BST1

Bone marrow stromal cell antigen 1
PDB rendering based on 1isf.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1isf​, 1isg​, 1ish​, 1isi​, 1isj​, 1ism​
Identifiers
Symbols	BST1 ; CD157
External IDs	Template:OMIM5 Template:MGI HomoloGene: 3198
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Bone marrow stromal cell antigen 1, also known as BST1, is a human gene.

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.

See also

• Cluster of differentiation

Further reading

• Ortolan E, Vacca P, Capobianco A; et al. (2003). "CD157, the Janus of CD38 but with a unique personality". Cell Biochem. Funct. 20 (4): 309–22. doi:10.1002/cbf.978. PMID 12415565.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kaisho T, Ishikawa J, Oritani K; et al. (1994). "BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth". Proc. Natl. Acad. Sci. U.S.A. 91 (12): 5325–9. PMID 8202488.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lee BO, Ishihara K, Denno K; et al. (1996). "Elevated levels of the soluble form of bone marrow stromal cell antigen 1 in the sera of patients with severe rheumatoid arthritis". Arthritis Rheum. 39 (4): 629–37. PMID 8630113.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kajimoto Y, Miyagawa J, Ishihara K; et al. (1996). "Pancreatic islet cells express BST-1, a CD38-like surface molecule having ADP-ribosyl cyclase activity". Biochem. Biophys. Res. Commun. 219 (3): 941–6. PMID 8645283.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Okuyama Y, Ishihara K, Kimura N; et al. (1997). "Human BST-1 expressed on myeloid cells functions as a receptor molecule". Biochem. Biophys. Res. Commun. 228 (3): 838–45. doi:10.1006/bbrc.1996.1741. PMID 8941363.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Muraoka O, Tanaka H, Itoh M; et al. (1997). "Genomic structure of human BST-1". Immunol. Lett. 54 (1): 1–4. PMID 9030974.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wimazal F, Ghannadan M, Müller MR; et al. (2000). "Expression of homing receptors and related molecules on human mast cells and basophils: a comparative analysis using multi-color flow cytometry and toluidine blue/immunofluorescence staining techniques". Tissue Antigens. 54 (5): 499–507. PMID 10599889.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yamamoto-Katayama S, Sato A, Ariyoshi M; et al. (2001). "Site-directed removal of N-glycosylation sites in BST-1/CD157: effects on molecular and functional heterogeneity". Biochem. J. 357 (Pt 2): 385–92. PMID 11439087.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liang F, Qi RZ, Chang CF (2001). "Signalling of GPI-anchored CD157 via focal adhesion kinase in MCA102 fibroblasts". FEBS Lett. 506 (3): 207–10. PMID 11602246.CS1 maint: Multiple names: authors list (link)
• Yamamoto-Katayama S, Ariyoshi M, Ishihara K; et al. (2002). "Crystallographic studies on human BST-1/CD157 with ADP-ribosyl cyclase and NAD glycohydrolase activities". J. Mol. Biol. 316 (3): 711–23. doi:10.1006/jmbi.2001.5386. PMID 11866528.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Funaro A, Ortolan E, Ferranti B; et al. (2005). "CD157 is an important mediator of neutrophil adhesion and migration". Blood. 104 (13): 4269–78. doi:10.1182/blood-2004-06-2129. PMID 15328157.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hillier LW, Graves TA, Fulton RS; et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liu T, Qian WJ, Gritsenko MA; et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMID 16335952.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.