CD59 glycoprotein, also known as MAC-inhibitory protein (MAC-IP), membrane inhibitor of reactive lysis (MIRL), or protectin, is a protein that in humans is encoded by the CD59gene.[1] It belongs to the LY6/uPAR/alpha-neurotoxinprotein family.[2]
↑ 2.02.1Maio M, Brasoveanu LI, Coral S, Sigalotti L, Lamaj E, Gasparollo A, Visintin A, Altomonte M, Fonsatti E (Aug 1998). "Structure, distribution, and functional role of protectin (CD59) in complement-susceptibility and in immunotherapy of human malignancies (Review)". international journal of oncology. 13 (2): 305–18. doi:10.3892/ijo.13.2.305. PMID9664126.
↑Huang Y, Qiao F, Abagyan R, Hazard S, Tomlinson S (September 2006). "Defining the CD59-C9 binding interaction". J. Biol. Chem. 281 (37): 27398–27404. doi:10.1074/jbc.M603690200. PMID16844690.
Holmes CH, Simpson KL, Okada H, et al. (1992). "Complement regulatory proteins at the feto-maternal interface during human placental development: distribution of CD59 by comparison with membrane cofactor protein (CD46) and decay accelerating factor (CD55)". Eur. J. Immunol. 22 (6): 1579–1585. doi:10.1002/eji.1830220635. PMID1376264.
Hahn WC, Menu E, Bothwell AL, et al. (1992). "Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59". Science. 256 (5065): 1805–1807. doi:10.1126/science.1377404. PMID1377404.
Ninomiya H, Sims PJ (1992). "The human complement regulatory protein CD59 binds to the alpha-chain of C8 and to the "b"domain of C9". J. Biol. Chem. 267 (19): 13675–80. PMID1377690.
Motoyama N, Okada N, Yamashina M, Okada H (1992). "Paroxysmal nocturnal hemoglobinuria due to hereditary nucleotide deletion in the HRF20 (CD59) gene". Eur. J. Immunol. 22 (10): 2669–2673. doi:10.1002/eji.1830221029. PMID1382994.
Tone M, Walsh LA, Waldmann H (1992). "Gene structure of human CD59 and demonstration that discrete mRNAs are generated by alternative polyadenylation". J. Mol. Biol. 227 (3): 971–976. doi:10.1016/0022-2836(92)90239-G. PMID1383553.
Philbrick WM, Palfree RG, Maher SE, et al. (1990). "The CD59 antigen is a structural homologue of murine Ly-6 antigens but lacks interferon inducibility". Eur. J. Immunol. 20 (1): 87–92. doi:10.1002/eji.1830200113. PMID1689664.
Sawada R, Ohashi K, Anaguchi H, et al. (1990). "Isolation and expression of the full-length cDNA encoding CD59 antigen of human lymphocytes". DNA Cell Biol. 9 (3): 213–220. doi:10.1089/dna.1990.9.213. PMID1692709.
Yamashina M, Ueda E, Kinoshita T, et al. (1990). "Inherited complete deficiency of 20-kilodalton homologous restriction factor (CD59) as a cause of paroxysmal nocturnal hemoglobinuria". N. Engl. J. Med. 323 (17): 1184–1189. doi:10.1056/NEJM199010253231707. PMID1699124.
Sugita Y, Tobe T, Oda E, et al. (1990). "Molecular cloning and characterization of MACIF, an inhibitor of membrane channel formation of complement". J. Biochem. 106 (4): 555–7. PMID2606909.
Bora NS, Gobleman CL, Atkinson JP, et al. (1994). "Differential expression of the complement regulatory proteins in the human eye". Invest. Ophthalmol. Vis. Sci. 34 (13): 3579–84. PMID7505007.
Kieffer B, Driscoll PC, Campbell ID, et al. (1994). "Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins". Biochemistry. 33 (15): 4471–4482. doi:10.1021/bi00181a006. PMID7512825.
Kennedy SP, Rollins SA, Burton WV, et al. (1994). "Protection of porcine aortic endothelial cells from complement-mediated cell lysis and activation by recombinant human CD59". Transplantation. 57 (10): 1494–501. doi:10.1097/00007890-199405000-00017. PMID7515200.
1erg: THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE EXTRACELLULAR REGION OF THE COMPLEMENT REGULATORY PROTEIN, CD59, A NEW CELL SURFACE PROTEIN DOMAIN RELATED TO NEUROTOXINS
1erh: THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE EXTRACELLULAR REGION OF THE COMPLEMENT REGULATORY PROTEIN, CD59, A NEW CELL SURFACE PROTEIN DOMAIN RELATED TO NEUROTOXINS