NCR3
| Natural cytotoxicity triggering receptor 3 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | NCR3 ; 1C7; CD337; LY117; NKp30 | ||||||||||
| External IDs | HomoloGene: 51827 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE NCR3 211010 s at tn.png | |||||||||||
| File:PBB GE NCR3 210763 x at tn.png | |||||||||||
| File:PBB GE NCR3 211583 x at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Natural cytotoxicity triggering receptor 3, also known as NCR3, is a human gene.[1] NCR3 has also been designated as CD337 (cluster of differentiation 337).
References
Further reading
- Djeu JY, Jiang K, Wei S (2002). "A view to a kill: signals triggering cytotoxicity". Clin. Cancer Res. 8 (3): 636–40. PMID 11895890.
- Holzinger I, de Baey A, Messer G; et al. (1995). "Cloning and genomic characterization of LST1: a new gene in the human TNF region". Immunogenetics. 42 (5): 315–22. PMID 7590964.
- Nalabolu SR, Shukla H, Nallur G; et al. (1997). "Genes in a 220-kb region spanning the TNF cluster in human MHC". Genomics. 31 (2): 215–22. doi:10.1006/geno.1996.0034. PMID 8824804.
- de Baey A, Fellerhoff B, Maier S; et al. (1998). "Complex expression pattern of the TNF region gene LST1 through differential regulation, initiation, and alternative splicing". Genomics. 45 (3): 591–600. doi:10.1006/geno.1997.4963. PMID 9367684.
- Neville MJ, Campbell RD (1999). "A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC". J. Immunol. 162 (8): 4745–54. PMID 10202016.
- Pende D, Parolini S, Pessino A; et al. (1999). "Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells". J. Exp. Med. 190 (10): 1505–16. PMID 10562324.
- Sivakamasundari R, Raghunathan A, Zhang CY; et al. (2000). "Expression and cellular localization of the protein encoded by the 1C7 gene: a recently described component of the MHC". Immunogenetics. 51 (8–9): 723–32. PMID 10941844.
- Sato M, Ohashi J, Tsuchiya N; et al. (2002). "Identification of novel single nucleotide substitutions in the NKp30 gene expressed in human natural killer cells". Tissue Antigens. 58 (4): 255–8. PMID 11782277.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Le Bouteiller P, Barakonyi A, Giustiniani J; et al. (2003). "Engagement of CD160 receptor by HLA-C is a triggering mechanism used by circulating natural killer (NK) cells to mediate cytotoxicity". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16963–8. doi:10.1073/pnas.012681099. PMID 12486241.
- Augugliaro R, Parolini S, Castriconi R; et al. (2003). "Selective cross-talk among natural cytotoxicity receptors in human natural killer cells". Eur. J. Immunol. 33 (5): 1235–41. doi:10.1002/eji.200323896. PMID 12731048.
- Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
- Marcenaro E, Augugliaro R, Falco M; et al. (2004). "CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity". Eur. J. Immunol. 33 (12): 3367–76. doi:10.1002/eji.200324425. PMID 14635045.
- Xie T, Rowen L, Aguado B; et al. (2004). "Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse". Genome Res. 13 (12): 2621–36. doi:10.1101/gr.1736803. PMID 14656967.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Nowbakht P, Ionescu MC, Rohner A; et al. (2005). "Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias". Blood. 105 (9): 3615–22. doi:10.1182/blood-2004-07-2585. PMID 15657183.
- Poggi A, Massaro AM, Negrini S; et al. (2005). "Tumor-induced apoptosis of human IL-2-activated NK cells: role of natural cytotoxicity receptors". J. Immunol. 174 (5): 2653–60. PMID 15728472.
- Vitale M, Della Chiesa M, Carlomagno S; et al. (2005). "NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor". Blood. 106 (2): 566–71. doi:10.1182/blood-2004-10-4035. PMID 15784725.
- Warren HS, Jones AL, Freeman C; et al. (2005). "Evidence that the cellular ligand for the human NK cell activation receptor NKp30 is not a heparan sulfate glycosaminoglycan". J. Immunol. 175 (1): 207–12. PMID 15972650.
External links
- NCR3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.