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{{Infobox_gene}}
'''Putative P2Y purinoceptor 10''' is a [[protein]] that, in humans, is encoded by the ''P2RY10'' [[gene]].<ref name="pmid11004484">{{cite journal | vauthors = Adrian K, Bernhard MK, Breitinger HG, Ogilvie A | title = Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells | journal = Biochimica et Biophysica Acta | volume = 1492 | issue = 1 | pages = 127–38 | date = June 2000 | pmid = 11004484 | pmc =  | doi = 10.1016/S0167-4781(00)00094-4 }}</ref><ref name="pmid9755289">{{cite journal | vauthors = Ralevic V, Burnstock G | title = Receptors for purines and pyrimidines | journal = Pharmacological Reviews | volume = 50 | issue = 3 | pages = 413–92 | date = September 1998 | pmid = 9755289 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: P2RY10 purinergic receptor P2Y, G-protein coupled, 10| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27334| accessdate = }}</ref>


== Function ==


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The protein encoded by this gene belongs to the family of G-protein coupled receptors that is preferentially activated by adenosine and uridine nucleotides. Two alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.<ref name="entrez" />
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== See also ==
{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Purinergic receptor P2Y, G-protein coupled, 10
| HGNCid = 19906
| Symbol = P2RY10
| AltSymbols =; P2Y10
| OMIM = 300529
| ECnumber = 
| Homologene = 8717
| MGIid = 1926076
| GeneAtlas_image1 = PBB_GE_P2RY10_214615_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0045028 |text = purinergic nucleotide receptor activity, G-protein coupled}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 27334
    | Hs_Ensembl = ENSG00000078589
    | Hs_RefseqProtein = NP_055314
    | Hs_RefseqmRNA = NM_014499
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = X
    | Hs_GenLoc_start = 78087485
    | Hs_GenLoc_end = 78104093
    | Hs_Uniprot = O00398
    | Mm_EntrezGene = 78826
    | Mm_Ensembl = ENSMUSG00000050921
    | Mm_RefseqmRNA = NM_172435
    | Mm_RefseqProtein = NP_766023
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = X
    | Mm_GenLoc_start = 103291211
    | Mm_GenLoc_end = 103307689
    | Mm_Uniprot = 
  }}
}}
'''Purinergic receptor P2Y, G-protein coupled, 10''', also known as '''P2RY10''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: P2RY10 purinergic receptor P2Y, G-protein coupled, 10| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27334| accessdate = }}</ref>
 
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{{PBB_Summary
| section_title =
| summary_text = The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. Two alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.<ref name="entrez">{{cite web | title = Entrez Gene: P2RY10 purinergic receptor P2Y, G-protein coupled, 10| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27334| accessdate = }}</ref>
}}
 
==See also==
* [[P2Y receptor]]
* [[P2Y receptor]]


==References==
== References ==
{{reflist}}
{{reflist}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin}}
{{PBB_Further_reading
* {{cite journal | vauthors = Berchtold S, Ogilvie AL, Bogdan C, Mühl-Zürbes P, Ogilvie A, Schuler G, Steinkasserer A | title = Human monocyte derived dendritic cells express functional P2X and P2Y receptors as well as ecto-nucleotidases | journal = FEBS Letters | volume = 458 | issue = 3 | pages = 424–8 | date = September 1999 | pmid = 10570953 | doi = 10.1016/S0014-5793(99)01197-7 }}
| citations =
*{{cite journal  | author=Ralevic V, Burnstock G |title=Receptors for purines and pyrimidines. |journal=Pharmacol. Rev. |volume=50 |issue= 3 |pages= 413-92 |year= 1998 |pmid= 9755289 |doi=  }}
*{{cite journal | author=Berchtold S, Ogilvie AL, Bogdan C, ''et al.'' |title=Human monocyte derived dendritic cells express functional P2X and P2Y receptors as well as ecto-nucleotidases. |journal=FEBS Lett. |volume=458 |issue= 3 |pages= 424-8 |year= 2000 |pmid= 10570953 |doi=  }}
*{{cite journal  | author=Adrian K, Bernhard MK, Breitinger HG, Ogilvie A |title=Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells. |journal=Biochim. Biophys. Acta |volume=1492 |issue= 1 |pages= 127-38 |year= 2000 |pmid= 11004484 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Ross MT, Grafham DV, Coffey AJ, ''et al.'' |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325-37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 }}
}}
{{refend}}
{{refend}}


{{NLM content}}
{{NLM content}}
{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
[[Category:G protein coupled receptors]]
{{Purinergics}}
 


{{WH}}
[[Category:G protein-coupled receptors]]
{{WS}}
{{transmembranereceptor-stub}}

Latest revision as of 18:01, 24 September 2018

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Identifiers
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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Wikidata
View/Edit Human

Putative P2Y purinoceptor 10 is a protein that, in humans, is encoded by the P2RY10 gene.[1][2][3]

Function

The protein encoded by this gene belongs to the family of G-protein coupled receptors that is preferentially activated by adenosine and uridine nucleotides. Two alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.[3]

See also

References

  1. ↑ Adrian K, Bernhard MK, Breitinger HG, Ogilvie A (June 2000). "Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells". Biochimica et Biophysica Acta. 1492 (1): 127–38. doi:10.1016/S0167-4781(00)00094-4. PMID 11004484.
  2. ↑ Ralevic V, Burnstock G (September 1998). "Receptors for purines and pyrimidines". Pharmacological Reviews. 50 (3): 413–92. PMID 9755289.
  3. ↑ 3.0 3.1 "Entrez Gene: P2RY10 purinergic receptor P2Y, G-protein coupled, 10".

Further reading

  • Berchtold S, Ogilvie AL, Bogdan C, Mühl-Zürbes P, Ogilvie A, Schuler G, Steinkasserer A (September 1999). "Human monocyte derived dendritic cells express functional P2X and P2Y receptors as well as ecto-nucleotidases". FEBS Letters. 458 (3): 424–8. doi:10.1016/S0014-5793(99)01197-7. PMID 10570953.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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