Leukotriene B4 receptor
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Leukotriene B4 receptor | |||||||||||
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Identifiers | |||||||||||
Symbols | LTB4R ; BLT1; BLTR; CMKRL1; GPR16; LTB4R1; LTBR1; P2RY7; P2Y7 | ||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 22477 | ||||||||||
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Orthologs | |||||||||||
Template:GNF Ortholog box | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | n/a | n/a | |||||||||
Ensembl | n/a | n/a | |||||||||
UniProt | n/a | n/a | |||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||
RefSeq (protein) | n/a | n/a | |||||||||
Location (UCSC) | n/a | n/a | |||||||||
PubMed search | n/a | n/a |
Leukotriene B4 receptor, also known as LTB4R, is a human gene.[1]
See also
References
Further reading
- Raport CJ, Schweickart VL, Chantry D; et al. (1996). "New members of the chemokine receptor gene family". J. Leukoc. Biol. 59 (1): 18–23. PMID 8558062.
- Tager AM, Luster AD (2004). "BLT1 and BLT2: the leukotriene B(4) receptors". Prostaglandins Leukot. Essent. Fatty Acids. 69 (2–3): 123–34. PMID 12895595.
- Miyahara N, Miyahara S, Takeda K, Gelfand EW (2006). "Role of the LTB4/BLT1 pathway in allergen-induced airway hyperresponsiveness and inflammation". Allergology international : official journal of the Japanese Society of Allergology. 55 (2): 91–7. doi:10.2332/allergolint.55.91. PMID 17075244.
- Akbar GK, Dasari VR, Webb TE; et al. (1996). "Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells". J. Biol. Chem. 271 (31): 18363–7. PMID 8702478.
- Hillier LD, Lennon G, Becker M; et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. PMID 8889549.
- Owman C, Nilsson C, Lolait SJ (1997). "Cloning of cDNA encoding a putative chemoattractant receptor". Genomics. 37 (2): 187–94. doi:10.1006/geno.1996.0541. PMID 8921391.
- Yokomizo T, Izumi T, Chang K; et al. (1997). "A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis". Nature. 387 (6633): 620–4. doi:10.1038/42506. PMID 9177352.
- Maier R, Glatz A, Mosbacher J, Bilbe G (1997). "Cloning of P2Y6 cDNAs and identification of a pseudogene: comparison of P2Y receptor subtype expression in bone and brain tissues". Biochem. Biophys. Res. Commun. 237 (2): 297–302. doi:10.1006/bbrc.1997.7135. PMID 9268704.
- Gaudreau R, Le Gouill C, Métaoui S; et al. (1998). "Signalling through the leukotriene B4 receptor involves both alphai and alpha16, but not alphaq or alpha11 G-protein subunits". Biochem. J. 335 ( Pt 1): 15–8. PMID 9742207.
- Kato K, Yokomizo T, Izumi T, Shimizu T (2000). "Cell-specific transcriptional regulation of human leukotriene B(4) receptor gene". J. Exp. Med. 192 (3): 413–20. PMID 10934229.
- Yokomizo T, Kato K, Terawaki K; et al. (2000). "A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders". J. Exp. Med. 192 (3): 421–32. PMID 10934230.
- Stankova J, Turcotte S, Harris J, Rola-Pleszczynski M (2002). "Modulation of leukotriene B4 receptor-1 expression by dexamethasone: potential mechanism for enhanced neutrophil survival". J. Immunol. 168 (7): 3570–6. PMID 11907121.
- Gaudreau R, Le Gouill C, Venne MH; et al. (2002). "Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization". J. Biol. Chem. 277 (35): 31567–76. doi:10.1074/jbc.M202723200. PMID 12077128.
- Hennig R, Ding XZ, Tong WG; et al. (2002). "5-Lipoxygenase and leukotriene B(4) receptor are expressed in human pancreatic cancers but not in pancreatic ducts in normal tissue". Am. J. Pathol. 161 (2): 421–8. PMID 12163367.
- Ito N, Yokomizo T, Sasaki T; et al. (2003). "Requirement of phosphatidylinositol 3-kinase activation and calcium influx for leukotriene B4-induced enzyme release". J. Biol. Chem. 277 (47): 44898–904. doi:10.1074/jbc.M208051200. PMID 12244116.
- Tong WG, Ding XZ, Hennig R; et al. (2003). "Leukotriene B4 receptor antagonist LY293111 inhibits proliferation and induces apoptosis in human pancreatic cancer cells". Clin. Cancer Res. 8 (10): 3232–42. PMID 12374694.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Yokomizo T, Noiri E, Izumi T, Shimizu T (2003). "In vivo chemotaxis using CHO cells expressing human leukotriene B4 receptor". Adv. Exp. Med. Biol. 507: 357–61. PMID 12664610.
External links
- IUPHAR GPCR Database - Leukotriene receptors
- LTB4R+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
- Receptors,+Leukotriene+B4 at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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