GPR139: Difference between revisions

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{{Underlinked|date=October 2016}}
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{{Infobox_gene}}
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'''Probable G-protein coupled receptor 139''' is a [[protein]] that in humans is encoded by the ''GPR139'' [[gene]].<ref name="pmid12679517">{{cite journal |vauthors=Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA | title = The G protein-coupled receptor repertoires of human and mouse | journal = Proc Natl Acad Sci U S A | volume = 100 | issue = 8 | pages = 4903–8 |date=Apr 2003 | pmid = 12679517 | pmc = 153653 | doi = 10.1073/pnas.0230374100 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GPR139 G protein-coupled receptor 139| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=124274| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = G protein-coupled receptor 139
| HGNCid = 19995
| Symbol = GPR139
| AltSymbols =; GPRg1; PGR3
| OMIM = 
| ECnumber = 
| Homologene = 45860
| MGIid = 2685341
| GeneAtlas_image1 = PBB_GE_GPR139_gnf1h08229_at_tn.png
| GeneAtlas_image2 = PBB_GE_GPR139_gnf1h10318_s_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0008188 |text = neuropeptide receptor activity}} {{GNF_GO|id=GO:0046983 |text = protein dimerization activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007200 |text = G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 124274
    | Hs_Ensembl = ENSG00000180269
    | Hs_RefseqProtein = NP_001002911
    | Hs_RefseqmRNA = NM_001002911
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 16
    | Hs_GenLoc_start = 19950544
    | Hs_GenLoc_end = 19992530
    | Hs_Uniprot = Q6DWJ6
    | Mm_EntrezGene = 209776
    | Mm_Ensembl = ENSMUSG00000066197
    | Mm_RefseqmRNA = NM_001024138
    | Mm_RefseqProtein = NP_001019309
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 7
    | Mm_GenLoc_start = 118935472
    | Mm_GenLoc_end = 118975523
    | Mm_Uniprot = Q059X1
  }}
}}
'''G protein-coupled receptor 139''', also known as '''GPR139''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR139 G protein-coupled receptor 139| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=124274| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Ottolenghi C, Fellous M, Barbieri M, McElreavey K |title=Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination. |journal=Genomics |volume=79 |issue= 3 |pages= 333-43 |year= 2002 |pmid= 11863363 |doi= 10.1006/geno.2002.6711 }}
*{{cite journal  |vauthors=Ottolenghi C, Fellous M, Barbieri M, McElreavey K |title=Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination. |journal=Genomics |volume=79 |issue= 3 |pages= 333–43 |year= 2002 |pmid= 11863363 |doi= 10.1006/geno.2002.6711 }}
*{{cite journal  | author=Takeda S, Kadowaki S, Haga T, ''et al.'' |title=Identification of G protein-coupled receptor genes from the human genome sequence. |journal=FEBS Lett. |volume=520 |issue= 1-3 |pages= 97-101 |year= 2002 |pmid= 12044878 |doi= }}
*{{cite journal  |vauthors=Takeda S, Kadowaki S, Haga T |title=Identification of G protein-coupled receptor genes from the human genome sequence. |journal=FEBS Lett. |volume=520 |issue= 1–3 |pages= 97–101 |year= 2002 |pmid= 12044878 |doi=10.1016/S0014-5793(02)02775-8 |display-authors=etal}}
*{{cite journal  | author=Vassilatis DK, Hohmann JG, Zeng H, ''et al.'' |title=The G protein-coupled receptor repertoires of human and mouse. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 8 |pages= 4903-8 |year= 2003 |pmid= 12679517 |doi= 10.1073/pnas.0230374100 }}
*{{cite journal  |vauthors=Gloriam DE, Schiöth HB, Fredriksson R |title=Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship |journal=Biochim. Biophys. Acta |volume=1722 |issue= 3 |pages= 235–46 |year= 2005 |pmid= 15777626 |doi= 10.1016/j.bbagen.2004.12.001 }}
*{{cite journal  | author=Gloriam DE, Schiöth HB, Fredriksson R |title=Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship. |journal=Biochim. Biophys. Acta |volume=1722 |issue= 3 |pages= 235-46 |year= 2005 |pmid= 15777626 |doi= 10.1016/j.bbagen.2004.12.001 }}
*{{cite journal  |vauthors=Matsuo A, Matsumoto S, Nagano M |title=Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system |journal=Biochem. Biophys. Res. Commun. |volume=331 |issue= 1 |pages= 363–9 |year= 2005 |pmid= 15845401 |doi= 10.1016/j.bbrc.2005.03.174 |display-authors=etal}}
*{{cite journal  | author=Matsuo A, Matsumoto S, Nagano M, ''et al.'' |title=Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system. |journal=Biochem. Biophys. Res. Commun. |volume=331 |issue= 1 |pages= 363-9 |year= 2005 |pmid= 15845401 |doi= 10.1016/j.bbrc.2005.03.174 }}
}}
}}
{{refend}}
{{refend}}


{{membrane-protein-stub}}
{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
[[Category:G protein coupled receptors]]
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[[Category:G protein-coupled receptors]]
{{transmembranereceptor-stub}}

Latest revision as of 09:16, 10 January 2019

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

n/a

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UniProt

n/a

n/a

RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Probable G-protein coupled receptor 139 is a protein that in humans is encoded by the GPR139 gene.[1][2]


References

  1. ↑ Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA (Apr 2003). "The G protein-coupled receptor repertoires of human and mouse". Proc Natl Acad Sci U S A. 100 (8): 4903–8. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
  2. ↑ "Entrez Gene: GPR139 G protein-coupled receptor 139".

Further reading

  • Ottolenghi C, Fellous M, Barbieri M, McElreavey K (2002). "Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination". Genomics. 79 (3): 333–43. doi:10.1006/geno.2002.6711. PMID 11863363.
  • Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878.
  • Gloriam DE, Schiöth HB, Fredriksson R (2005). "Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship". Biochim. Biophys. Acta. 1722 (3): 235–46. doi:10.1016/j.bbagen.2004.12.001. PMID 15777626.
  • Matsuo A, Matsumoto S, Nagano M, et al. (2005). "Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system". Biochem. Biophys. Res. Commun. 331 (1): 363–9. doi:10.1016/j.bbrc.2005.03.174. PMID 15845401.
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