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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''CD83''' (Cluster of Differentiation 83) is a human [[protein]] encoded by the {{gene|CD83}} [[gene]].<ref>{{cite web | title = Entrez Gene: CD83 CD83 molecule| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9308| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== See also ==
{{GNF_Protein_box
* [[Cluster of differentiation]]
| image =
| image_source =
| PDB =
| Name = CD83 molecule
| HGNCid = 1703
| Symbol = CD83
| AltSymbols =; BL11; HB15
| OMIM = 604534
| ECnumber = 
| Homologene = 3121
| MGIid = 1328316
| GeneAtlas_image1 = PBB_GE_CD83_204440_at_tn.png
| Function =
| Component = {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}}
| Process = {{GNF_GO|id=GO:0006952 |text = defense response}} {{GNF_GO|id=GO:0006959 |text = humoral immune response}} {{GNF_GO|id=GO:0007165 |text = signal transduction}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9308
    | Hs_Ensembl = ENSG00000112149
    | Hs_RefseqProtein = NP_001035370
    | Hs_RefseqmRNA = NM_001040280
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 6
    | Hs_GenLoc_start = 14225715
    | Hs_GenLoc_end = 14245063
    | Hs_Uniprot = Q01151
    | Mm_EntrezGene = 12522
    | Mm_Ensembl = ENSMUSG00000015396
    | Mm_RefseqmRNA = NM_009856
    | Mm_RefseqProtein = NP_033986
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 13
    | Mm_GenLoc_start = 43796157
    | Mm_GenLoc_end = 43814102
    | Mm_Uniprot = 
  }}
}}


'''CD83''' (Cluster of Differentiation 83) is a human [[protein]] encoded by the {{gene|CD83}} [[gene]].<ref>{{cite web | title = Entrez Gene: CD83 CD83 molecule| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9308| accessdate = }}</ref>
== References ==
{{reflist}}


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Further reading ==
{{PBB_Summary
{{refbegin | 2}}
| section_title =  
* {{cite journal | vauthors = Lechmann M, Berchtold S, Hauber J, Steinkasserer A | title = CD83 on dendritic cells: more than just a marker for maturation. | journal = Trends Immunol. | volume = 23 | issue = 6 | pages = 273–5 | year = 2002 | pmid = 12072358 | doi = 10.1016/S1471-4906(02)02214-7 }}
| summary_text =  
* {{cite journal | vauthors = Zhou LJ, Schwarting R, Smith HM, Tedder TF | title = A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily. | journal = J. Immunol. | volume = 149 | issue = 2 | pages = 735–42 | year = 1992 | pmid = 1378080 | doi =  }}
}}
* {{cite journal | vauthors = Zhou LJ, Tedder TF | title = Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. | journal = J. Immunol. | volume = 154 | issue = 8 | pages = 3821–35 | year = 1995 | pmid = 7706722 | doi = }}
* {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | year = 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
* {{cite journal | vauthors = Kozlow EJ, Wilson GL, Fox CH, Kehrl JH | title = Subtractive cDNA cloning of a novel member of the Ig gene superfamily expressed at high levels in activated B lymphocytes | journal = Blood | volume = 81 | issue = 2 | pages = 454–61 | year = 1993 | pmid = 8422464 | doi =  }}
* {{cite journal | vauthors = de la Fuente MA, Pizcueta P, Nadal M, Bosch J, Engel P | title = CD84 leukocyte antigen is a new member of the Ig superfamily | journal = Blood | volume = 90 | issue = 6 | pages = 2398–405 | year = 1997 | pmid = 9310491 | doi =  }}
* {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | year = 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
* {{cite journal | vauthors = Olavesen MG, Bentley E, Mason RV, Stephens RJ, Ragoussis J | title = Fine mapping of 39 ESTs on human chromosome 6p23-p25 | journal = Genomics | volume = 46 | issue = 2 | pages = 303–6 | year = 1998 | pmid = 9417921 | doi = 10.1006/geno.1997.5032 }}
* {{cite journal | vauthors = Twist CJ, Beier DR, Disteche CM, Edelhoff S, Tedder TF | title = The mouse Cd83 gene: structure, domain organization, and chromosome localization | journal = Immunogenetics | volume = 48 | issue = 6 | pages = 383–93 | year = 1998 | pmid = 9799334 | doi = 10.1007/s002510050449 }}
* {{cite journal | vauthors = Berchtold S, Mühl-Zürbes P, Heufler C, Winklehner P, Schuler G, Steinkasserer A | title = Cloning, recombinant expression and biochemical characterization of the murine CD83 molecule which is specifically upregulated during dendritic cell maturation | journal = FEBS Lett. | volume = 461 | issue = 3 | pages = 211–6 | year = 1999 | pmid = 10567699 | doi = 10.1016/S0014-5793(99)01465-9 }}
* {{cite journal | vauthors = Scholler N, Hayden-Ledbetter M, Hellström KE, Hellström I, Ledbetter JA | title = CD83 is a sialic acid-binding Ig-like lectin (Siglec) adhesion receptor that binds monocytes and a subset of activated CD8+ T cells | journal = J. Immunol. | volume = 166 | issue = 6 | pages = 3865–72 | year = 2001 | pmid = 11238630 | doi = 10.4049/jimmunol.166.6.3865 }}
* {{cite journal | vauthors = Fanales-Belasio E, Moretti S, Nappi F, Barillari G, Micheletti F, Cafaro A, Ensoli B | title = Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses | journal = J. Immunol. | volume = 168 | issue = 1 | pages = 197–206 | year = 2002 | pmid = 11751963 | doi = 10.4049/jimmunol.168.1.197 }}
* {{cite journal | vauthors = Berchtold S, Mühl-Zürbes P, Maczek E, Golka A, Schuler G, Steinkasserer A | title = Cloning and characterization of the promoter region of the human CD83 gene | journal = Immunobiology | volume = 205 | issue = 3 | pages = 231–46 | year = 2003 | pmid = 12182451 | doi = 10.1078/0171-2985-00128 }}
* {{cite journal | vauthors = te Velde AA, van Kooyk Y, Braat H, Hommes DW, Dellemijn TA, Slors JF, van Deventer SJ, Vyth-Dreese FA | title = Increased expression of DC-SIGN+IL-12+IL-18+ and CD83+IL-12-IL-18- dendritic cell populations in the colonic mucosa of patients with Crohn's disease | journal = Eur. J. Immunol. | volume = 33 | issue = 1 | pages = 143–51 | year = 2003 | pmid = 12594843 | doi = 10.1002/immu.200390017 }}
* {{cite journal | vauthors = Dudziak D, Kieser A, Dirmeier U, Nimmerjahn F, Berchtold S, Steinkasserer A, Marschall G, Hammerschmidt W, Laux G, Bornkamm GW | title = Latent Membrane Protein 1 of Epstein-Barr Virus Induces CD83 by the NF-κB Signaling Pathway | journal = J. Virol. | volume = 77 | issue = 15 | pages = 8290–8 | year = 2003 | pmid = 12857898 | pmc = 165234 | doi = 10.1128/JVI.77.15.8290-8298.2003 }}
* {{cite journal | vauthors = Hock BD, Haring LF, Steinkasserer A, Taylor KG, Patton WN, McKenzie JL | title = The soluble form of CD83 is present at elevated levels in a number of hematological malignancies | journal = Leuk. Res. | volume = 28 | issue = 3 | pages = 237–41 | year = 2004 | pmid = 14687618 | doi = 10.1016/S0145-2126(03)00255-8 }}
* {{cite journal | vauthors = Sénéchal B, Boruchov AM, Reagan JL, Hart DN, Young JW | title = Infection of mature monocyte-derived dendritic cells with human cytomegalovirus inhibits stimulation of T-cell proliferation via the release of soluble CD83 | journal = Blood | volume = 103 | issue = 11 | pages = 4207–15 | year = 2004 | pmid = 14962896 | doi = 10.1182/blood-2003-12-4350 }}
* {{cite journal | vauthors = Cao W, Lee SH, Lu J | title = CD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cells | journal = Biochem. J. | volume = 385 | issue = Pt 1 | pages = 85–93 | year = 2005 | pmid = 15320871 | pmc = 1134676 | doi = 10.1042/BJ20040741 }}
{{refend}}


==See also==
== External links ==
* [[Cluster of differentiation]]
* {{MeshName|CD83+protein,+human}}
* {{UCSC gene info|CD83}}
 
{{Clusters of differentiation}}


==References==
[[Category:Clusters of differentiation]]
{{reflist|2}}


==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal  | author=Lechmann M, Berchtold S, Hauber J, Steinkasserer A |title=CD83 on dendritic cells: more than just a marker for maturation. |journal=Trends Immunol. |volume=23 |issue= 6 |pages= 273-5 |year= 2002 |pmid= 12072358 |doi=  }}
*{{cite journal  | author=Zhou LJ, Schwarting R, Smith HM, Tedder TF |title=A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily. |journal=J. Immunol. |volume=149 |issue= 2 |pages= 735-42 |year= 1992 |pmid= 1378080 |doi=  }}
*{{cite journal  | author=Zhou LJ, Tedder TF |title=Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. |journal=J. Immunol. |volume=154 |issue= 8 |pages= 3821-35 |year= 1995 |pmid= 7706722 |doi=  }}
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | author=Kozlow EJ, Wilson GL, Fox CH, Kehrl JH |title=Subtractive cDNA cloning of a novel member of the Ig gene superfamily expressed at high levels in activated B lymphocytes. |journal=Blood |volume=81 |issue= 2 |pages= 454-61 |year= 1993 |pmid= 8422464 |doi=  }}
*{{cite journal  | author=de la Fuente MA, Pizcueta P, Nadal M, ''et al.'' |title=CD84 leukocyte antigen is a new member of the Ig superfamily. |journal=Blood |volume=90 |issue= 6 |pages= 2398-405 |year= 1997 |pmid= 9310491 |doi=  }}
*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal  | author=Olavesen MG, Bentley E, Mason RV, ''et al.'' |title=Fine mapping of 39 ESTs on human chromosome 6p23-p25. |journal=Genomics |volume=46 |issue= 2 |pages= 303-6 |year= 1998 |pmid= 9417921 |doi= 10.1006/geno.1997.5032 }}
*{{cite journal  | author=Twist CJ, Beier DR, Disteche CM, ''et al.'' |title=The mouse Cd83 gene: structure, domain organization, and chromosome localization. |journal=Immunogenetics |volume=48 |issue= 6 |pages= 383-93 |year= 1998 |pmid= 9799334 |doi=  }}
*{{cite journal  | author=Berchtold S, Mühl-Zürbes P, Heufler C, ''et al.'' |title=Cloning, recombinant expression and biochemical characterization of the murine CD83 molecule which is specifically upregulated during dendritic cell maturation. |journal=FEBS Lett. |volume=461 |issue= 3 |pages= 211-6 |year= 1999 |pmid= 10567699 |doi=  }}
*{{cite journal  | author=Scholler N, Hayden-Ledbetter M, Hellström KE, ''et al.'' |title=CD83 is a sialic acid-binding Ig-like lectin (Siglec) adhesion receptor that binds monocytes and a subset of activated CD8+ T cells. |journal=J. Immunol. |volume=166 |issue= 6 |pages= 3865-72 |year= 2001 |pmid= 11238630 |doi=  }}
*{{cite journal  | author=Fanales-Belasio E, Moretti S, Nappi F, ''et al.'' |title=Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses. |journal=J. Immunol. |volume=168 |issue= 1 |pages= 197-206 |year= 2002 |pmid= 11751963 |doi=  }}
*{{cite journal  | author=Berchtold S, Mühl-Zürbes P, Maczek E, ''et al.'' |title=Cloning and characterization of the promoter region of the human CD83 gene. |journal=Immunobiology |volume=205 |issue= 3 |pages= 231-46 |year= 2003 |pmid= 12182451 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=te Velde AA, van Kooyk Y, Braat H, ''et al.'' |title=Increased expression of DC-SIGN+IL-12+IL-18+ and CD83+IL-12-IL-18- dendritic cell populations in the colonic mucosa of patients with Crohn's disease. |journal=Eur. J. Immunol. |volume=33 |issue= 1 |pages= 143-51 |year= 2003 |pmid= 12594843 |doi= 10.1002/immu.200390017 }}
*{{cite journal  | author=Dudziak D, Kieser A, Dirmeier U, ''et al.'' |title=Latent membrane protein 1 of Epstein-Barr virus induces CD83 by the NF-kappaB signaling pathway. |journal=J. Virol. |volume=77 |issue= 15 |pages= 8290-8 |year= 2003 |pmid= 12857898 |doi=  }}
*{{cite journal  | author=Hock BD, Haring LF, Steinkasserer A, ''et al.'' |title=The soluble form of CD83 is present at elevated levels in a number of hematological malignancies. |journal=Leuk. Res. |volume=28 |issue= 3 |pages= 237-41 |year= 2004 |pmid= 14687618 |doi=  }}
*{{cite journal  | author=Sénéchal B, Boruchov AM, Reagan JL, ''et al.'' |title=Infection of mature monocyte-derived dendritic cells with human cytomegalovirus inhibits stimulation of T-cell proliferation via the release of soluble CD83. |journal=Blood |volume=103 |issue= 11 |pages= 4207-15 |year= 2004 |pmid= 14962896 |doi= 10.1182/blood-2003-12-4350 }}
*{{cite journal  | author=Cao W, Lee SH, Lu J |title=CD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cells. |journal=Biochem. J. |volume=385 |issue= Pt 1 |pages= 85-93 |year= 2005 |pmid= 15320871 |doi= 10.1042/BJ20040741 }}
}}
{{refend}}


{{membrane-protein-stub}}
{{membrane-protein-stub}}
{{Clusters of differentiation}}
[[Category:Clusters of differentiation|*]]
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{{WikiDoc Sources}}

Latest revision as of 09:24, 30 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

CD83 (Cluster of Differentiation 83) is a human protein encoded by the CD83 gene.[1]

See also

References

  1. ↑ "Entrez Gene: CD83 CD83 molecule".

Further reading

  • Lechmann M, Berchtold S, Hauber J, Steinkasserer A (2002). "CD83 on dendritic cells: more than just a marker for maturation". Trends Immunol. 23 (6): 273–5. doi:10.1016/S1471-4906(02)02214-7. PMID 12072358.
  • Zhou LJ, Schwarting R, Smith HM, Tedder TF (1992). "A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily". J. Immunol. 149 (2): 735–42. PMID 1378080.
  • Zhou LJ, Tedder TF (1995). "Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily". J. Immunol. 154 (8): 3821–35. PMID 7706722.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Kozlow EJ, Wilson GL, Fox CH, Kehrl JH (1993). "Subtractive cDNA cloning of a novel member of the Ig gene superfamily expressed at high levels in activated B lymphocytes". Blood. 81 (2): 454–61. PMID 8422464.
  • de la Fuente MA, Pizcueta P, Nadal M, Bosch J, Engel P (1997). "CD84 leukocyte antigen is a new member of the Ig superfamily". Blood. 90 (6): 2398–405. PMID 9310491.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Olavesen MG, Bentley E, Mason RV, Stephens RJ, Ragoussis J (1998). "Fine mapping of 39 ESTs on human chromosome 6p23-p25". Genomics. 46 (2): 303–6. doi:10.1006/geno.1997.5032. PMID 9417921.
  • Twist CJ, Beier DR, Disteche CM, Edelhoff S, Tedder TF (1998). "The mouse Cd83 gene: structure, domain organization, and chromosome localization". Immunogenetics. 48 (6): 383–93. doi:10.1007/s002510050449. PMID 9799334.
  • Berchtold S, Mühl-Zürbes P, Heufler C, Winklehner P, Schuler G, Steinkasserer A (1999). "Cloning, recombinant expression and biochemical characterization of the murine CD83 molecule which is specifically upregulated during dendritic cell maturation". FEBS Lett. 461 (3): 211–6. doi:10.1016/S0014-5793(99)01465-9. PMID 10567699.
  • Scholler N, Hayden-Ledbetter M, Hellström KE, Hellström I, Ledbetter JA (2001). "CD83 is a sialic acid-binding Ig-like lectin (Siglec) adhesion receptor that binds monocytes and a subset of activated CD8+ T cells". J. Immunol. 166 (6): 3865–72. doi:10.4049/jimmunol.166.6.3865. PMID 11238630.
  • Fanales-Belasio E, Moretti S, Nappi F, Barillari G, Micheletti F, Cafaro A, Ensoli B (2002). "Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses". J. Immunol. 168 (1): 197–206. doi:10.4049/jimmunol.168.1.197. PMID 11751963.
  • Berchtold S, Mühl-Zürbes P, Maczek E, Golka A, Schuler G, Steinkasserer A (2003). "Cloning and characterization of the promoter region of the human CD83 gene". Immunobiology. 205 (3): 231–46. doi:10.1078/0171-2985-00128. PMID 12182451.
  • te Velde AA, van Kooyk Y, Braat H, Hommes DW, Dellemijn TA, Slors JF, van Deventer SJ, Vyth-Dreese FA (2003). "Increased expression of DC-SIGN+IL-12+IL-18+ and CD83+IL-12-IL-18- dendritic cell populations in the colonic mucosa of patients with Crohn's disease". Eur. J. Immunol. 33 (1): 143–51. doi:10.1002/immu.200390017. PMID 12594843.
  • Dudziak D, Kieser A, Dirmeier U, Nimmerjahn F, Berchtold S, Steinkasserer A, Marschall G, Hammerschmidt W, Laux G, Bornkamm GW (2003). "Latent Membrane Protein 1 of Epstein-Barr Virus Induces CD83 by the NF-κB Signaling Pathway". J. Virol. 77 (15): 8290–8. doi:10.1128/JVI.77.15.8290-8298.2003. PMC 165234. PMID 12857898.
  • Hock BD, Haring LF, Steinkasserer A, Taylor KG, Patton WN, McKenzie JL (2004). "The soluble form of CD83 is present at elevated levels in a number of hematological malignancies". Leuk. Res. 28 (3): 237–41. doi:10.1016/S0145-2126(03)00255-8. PMID 14687618.
  • Sénéchal B, Boruchov AM, Reagan JL, Hart DN, Young JW (2004). "Infection of mature monocyte-derived dendritic cells with human cytomegalovirus inhibits stimulation of T-cell proliferation via the release of soluble CD83". Blood. 103 (11): 4207–15. doi:10.1182/blood-2003-12-4350. PMID 14962896.
  • Cao W, Lee SH, Lu J (2005). "CD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cells". Biochem. J. 385 (Pt 1): 85–93. doi:10.1042/BJ20040741. PMC 1134676. PMID 15320871.

External links


Retrieved from "https://www.wikidoc.org/index.php?title=CD83&oldid=1420836"