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{{ | '''CD177 antigen''' is a [[protein]] that in humans is encoded by the ''CD177'' [[gene]].<ref name="pmid10753836">{{cite journal | vauthors = Temerinac S, Klippel S, Strunck E, Roder S, Lubbert M, Lange W, Azemar M, Meinhardt G, Schaefer HE, Pahl HL | title = Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera | journal = Blood | volume = 95 | issue = 8 | pages = 2569–76 |date=May 2000 | pmid = 10753836 | pmc = | doi = }}</ref><ref name="pmid5552408">{{cite journal | vauthors = Lalezari P, Murphy GB, ((Allen FH Jr)) | title = NB1, a new neutrophil-specific antigen involved in the pathogenesis of neonatal neutropenia | journal = J Clin Invest | volume = 50 | issue = 5 | pages = 1108–15 |date=Jun 1971 | pmid = 5552408 | pmc = 292033 | doi = 10.1172/JCI106582 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CD177 CD177 molecule| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57126| accessdate = }}</ref> | ||
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| summary_text = NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia (Lalezari et al., 1971).[supplied by OMIM]<ref name="entrez" | | summary_text = NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia (Lalezari et al., 1971). [supplied by OMIM]<ref name="entrez" /> | ||
}} | }} | ||
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==References== | ==References== | ||
{{reflist | {{reflist}} | ||
==Further reading== | ==Further reading== | ||
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*{{cite journal | author=Stroncek D |title=Neutrophil-specific antigen HNA-2a (NB1, CD177): serology, biochemistry, and molecular biology | *{{cite journal | author=Stroncek D |title=Neutrophil-specific antigen HNA-2a (NB1, CD177): serology, biochemistry, and molecular biology |journal=Vox Sang. |volume=83 Suppl 1 |issue= |pages= 359–61 |year= 2003 |pmid= 12617169 |doi= 10.1111/j.1423-0410.2002.tb05334.x}} | ||
*{{cite journal | author=Pahl HL |title=PRV-1 mRNA expression and other molecular markers in polycythemia rubra vera | *{{cite journal | author=Pahl HL |title=PRV-1 mRNA expression and other molecular markers in polycythemia rubra vera |journal=Curr. Hematol. Rep. |volume=2 |issue= 3 |pages= 231–6 |year= 2003 |pmid= 12901344 |doi= }} | ||
*{{cite journal | | *{{cite journal | vauthors=Kralovics R, Skoda RC |title=Molecular pathogenesis of Philadelphia chromosome negative myeloproliferative disorders |journal=Blood Rev. |volume=19 |issue= 1 |pages= 1–13 |year= 2005 |pmid= 15572213 |doi= 10.1016/j.blre.2004.02.002 }} | ||
*{{cite journal | author=Goldschmeding R | *{{cite journal | author=Goldschmeding R |title=Further characterization of the NB 1 antigen as a variably expressed 56-62 kD GPI-linked glycoprotein of plasma membranes and specific granules of neutrophils |journal=Br. J. Haematol. |volume=81 |issue= 3 |pages= 336–45 |year= 1992 |pmid= 1382544 |doi=10.1111/j.1365-2141.1992.tb08237.x |name-list-format=vanc| author2=van Dalen CM | author3=Faber N | display-authors=3 | last4=Calafat | first4=J. | last5=Huizinga | first5=T. W. J. | last6=Schoot | first6=C. E. | last7=Clement | first7=L. T. | last8=Borne | first8=A. E. G. Kr. }} | ||
*{{cite journal | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }} | |||
*{{cite journal | | *{{cite journal | vauthors=Stroncek DF, Herr GP, Plachta LB |title=Neutrophil-specific antigen NB1 inhibits neutrophil-endothelial cell interactions |journal=J. Lab. Clin. Med. |volume=123 |issue= 2 |pages= 247–55 |year= 1994 |pmid= 8301201 |doi= }} | ||
*{{cite journal | | *{{cite journal | author=Suzuki Y |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 |name-list-format=vanc| author2=Yoshitomo-Nakagawa K | author3=Maruyama K | display-authors=3 | last4=Suyama | first4=A | last5=Sugano | first5=S }} | ||
*{{cite journal | author=Suzuki Y | *{{cite journal | author=Kissel K |title=Molecular basis of the neutrophil glycoprotein NB1 (CD177) involved in the pathogenesis of immune neutropenias and transfusion reactions |journal=Eur. J. Immunol. |volume=31 |issue= 5 |pages= 1301–9 |year= 2001 |pmid= 11465086 |doi= 10.1002/1521-4141(200105)31:5<1301::AID-IMMU1301>3.0.CO;2-J |name-list-format=vanc| author2=Santoso S | author3=Hofmann C | display-authors=3 | last4=Stroncek | first4=David | last5=Bux | first5=Jürgen }} | ||
*{{cite journal | vauthors=Bettinotti MP, Olsen A, Stroncek D |title=The use of bioinformatics to identify the genomic structure of the gene that encodes neutrophil antigen NB1, CD177 |journal=Clin. Immunol. |volume=102 |issue= 2 |pages= 138–44 |year= 2002 |pmid= 11846455 |doi= 10.1006/clim.2001.5154 }} | |||
*{{cite journal | author=Kissel K | *{{cite journal | vauthors=Kissel K, Scheffler S, Kerowgan M, Bux J |title=Molecular basis of NB1 (HNA-2a, CD177) deficiency |journal=Blood |volume=99 |issue= 11 |pages= 4231–3 |year= 2002 |pmid= 12010833 |doi=10.1182/blood.V99.11.4231 }} | ||
*{{cite journal | author=Klippel S |title=Biochemical characterization of PRV-1, a novel hematopoietic cell surface receptor, which is overexpressed in polycythemia rubra vera |journal=Blood |volume=100 |issue= 7 |pages= 2441–8 |year= 2002 |pmid= 12239154 |doi= 10.1182/blood-2002-03-0949 |name-list-format=vanc| author2=Strunck E | author3=Busse CE | display-authors=3 | last4=Behringer | first4=D | last5=Pahl | first5=HL }} | |||
*{{cite journal | | *{{cite journal | author=Teofili L |title=Overexpression of the polycythemia rubra vera-1 gene in essential thrombocythemia |journal=J. Clin. Oncol. |volume=20 |issue= 20 |pages= 4249–54 |year= 2002 |pmid= 12377969 |doi=10.1200/JCO.2002.11.507 |name-list-format=vanc| author2=Martini M | author3=Luongo M | display-authors=3 | last4=Di Mario | first4=A | last5=Leone | first5=G | last6=De Stefano | first6=V | last7=Larocca | first7=LM }} | ||
*{{cite journal | | *{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }} | ||
*{{cite journal | author= | *{{cite journal | author=Najfeld V |title=Fluorescence in situ hybridization analysis of the PRV-1 gene in polycythemia vera: implications for its role in diagnosis and pathogenesis |journal=Exp. Hematol. |volume=31 |issue= 2 |pages= 118–21 |year= 2003 |pmid= 12591276 |doi=10.1016/S0301-472X(02)01032-9 |name-list-format=vanc| author2=Fuchs S | author3=Merando P | display-authors=3 | last4=Lezon-Geyda | first4=Kimberly | last5=Fruchtman | first5=Steven }} | ||
*{{cite journal | author=Wolff J |title=Lack of NB1 GP (CD177/HNA-2a) gene transcription in NB1 GP- neutrophils from NB1 GP-expressing individuals and association of low expression with NB1 gene polymorphisms |journal=Blood |volume=102 |issue= 2 |pages= 731–3 |year= 2003 |pmid= 12623849 |doi= 10.1182/blood-2002-09-2831 |name-list-format=vanc| author2=Brendel C | author3=Fink L | display-authors=3 | last4=Bohle | first4=RM | last5=Kissel | first5=K | last6=Bux | first6=J }} | |||
*{{cite journal | author=Johansson P |title=The presence of a significant association between elevated PRV-1 mRNA expression and low plasma erythropoietin concentration in essential thrombocythaemia |journal=Eur. J. Haematol. |volume=70 |issue= 6 |pages= 358–62 |year= 2003 |pmid= 12756017 |doi=10.1034/j.1600-0609.2003.00079.x |name-list-format=vanc| author2=Andréasson B | author3=Safai-Kutti S | display-authors=3 | last4=Wennström | first4=Lovisa | last5=Palmqvist | first5=Lars | last6=Ricksten | first6=Anne | last7=Lindstedt | first7=Göran | last8=Kutti | first8=Jack }} | |||
*{{cite journal | author= | |||
}} | }} | ||
{{refend}} | {{refend}} | ||
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==External links== | ==External links== | ||
* {{MeshName|CD177+Antigen}} | * {{MeshName|CD177+Antigen}} | ||
* {{UCSC gene info|CD177}} | |||
{{Clusters of differentiation}} | {{Clusters of differentiation}} | ||
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[[Category:Clusters of differentiation]] | [[Category:Clusters of differentiation]] | ||
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Revision as of 09:21, 30 August 2017
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External IDs | GeneCards: [1] | ||||||
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Species | Human | Mouse | |||||
Entrez |
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Ensembl |
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UniProt |
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RefSeq (mRNA) |
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RefSeq (protein) |
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Location (UCSC) | n/a | n/a | |||||
PubMed search | n/a | n/a | |||||
Wikidata | |||||||
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CD177 antigen is a protein that in humans is encoded by the CD177 gene.[1][2][3]
NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia (Lalezari et al., 1971). [supplied by OMIM][3]
See also
References
- ↑ Temerinac S, Klippel S, Strunck E, Roder S, Lubbert M, Lange W, Azemar M, Meinhardt G, Schaefer HE, Pahl HL (May 2000). "Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera". Blood. 95 (8): 2569–76. PMID 10753836.
- ↑ Lalezari P, Murphy GB, Allen FH Jr (Jun 1971). "NB1, a new neutrophil-specific antigen involved in the pathogenesis of neonatal neutropenia". J Clin Invest. 50 (5): 1108–15. doi:10.1172/JCI106582. PMC 292033. PMID 5552408.
- ↑ 3.0 3.1 "Entrez Gene: CD177 CD177 molecule".
Further reading
- Stroncek D (2003). "Neutrophil-specific antigen HNA-2a (NB1, CD177): serology, biochemistry, and molecular biology". Vox Sang. 83 Suppl 1: 359–61. doi:10.1111/j.1423-0410.2002.tb05334.x. PMID 12617169.
- Pahl HL (2003). "PRV-1 mRNA expression and other molecular markers in polycythemia rubra vera". Curr. Hematol. Rep. 2 (3): 231–6. PMID 12901344.
- Kralovics R, Skoda RC (2005). "Molecular pathogenesis of Philadelphia chromosome negative myeloproliferative disorders". Blood Rev. 19 (1): 1–13. doi:10.1016/j.blre.2004.02.002. PMID 15572213.
- Goldschmeding R, van Dalen CM, Faber N, et al. (1992). "Further characterization of the NB 1 antigen as a variably expressed 56-62 kD GPI-linked glycoprotein of plasma membranes and specific granules of neutrophils". Br. J. Haematol. 81 (3): 336–45. doi:10.1111/j.1365-2141.1992.tb08237.x. PMID 1382544.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Stroncek DF, Herr GP, Plachta LB (1994). "Neutrophil-specific antigen NB1 inhibits neutrophil-endothelial cell interactions". J. Lab. Clin. Med. 123 (2): 247–55. PMID 8301201.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Kissel K, Santoso S, Hofmann C, et al. (2001). "Molecular basis of the neutrophil glycoprotein NB1 (CD177) involved in the pathogenesis of immune neutropenias and transfusion reactions". Eur. J. Immunol. 31 (5): 1301–9. doi:10.1002/1521-4141(200105)31:5<1301::AID-IMMU1301>3.0.CO;2-J. PMID 11465086.
- Bettinotti MP, Olsen A, Stroncek D (2002). "The use of bioinformatics to identify the genomic structure of the gene that encodes neutrophil antigen NB1, CD177". Clin. Immunol. 102 (2): 138–44. doi:10.1006/clim.2001.5154. PMID 11846455.
- Kissel K, Scheffler S, Kerowgan M, Bux J (2002). "Molecular basis of NB1 (HNA-2a, CD177) deficiency". Blood. 99 (11): 4231–3. doi:10.1182/blood.V99.11.4231. PMID 12010833.
- Klippel S, Strunck E, Busse CE, et al. (2002). "Biochemical characterization of PRV-1, a novel hematopoietic cell surface receptor, which is overexpressed in polycythemia rubra vera". Blood. 100 (7): 2441–8. doi:10.1182/blood-2002-03-0949. PMID 12239154.
- Teofili L, Martini M, Luongo M, et al. (2002). "Overexpression of the polycythemia rubra vera-1 gene in essential thrombocythemia". J. Clin. Oncol. 20 (20): 4249–54. doi:10.1200/JCO.2002.11.507. PMID 12377969.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Najfeld V, Fuchs S, Merando P, et al. (2003). "Fluorescence in situ hybridization analysis of the PRV-1 gene in polycythemia vera: implications for its role in diagnosis and pathogenesis". Exp. Hematol. 31 (2): 118–21. doi:10.1016/S0301-472X(02)01032-9. PMID 12591276.
- Wolff J, Brendel C, Fink L, et al. (2003). "Lack of NB1 GP (CD177/HNA-2a) gene transcription in NB1 GP- neutrophils from NB1 GP-expressing individuals and association of low expression with NB1 gene polymorphisms". Blood. 102 (2): 731–3. doi:10.1182/blood-2002-09-2831. PMID 12623849.
- Johansson P, Andréasson B, Safai-Kutti S, et al. (2003). "The presence of a significant association between elevated PRV-1 mRNA expression and low plasma erythropoietin concentration in essential thrombocythaemia". Eur. J. Haematol. 70 (6): 358–62. doi:10.1034/j.1600-0609.2003.00079.x. PMID 12756017.
External links
- CD177+Antigen at the US National Library of Medicine Medical Subject Headings (MeSH)
- Human CD177 genome location and CD177 gene details page in the UCSC Genome Browser.
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