GPR39: Difference between revisions

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{{Infobox_gene}}
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'''G-protein coupled receptor 39''' is a [[protein]] that in humans is encoded by the ''GPR39'' [[gene]].<ref name="pmid9441746">{{cite journal |vauthors=McKee KK, Tan CP, Palyha OC, Liu J, Feighner SD, Hreniuk DL, Smith RG, Howard AD, Van der Ploeg LH | title = Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors | journal = Genomics | volume = 46 | issue = 3 | pages = 426–34 |date=Mar 1998 | pmid = 9441746 | pmc =  | doi = 10.1006/geno.1997.5069 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GPR39 G protein-coupled receptor 39| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2863| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = G protein-coupled receptor 39
| HGNCid = 4496
| Symbol = GPR39
| AltSymbols =; MGC149541
| OMIM = 602886
| ECnumber = 
| Homologene = 20380
| MGIid = 1918361
| GeneAtlas_image1 = PBB_GE_GPR39_208600_s_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 2863
    | Hs_Ensembl = ENSG00000183840
    | Hs_RefseqProtein = NP_001499
    | Hs_RefseqmRNA = NM_001508
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 2
    | Hs_GenLoc_start = 132891086
    | Hs_GenLoc_end = 133119649
    | Hs_Uniprot = O43194
    | Mm_EntrezGene = 71111
    | Mm_Ensembl = ENSMUSG00000026343
    | Mm_RefseqmRNA = XM_913690
    | Mm_RefseqProtein = XP_918783
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 1
    | Mm_GenLoc_start = 127504539
    | Mm_GenLoc_end = 127701399
    | Mm_Uniprot = Q9D442
  }}
}}
'''G protein-coupled receptor 39''', also known as '''GPR39''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR39 G protein-coupled receptor 39| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2863| accessdate = }}</ref>
 
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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi=  }}
*{{cite journal  |vauthors=Popovics P, Stewart AJ |title=GPR39: A Zn2+-activated G protein-coupled receptor that regulates pancreatic, gastrointestinal and neuronal functions. |journal=Cell. Mol. Life Sci. |volume=68 |issue= 1 |pages= 85–95 |year= 2011 |pmid= 20812023 |doi=10.1007/s00018-010-0517-1 }}
*{{cite journal  | author=McKee KK, Tan CP, Palyha OC, ''et al.'' |title=Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors. |journal=Genomics |volume=46 |issue= 3 |pages= 426-34 |year= 1998 |pmid= 9441746 |doi= 10.1006/geno.1997.5069 }}
*{{cite journal  |vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791  }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Holst B, Holliday ND, Bach A, ''et al.'' |title=Common structural basis for constitutive activity of the ghrelin receptor family. |journal=J. Biol. Chem. |volume=279 |issue= 51 |pages= 53806-17 |year= 2005 |pmid= 15383539 |doi= 10.1074/jbc.M407676200 }}
*{{cite journal   |vauthors=Holst B, Holliday ND, Bach A, etal |title=Common structural basis for constitutive activity of the ghrelin receptor family |journal=J. Biol. Chem. |volume=279 |issue= 51 |pages= 53806–17 |year= 2005 |pmid= 15383539 |doi= 10.1074/jbc.M407676200 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Hillier LW, Graves TA, Fulton RS, ''et al.'' |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724-31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466 }}
*{{cite journal   |vauthors=Hillier LW, Graves TA, Fulton RS, etal |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4 |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466 }}
*{{cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal   |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
*{{cite journal | author=Holst B, Egerod KL, Schild E, ''et al.'' |title=GPR39 signaling is stimulated by zinc ions but not by obestatin. |journal=Endocrinology |volume=148 |issue= 1 |pages= 13-20 |year= 2007 |pmid= 16959833 |doi= 10.1210/en.2006-0933 }}
*{{cite journal   |vauthors=Holst B, Egerod KL, Schild E, etal |title=GPR39 signaling is stimulated by zinc ions but not by obestatin |journal=Endocrinology |volume=148 |issue= 1 |pages= 13–20 |year= 2007 |pmid= 16959833 |doi= 10.1210/en.2006-0933 }}
*{{cite journal | author=Lauwers E, Landuyt B, Arckens L, ''et al.'' |title=Obestatin does not activate orphan G protein-coupled receptor GPR39. |journal=Biochem. Biophys. Res. Commun. |volume=351 |issue= 1 |pages= 21-5 |year= 2006 |pmid= 17054911 |doi= 10.1016/j.bbrc.2006.09.141 }}
*{{cite journal   |vauthors=Lauwers E, Landuyt B, Arckens L, etal |title=Obestatin does not activate orphan G protein-coupled receptor GPR39 |journal=Biochem. Biophys. Res. Commun. |volume=351 |issue= 1 |pages= 21–5 |year= 2006 |pmid= 17054911 |doi= 10.1016/j.bbrc.2006.09.141 }}
*{{cite journal | author=Egerod KL, Holst B, Petersen PS, ''et al.'' |title=GPR39 splice variants versus antisense gene LYPD1: expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue. |journal=Mol. Endocrinol. |volume=21 |issue= 7 |pages= 1685-98 |year= 2007 |pmid= 17488974 |doi= 10.1210/me.2007-0055 }}
*{{cite journal   |vauthors=Egerod KL, Holst B, Petersen PS, etal |title=GPR39 splice variants versus antisense gene LYPD1: expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue |journal=Mol. Endocrinol. |volume=21 |issue= 7 |pages= 1685–98 |year= 2007 |pmid= 17488974 |doi= 10.1210/me.2007-0055 }}
*{{cite journal | author=Yasuda S, Miyazaki T, Munechika K, ''et al.'' |title=Isolation of Zn2+ as an endogenous agonist of GPR39 from fetal bovine serum. |journal=J. Recept. Signal Transduct. Res. |volume=27 |issue= 4 |pages= 235-46 |year= 2007 |pmid= 17885920 |doi= 10.1080/10799890701506147 }}
*{{cite journal   |vauthors=Yasuda S, Miyazaki T, Munechika K, etal |title=Isolation of Zn2+ as an endogenous agonist of GPR39 from fetal bovine serum |journal=J. Recept. Signal Transduct. Res. |volume=27 |issue= 4 |pages= 235–46 |year= 2007 |pmid= 17885920 |doi= 10.1080/10799890701506147 }}
}}
}}
{{refend}}
{{refend}}


{{membrane-protein-stub}}
{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
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[[Category:G protein coupled receptors]]
[[Category:G protein coupled receptors]]
{{WikiDoc Sources}}
 
 
{{transmembranereceptor-stub}}

Revision as of 09:00, 31 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

G-protein coupled receptor 39 is a protein that in humans is encoded by the GPR39 gene.[1][2]


References

  1. ↑ McKee KK, Tan CP, Palyha OC, Liu J, Feighner SD, Hreniuk DL, Smith RG, Howard AD, Van der Ploeg LH (Mar 1998). "Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors". Genomics. 46 (3): 426–34. doi:10.1006/geno.1997.5069. PMID 9441746.
  2. ↑ "Entrez Gene: GPR39 G protein-coupled receptor 39".

Further reading


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