NCR2

Natural cytotoxicity triggering receptor 2
File:PBB Protein NCR2 image.jpg PDB rendering based on 1hkf.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1hkf​
Identifiers
Symbols	NCR2 ; CD336; LY95; NK-p44; NKP44; dJ149M18.1
External IDs	Template:OMIM5 HomoloGene: 88712
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE NCR2 221075 s at tn.png
File:PBB GE NCR2 217045 x at tn.png
File:PBB GE NCR2 217493 x at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Natural cytotoxicity triggering receptor 2, also known as NCR2, is a human gene. NCR2 has also been designated as CD336 (cluster of differentiation 336).

Further reading

• Hershkovitz O, Jivov S, Bloushtain N; et al. (2007). "Characterization of the recognition of tumor cells by the natural cytotoxicity receptor, NKp44". Biochemistry. 46 (25): 7426–36. doi:10.1021/bi7000455. PMID 17536787.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Forte P, Lilienfeld BG, Baumann BC, Seebach JD (2005). "Human NK cytotoxicity against porcine cells is triggered by NKp44 and NKG2D". J. Immunol. 175 (8): 5463–70. PMID 16210654.CS1 maint: Multiple names: authors list (link)
• Fuchs A, Cella M, Kondo T, Colonna M (2005). "Paradoxic inhibition of human natural interferon-producing cells by the activating receptor NKp44". Blood. 106 (6): 2076–82. doi:10.1182/blood-2004-12-4802. PMID 15941912.CS1 maint: Multiple names: authors list (link)
• Poggi A, Massaro AM, Negrini S; et al. (2005). "Tumor-induced apoptosis of human IL-2-activated NK cells: role of natural cytotoxicity receptors". J. Immunol. 174 (5): 2653–60. PMID 15728472.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nowbakht P, Ionescu MC, Rohner A; et al. (2005). "Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias". Blood. 105 (9): 3615–22. doi:10.1182/blood-2004-07-2585. PMID 15657183.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Campbell KS, Yusa S, Kikuchi-Maki A, Catina TL (2004). "NKp44 triggers NK cell activation through DAP12 association that is not influenced by a putative cytoplasmic inhibitory sequence". J. Immunol. 172 (2): 899–906. PMID 14707061.CS1 maint: Multiple names: authors list (link)
• Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cantoni C, Ponassi M, Biassoni R; et al. (2004). "The three-dimensional structure of the human NK cell receptor NKp44, a triggering partner in natural cytotoxicity". Structure. 11 (6): 725–34. PMID 12791260.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Augugliaro R, Parolini S, Castriconi R; et al. (2003). "Selective cross-talk among natural cytotoxicity receptors in human natural killer cells". Eur. J. Immunol. 33 (5): 1235–41. doi:10.1002/eji.200323896. PMID 12731048.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Eapen BR (2003). "A new insight into the pathogenesis of Reiter's syndrome using bioinformatics tools". Int. J. Dermatol. 42 (3): 242–3. PMID 12653925.
• Allcock RJ, Barrow AD, Forbes S; et al. (2003). "The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44". Eur. J. Immunol. 33 (2): 567–77. doi:10.1002/immu.200310033. PMID 12645956.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cantoni C, Ponassi M, Biassoni R; et al. (2003). "Crystallization and preliminary crystallographic characterization of the extracellular Ig-like domain of human natural killer cell activating receptor NKp44". Acta Crystallogr. D Biol. Crystallogr. 58 (Pt 10 Pt 2): 1843–5. PMID 12351833.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cantoni C, Bottino C, Vitale M; et al. (1999). "NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily". J. Exp. Med. 189 (5): 787–96. PMID 10049942.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• NCR2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)