickey MJ, Williams SA, Roth GJ (1989). "Human platelet glycoprotein IX: an adhesive prototype of leucine-rich glycoproteins with flank-center-flank structures". Proc. Natl. Acad. Sci. U.S.A. 86 (17): 6773–7. doi:10.1073/pnas.86.17.6773. PMC 297928. PMID 2771955.
  • Roth GJ, Ozols J, Nugent DJ, Williams SA (1988). "Isolation and characterization of human platelet glycoprotein IX". Biochem. Biophys. Res. Commun. 156 (2): 931–9. doi:10.1016/S0006-291X(88)80933-1. PMID 3056407.
  • Meyer SC, Fox JE (1995). "Interaction of platelet glycoprotein V with glycoprotein Ib-IX regulates expression of the glycoproteins and binding of von Willebrand factor to glycoprotein Ib-IX in transfected cells". J. Biol. Chem. 270 (24): 14693–9. doi:10.1074/jbc.270.24.14693. PMID 7782333.
  • Clemetson JM, Kyrle PA, Brenner B, Clemetson KJ (1994). "Variant Bernard-Soulier syndrome associated with a homozygous mutation in the leucine-rich domain of glycoprotein IX". Blood. 84 (4): 1124–31. PMID 8049428.
  • Hickey MJ, Roth GJ (1993). "Characterization of the gene encoding human platelet glycoprotein IX". J. Biol. Chem. 268 (5): 3438–43. PMID 8429020.
  • Wright SD, Michaelides K, Johnson DJ, et al. (1993). "Double heterozygosity for mutations in the platelet glycoprotein IX gene in three siblings with Bernard-Soulier syndrome". Blood. 81 (9): 2339–47. PMID 8481514.
  • Berger G, Massé JM, Cramer EM (1996). "Alpha-granule membrane mirrors the platelet plasma membrane and contains the glycoproteins Ib, IX, and V". Blood. 87 (4): 1385–95. PMID 8608228.
  • Hollmann C, Haag F, Schlott M, et al. (1996). "Molecular characterization of mouse T-cell ecto-ADP-ribosyltransferase Rt6: cloning of a second functional gene and identification of the Rt6 gene products". Mol. Immunol. 33 (9): 807–17. doi:10.1016/0161-5890(96)00008-9. PMID 8811076.
  • Noris P, Simsek S, Stibbe J, von dem Borne AE (1997). "A phenylalanine-55 to serine amino-acid substitution in the human glycoprotein IX leucine-rich repeat is associated with Bernard-Soulier syndrome". Br. J. Haematol. 97 (2): 312–20. doi:10.1046/j.1365-2141.1997.582706.x. PMID 9163595.
  • Hayashi T, Suzuki K, Yahagi A, et al. (1997). "Corrected DNA sequence of the platelet glycoprotein IX gene". Thromb. Haemost. 77 (5): 1034–5. PMID 9184424.
  • Bradford HN, Dela Cadena RA, Kunapuli SP, et al. (1997). "Human kininogens regulate thrombin binding to platelets through the glycoprotein Ib-IX-V complex". Blood. 90 (4): 1508–15. PMID 9269768.
  • Suzuki K, Hayashi T, Yahagi A, et al. (1998). "Novel point mutation in the leucine-rich motif of the platelet glycoprotein IX associated with Bernard-Soulier syndrome". Br. J. Haematol. 99 (4): 794–800. doi:10.1046/j.1365-2141.1997.4753275.x. PMID 9432024.
  • Noris P, Arbustini E, Spedini P, et al. (1999). "A new variant of Bernard-Soulier syndrome characterized by dysfunctional glycoprotein (GP) Ib and severely reduced amounts of GPIX and GPV". Br. J. Haematol. 103 (4): 1004–13. doi:10.1046/j.1365-2141.1998.01100.x. PMID 9886312.
  • Longhurst CM, White MM, Wilkinson DA, Jennings LK (1999). "A CD9, alphaIIbbeta3, integrin-associated protein, and GPIb/V/IX complex on the surface of human platelets is influenced by alphaIIbbeta3 conformational states". Eur. J. Biochem. 263 (1): 104–11. doi:10.1046/j.1432-1327.1999.00467.x. PMID 10429193.
  • Kunishima S, Tomiyama Y, Honda S, et al. (2000). "Cys97-->Tyr mutation in the glycoprotein IX gene associated with Bernard-Soulier syndrome". Br. J. Haematol. 107 (3): 539–45. doi:10.1046/j.1365-2141.1999.01733.x. PMID 10583255.
  • Rivera CE, Villagra J, Riordan M, et al. (2001). "Identification of a new mutation in platelet glycoprotein IX (GPIX) in a patient with Bernard-Soulier syndrome". Br. J. Haematol. 112 (1): 105–8. doi:10.1046/j.1365-2141.2001.02529.x. PMID 11167791.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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