GPR65: Difference between revisions

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| image = 
| image_source = 
| PDB =
| Name = G protein-coupled receptor 65
| HGNCid = 4517
| Symbol = GPR65
| AltSymbols =; TDAG8; hTDAG8
| OMIM = 604620
| ECnumber = 
| Homologene = 2675
| MGIid = 108031
| GeneAtlas_image1 = PBB_GE_GPR65_214467_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0006915 |text = apoptosis}} {{GNF_GO|id=GO:0006955 |text = immune response}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 8477
    | Hs_Ensembl = ENSG00000140030
    | Hs_RefseqProtein = NP_003599
    | Hs_RefseqmRNA = NM_003608
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 14
    | Hs_GenLoc_start = 87541249
    | Hs_GenLoc_end = 87548164
    | Hs_Uniprot = Q8IYL9
    | Mm_EntrezGene = 14744
    | Mm_Ensembl = ENSMUSG00000021886
    | Mm_RefseqmRNA = NM_008152
    | Mm_RefseqProtein = NP_032178
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 12
    | Mm_GenLoc_start = 98669707
    | Mm_GenLoc_end = 98677682
    | Mm_Uniprot = Q3UQ35
  }}
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'''G protein-coupled receptor 65''', also known as '''GPR65''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR65 G protein-coupled receptor 65| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8477| accessdate = }}</ref>
 
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'''Psychosine receptor''' is a [[protein]] that in humans is encoded by the ''GPR65'' [[gene]].<ref name="pmid9655242">{{cite journal |vauthors=Kyaw H, Zeng Z, Su K, Fan P, Shell BK, Carter KC, Li Y | title = Cloning, characterization, and mapping of human homolog of mouse T-cell death-associated gene | journal = DNA Cell Biol | volume = 17 | issue = 6 | pages = 493–500 |date=Jul 1998 | pmid = 9655242 | pmc =  | doi =10.1089/dna.1998.17.493  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GPR65 G protein-coupled receptor 65| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8477| accessdate = }}</ref>
==See also==
*[[Proton-sensing G protein-coupled receptors]]


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Kyaw H, Zeng Z, Su K, ''et al.'' |title=Cloning, characterization, and mapping of human homolog of mouse T-cell death-associated gene. |journal=DNA Cell Biol. |volume=17 |issue= 6 |pages= 493-500 |year= 1998 |pmid= 9655242 |doi=  }}
*{{cite journal   |vauthors=Im DS, Heise CE, Nguyen T, etal |title=Identification of a Molecular Target of Psychosine and Its Role in Globoid Cell Formation |journal=J. Cell Biol. |volume=153 |issue= 2 |pages= 429–34 |year= 2001 |pmid= 11309421 |doi=10.1083/jcb.153.2.429  | pmc=2169470 }}
*{{cite journal  | author=Im DS, Heise CE, Nguyen T, ''et al.'' |title=Identification of a molecular target of psychosine and its role in globoid cell formation. |journal=J. Cell Biol. |volume=153 |issue= 2 |pages= 429-34 |year= 2001 |pmid= 11309421 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Heilig R, Eckenberg R, Petit JL, etal |title=The DNA sequence and analysis of human chromosome 14 |journal=Nature |volume=421 |issue= 6923 |pages= 601–7 |year= 2003 |pmid= 12508121 |doi= 10.1038/nature01348 }}
*{{cite journal | author=Heilig R, Eckenberg R, Petit JL, ''et al.'' |title=The DNA sequence and analysis of human chromosome 14. |journal=Nature |volume=421 |issue= 6923 |pages= 601-7 |year= 2003 |pmid= 12508121 |doi= 10.1038/nature01348 }}
*{{cite journal   |vauthors=Sin WC, Zhang Y, Zhong W, etal |title=G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers |journal=Oncogene |volume=23 |issue= 37 |pages= 6299–303 |year= 2004 |pmid= 15221007 |doi= 10.1038/sj.onc.1207838 }}
*{{cite journal | author=Sin WC, Zhang Y, Zhong W, ''et al.'' |title=G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers. |journal=Oncogene |volume=23 |issue= 37 |pages= 6299-303 |year= 2004 |pmid= 15221007 |doi= 10.1038/sj.onc.1207838 }}
*{{cite journal   |vauthors=Wang JQ, Kon J, Mogi C, etal |title=TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor |journal=J. Biol. Chem. |volume=279 |issue= 44 |pages= 45626–33 |year= 2004 |pmid= 15326175 |doi= 10.1074/jbc.M406966200 }}
*{{cite journal | author=Wang JQ, Kon J, Mogi C, ''et al.'' |title=TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor. |journal=J. Biol. Chem. |volume=279 |issue= 44 |pages= 45626-33 |year= 2004 |pmid= 15326175 |doi= 10.1074/jbc.M406966200 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  |vauthors=Ishii S, Kihara Y, Shimizu T |title=Identification of T cell death-associated gene 8 (TDAG8) as a novel acid sensing G-protein-coupled receptor |journal=J. Biol. Chem. |volume=280 |issue= 10 |pages= 9083–7 |year= 2005 |pmid= 15618224 |doi= 10.1074/jbc.M407832200 }}
*{{cite journal  | author=Ishii S, Kihara Y, Shimizu T |title=Identification of T cell death-associated gene 8 (TDAG8) as a novel acid sensing G-protein-coupled receptor. |journal=J. Biol. Chem. |volume=280 |issue= 10 |pages= 9083-7 |year= 2005 |pmid= 15618224 |doi= 10.1074/jbc.M407832200 }}
*{{cite journal   |vauthors=Radu CG, Nijagal A, McLaughlin J, etal |title=Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 5 |pages= 1632–7 |year= 2005 |pmid= 15665078 |doi= 10.1073/pnas.0409415102 | pmc=545089 }}
*{{cite journal | author=Radu CG, Nijagal A, McLaughlin J, ''et al.'' |title=Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 5 |pages= 1632-7 |year= 2005 |pmid= 15665078 |doi= 10.1073/pnas.0409415102 }}
}}
}}
{{refend}}
{{refend}}


{{{membrane-protein-stub}}
{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
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[[Category:G protein coupled receptors]]
[[Category:G protein coupled receptors]]
{{WikiDoc Sources}}
 
 
{{transmembranereceptor-stub}}

Revision as of 09:01, 31 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Psychosine receptor is a protein that in humans is encoded by the GPR65 gene.[1][2]

See also

References

  1. ↑ Kyaw H, Zeng Z, Su K, Fan P, Shell BK, Carter KC, Li Y (Jul 1998). "Cloning, characterization, and mapping of human homolog of mouse T-cell death-associated gene". DNA Cell Biol. 17 (6): 493–500. doi:10.1089/dna.1998.17.493. PMID 9655242.
  2. ↑ "Entrez Gene: GPR65 G protein-coupled receptor 65".

Further reading


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