Interferon gamma receptor 1
| Interferon gamma receptor 1 | |||||||||||||
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 PDB rendering based on 1fg9. | |||||||||||||
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| Symbols | IFNGR1 ; CD119; FLJ45734; IFNGR | ||||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 359 | ||||||||||||
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| Species | Human | Mouse | |||||||||||
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Interferon gamma receptor 1 (IFNGR1) also known as CD119 (Cluster of Differentiation 119), is a human gene.[1]
IFNGR1 encodes the ligand-binding chain (alpha) of the heterodimeric gamma interferon receptor. IFNGR2 encodes the non-ligand-binding partner of the heterodimeric receptor.[1]
See also
References
Further reading
- Samuel CE (2002). "Antiviral actions of interferons". Clin. Microbiol. Rev. 14 (4): 778–809, table of contents. doi:10.1128/CMR.14.4.778-809.2001. PMID 11585785.
- van Loon AP, Ozmen L, Fountoulakis M; et al. (1991). "High-affinity receptor for interferon-gamma (IFN-gamma), a ubiquitous protein occurring in different molecular forms on human cells: blood monocytes and eleven different cell lines have the same IFN-gamma receptor protein". J. Leukoc. Biol. 49 (5): 462–73. PMID 1826725.
- Le Coniat M, Alcaide-Loridan C, Fellous M, Berger R (1990). "Human interferon gamma receptor 1 (IFNGR1) gene maps to chromosome region 6q23-6q24". Hum. Genet. 84 (1): 92–4. PMID 2532616.
- Novick D, Orchansky P, Revel M, Rubinstein M (1987). "The human interferon-gamma receptor. Purification, characterization, and preparation of antibodies". J. Biol. Chem. 262 (18): 8483–7. PMID 2954953.
- Aguet M, Dembić Z, Merlin G (1988). "Molecular cloning and expression of the human interferon-gamma receptor". Cell. 55 (2): 273–80. PMID 2971451.
- Szente BE, Subramaniam PS, Johnson HM (1996). "Identification of IFN-gamma receptor binding sites for JAK2 and enhancement of binding by IFN-gamma and its C-terminal peptide IFN-gamma(95-133)". J. Immunol. 155 (12): 5617–22. PMID 7499845.
- Igarashi K, Garotta G, Ozmen L; et al. (1994). "Interferon-gamma induces tyrosine phosphorylation of interferon-gamma receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor". J. Biol. Chem. 269 (20): 14333–6. PMID 7514165.
- Walter MR, Windsor WT, Nagabhushan TL; et al. (1995). "Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor". Nature. 376 (6537): 230–5. doi:10.1038/376230a0. PMID 7617032.
- Kotenko SV, Izotova LS, Pollack BP; et al. (1995). "Interaction between the components of the interferon gamma receptor complex". J. Biol. Chem. 270 (36): 20915–21. PMID 7673114.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
- Tjoelker LW, Seyfried CE, Eddy RL; et al. (1994). "Human, mouse, and rat calnexin cDNA cloning: identification of potential calcium binding motifs and gene localization to human chromosome 5". Biochemistry. 33 (11): 3229–36. PMID 8136357.
- Greenlund AC, Farrar MA, Viviano BL, Schreiber RD (1994). "Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91)". EMBO J. 13 (7): 1591–600. PMID 8156998.
- Stüber D, Friedlein A, Fountoulakis M; et al. (1993). "Alignment of disulfide bonds of the extracellular domain of the interferon gamma receptor and investigation of their role in biological activity". Biochemistry. 32 (9): 2423–30. PMID 8443182.
- Dalton DK, Pitts-Meek S, Keshav S; et al. (1993). "Multiple defects of immune cell function in mice with disrupted interferon-gamma genes". Science. 259 (5102): 1739–42. PMID 8456300.
- Novelli F, Giovarelli M, Gentz R; et al. (1993). "Modulation of interferon-gamma receptor during human T lymphocyte alloactivation". Eur. J. Immunol. 23 (6): 1226–31. PMID 8500521.
- Newport MJ, Huxley CM, Huston S; et al. (1997). "A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection". N. Engl. J. Med. 335 (26): 1941–9. PMID 8960473.
- Jouanguy E, Altare F, Lamhamedi S; et al. (1997). "Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guérin infection". N. Engl. J. Med. 335 (26): 1956–61. PMID 8960475.
- Gerritsma JS, Gerritsen AF, De Ley M; et al. (1997). "Interferon-gamma induces biosynthesis of complement components C2, C4 and factor H by human proximal tubular epithelial cells". Cytokine. 9 (4): 276–83. doi:10.1006/cyto.1996.0164. PMID 9112336.
- Sogabe S, Stuart F, Henke C; et al. (1998). "Neutralizing epitopes on the extracellular interferon gamma receptor (IFNgammaR) alpha-chain characterized by homolog scanning mutagenesis and X-ray crystal structure of the A6 fab-IFNgammaR1-108 complex". J. Mol. Biol. 273 (4): 882–97. doi:10.1006/jmbi.1997.1336. PMID 9367779.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
External links
- IFNGR1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.