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{{Infobox_gene}}
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'''Probable G-protein coupled receptor 146''' is a [[protein]] that in humans is encoded by the ''GPR146'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR146 G protein-coupled receptor 146| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=115330| accessdate = }}</ref> It has been identified as a possible receptor for [[C-peptide]].<ref>{{cite journal | vauthors = Yosten GL, Kolar GR, Redlinger LJ, Samson WK | title = Evidence for an interaction between proinsulin C-peptide and GPR146 | journal = The Journal of Endocrinology | volume = 218 | issue = 2 | pages = B1-8 | date = 11 July 2013 | pmid = 23759446 | doi = 10.1530/JOE-13-0203 | url = http://joe.endocrinology-journals.org/content/218/2/B1.long }}</ref>
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== References ==
{{GNF_Protein_box
{{reflist}}
| image = 
| image_source = 
| PDB =
| Name = G protein-coupled receptor 146
| HGNCid = 21718
| Symbol = GPR146
| AltSymbols =; PGR8
| OMIM = 
| ECnumber = 
| Homologene = 36472
| MGIid = 1933113
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 115330
    | Hs_Ensembl = ENSG00000164849
    | Hs_RefseqProtein = NP_612454
    | Hs_RefseqmRNA = NM_138445
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 7
    | Hs_GenLoc_start = 1050769
    | Hs_GenLoc_end = 1065410
    | Hs_Uniprot = Q96CH1
    | Mm_EntrezGene = 80290
    | Mm_Ensembl = ENSMUSG00000044197
    | Mm_RefseqmRNA = NM_001038703
    | Mm_RefseqProtein = NP_001033792
    | Mm_GenLoc_db =
    | Mm_GenLoc_chr = 5
    | Mm_GenLoc_start = 139634305
    | Mm_GenLoc_end = 139650056
    | Mm_Uniprot = Q3U2L7
  }}
}}
'''G protein-coupled receptor 146''', also known as '''GPR146''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR146 G protein-coupled receptor 146| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=115330| accessdate = }}</ref>


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== Further reading ==
{{PBB_Summary
| section_title =
| summary_text =
}}
 
==References==
{{reflist|2}}
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA | title = The G protein-coupled receptor repertoires of human and mouse | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 100 | issue = 8 | pages = 4903–8 | date = Apr 2003 | pmid = 12679517 | pmc = 153653 | doi = 10.1073/pnas.0230374100 }}
| citations =
* {{cite journal | vauthors = Gloriam DE, Schiöth HB, Fredriksson R | title = Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship | journal = Biochimica et Biophysica Acta | volume = 1722 | issue = 3 | pages = 235–46 | date = Apr 2005 | pmid = 15777626 | doi = 10.1016/j.bbagen.2004.12.001 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Vassilatis DK, Hohmann JG, Zeng H, ''et al.'' |title=The G protein-coupled receptor repertoires of human and mouse. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 8 |pages= 4903-8 |year= 2003 |pmid= 12679517 |doi= 10.1073/pnas.0230374100 }}
*{{cite journal | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767-72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Gloriam DE, Schiöth HB, Fredriksson R |title=Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship. |journal=Biochim. Biophys. Acta |volume=1722 |issue= 3 |pages= 235-46 |year= 2005 |pmid= 15777626 |doi= 10.1016/j.bbagen.2004.12.001 }}
}}
{{refend}}
{{refend}}


{{membrane-protein-stub}}
{{transmembranereceptor-stub}}
{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
[[Category:G protein coupled receptors]]
[[Category:G protein-coupled receptors]]
{{WikiDoc Sources}}

Latest revision as of 18:00, 24 September 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Probable G-protein coupled receptor 146 is a protein that in humans is encoded by the GPR146 gene.[1] It has been identified as a possible receptor for C-peptide.[2]

References

  1. ↑ "Entrez Gene: GPR146 G protein-coupled receptor 146".
  2. ↑ Yosten GL, Kolar GR, Redlinger LJ, Samson WK (11 July 2013). "Evidence for an interaction between proinsulin C-peptide and GPR146". The Journal of Endocrinology. 218 (2): B1–8. doi:10.1530/JOE-13-0203. PMID 23759446.

Further reading

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