ICOSLG
| Inducible T-cell co-stimulator ligand | |||||||||||
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| Identifiers | |||||||||||
| Symbols | ICOSLG ; B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; KIAA0653; LICOS | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 49412 | ||||||||||
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| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
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| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
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Inducible T-cell co-stimulator ligand, also known as ICOSLG, is a human gene.[1] ICOSLG has also been designated as CD275 (cluster of differentiation 275).
References
Further reading
- Flesch IE (2003). "Inducible costimulator-ligand (ICOS-L)". J. Biol. Regul. Homeost. Agents. 16 (3): 217–9. PMID 12456022.
- Ishikawa K, Nagase T, Suyama M; et al. (1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. PMID 9734811.
- Ling V, Wu PW, Finnerty HF; et al. (2000). "Cutting edge: identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor". J. Immunol. 164 (4): 1653–7. PMID 10657606.
- Aicher A, Hayden-Ledbetter M, Brady WA; et al. (2000). "Characterization of human inducible costimulator ligand expression and function". J. Immunol. 164 (9): 4689–96. PMID 10779774.
- Yoshinaga SK, Zhang M, Pistillo J; et al. (2000). "Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS". Int. Immunol. 12 (10): 1439–47. PMID 11007762.
- Wang S, Zhu G, Chapoval AI; et al. (2000). "Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS". Blood. 96 (8): 2808–13. PMID 11023515.
- Ling V, Wu PW, Miyashiro JS; et al. (2001). "Differential expression of inducible costimulator-ligand splice variants: lymphoid regulation of mouse GL50-B and human GL50 molecules". J. Immunol. 166 (12): 7300–8. PMID 11390480.
- Sperling AI, Bluestone JA (2001). "ICOS costimulation: It's not just for TH2 cells anymore". Nat. Immunol. 2 (7): 573–4. doi:10.1038/89709. PMID 11429535.
- Wang S, Zhu G, Tamada K; et al. (2002). "Ligand binding sites of inducible costimulator and high avidity mutants with improved function". J. Exp. Med. 195 (8): 1033–41. PMID 11956294.
- Khayyamian S, Hutloff A, Büchner K; et al. (2002). "ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells". Proc. Natl. Acad. Sci. U.S.A. 99 (9): 6198–203. doi:10.1073/pnas.092576699. PMID 11983910.
- Akbari O, Freeman GJ, Meyer EH; et al. (2002). "Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity". Nat. Med. 8 (9): 1024–32. doi:10.1038/nm745. PMID 12145647.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Kurosawa S, Myers AC, Chen L; et al. (2003). "Expression of the costimulatory molecule B7-H2 (inducible costimulator ligand) by human airway epithelial cells". Am. J. Respir. Cell Mol. Biol. 28 (5): 563–73. doi:10.1165/rcmb.2002-0199OC. PMID 12707012.
- Chen XL, Cao XD, Kang AJ; et al. (2003). "In situ expression and significance of B7 costimulatory molecules within tissues of human gastric carcinoma". World J. Gastroenterol. 9 (6): 1370–3. PMID 12800259.
- Iwai H, Abe M, Hirose S; et al. (2003). "Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis". J. Immunol. 171 (6): 2848–54. PMID 12960306.
- Schreiner B, Wischhusen J, Mitsdoerffer M; et al. (2004). "Expression of the B7-related molecule ICOSL by human glioma cells in vitro and in vivo". Glia. 44 (3): 296–301. doi:10.1002/glia.10291. PMID 14603470.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Saatian B, Yu XY, Yu X; et al. (2004). "Expression of genes for B7-H3 and other T cell ligands by nasal epithelial cells during differentiation and activation". Am. J. Physiol. Lung Cell Mol. Physiol. 287 (1): L217–25. doi:10.1152/ajplung.00132.2003. PMID 15047568.
- Nakazawa A, Dotan I, Brimnes J; et al. (2004). "The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells". Gastroenterology. 126 (5): 1347–57. PMID 15131796.
External links
- ICOSLG+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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