SEMA7A

Semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
Identifiers
Symbols	SEMA7A ; CD108; CDw108; H-SEMA-K1; H-Sema K1; H-Sema-L; JMH; MGC126692; MGC126696; SEMAK1; SEMAL
External IDs	Template:OMIM5 Template:MGI HomoloGene: 2678
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SEMA7A 210083 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

WikiDoc Resources for SEMA7A
Articles
Most recent articles on SEMA7A Most cited articles on SEMA7A Review articles on SEMA7A Articles on SEMA7A in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on SEMA7A Images of SEMA7A Photos of SEMA7A Podcasts & MP3s on SEMA7A Videos on SEMA7A
Evidence Based Medicine
Cochrane Collaboration on SEMA7A Bandolier on SEMA7A TRIP on SEMA7A
Clinical Trials
Ongoing Trials on SEMA7A at Clinical Trials.gov Trial results on SEMA7A Clinical Trials on SEMA7A at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on SEMA7A NICE Guidance on SEMA7A NHS PRODIGY Guidance FDA on SEMA7A CDC on SEMA7A
Books
Books on SEMA7A
News
SEMA7A in the news Be alerted to news on SEMA7A News trends on SEMA7A
Commentary
Blogs on SEMA7A
Definitions
Definitions of SEMA7A
Patient Resources / Community
Patient resources on SEMA7A Discussion groups on SEMA7A Patient Handouts on SEMA7A Directions to Hospitals Treating SEMA7A Risk calculators and risk factors for SEMA7A
Healthcare Provider Resources
Symptoms of SEMA7A Causes & Risk Factors for SEMA7A Diagnostic studies for SEMA7A Treatment of SEMA7A
Continuing Medical Education (CME)
CME Programs on SEMA7A
International
SEMA7A en Espanol SEMA7A en Francais
Business
SEMA7A in the Marketplace Patents on SEMA7A
Experimental / Informatics
List of terms related to SEMA7A

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) (SEMA7A) also known as CD108 (Cluster of Differentiation 108), is a human gene.

SEMA7A is a membrane-bound semaphorin that associates with cell surfaces via a glycosylphosphatidylinositol (GPI) linkage. SEMA7A is also known as the John-Milton-Hagen (JMH) blood group antigen, an 80-kD glycoprotein expressed on activated lymphocytes and erythrocytes.[supplied by OMIM]

See also

• Cluster of differentiation

Further reading

• Xu X, Ng S, Wu ZL; et al. (1998). "Human semaphorin K1 is glycosylphosphatidylinositol-linked and defines a new subfamily of viral-related semaphorins". J. Biol. Chem. 273 (35): 22428–34. PMID 9712866.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lange C, Liehr T, Goen M; et al. (1998). "New eukaryotic semaphorins with close homology to semaphorins of DNA viruses". Genomics. 51 (3): 340–50. doi:10.1006/geno.1998.5256. PMID 9721204.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yamada A, Kubo K, Takeshita T; et al. (1999). "Molecular cloning of a glycosylphosphatidylinositol-anchored molecule CDw108". J. Immunol. 162 (7): 4094–100. PMID 10201933.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Angelisová P, Drbal K, Cerný J; et al. (1999). "Characterization of the human leukocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules". Immunobiology. 200 (2): 234–45. PMID 10416131.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tamagnone L, Artigiani S, Chen H; et al. (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates". Cell. 99 (1): 71–80. PMID 10520995.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mine T, Harada K, Matsumoto T; et al. (2000). "CDw108 expression during T-cell development". Tissue Antigens. 55 (5): 429–36. PMID 10885563.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Holmes S, Downs AM, Fosberry A; et al. (2002). "Sema7A is a potent monocyte stimulator". Scand. J. Immunol. 56 (3): 270–5. PMID 12193228.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Maurin JC, Delorme G, Machuca-Gayet I; et al. (2005). "Odontoblast expression of semaphorin 7A during innervation of human dentin". Matrix Biol. 24 (3): 232–8. doi:10.1016/j.matbio.2005.03.005. PMID 15907379.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hu Y, Malone JP, Fagan AM; et al. (2006). "Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid". Mol. Cell Proteomics. 4 (12): 2000–9. doi:10.1074/mcp.M500207-MCP200. PMID 16199891.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Koh JM, Oh B, Lee JY; et al. (2006). "Association study of semaphorin 7a (sema7a) polymorphisms with bone mineral density and fracture risk in postmenopausal Korean women". J. Hum. Genet. 51 (2): 112–7. doi:10.1007/s10038-005-0331-z. PMID 16372136.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• SEMA7A+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.