Neuromedin U receptor 1: Difference between revisions

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{{Infobox_gene}}
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'''Neuromedin-U receptor 1''' is a [[protein]] that in humans is encoded by the ''NMUR1'' [[gene]].<ref name="pmid9782091">{{cite journal |vauthors=Tan CP, McKee KK, Liu Q, Palyha OC, Feighner SD, Hreniuk DL, Smith RG, Howard AD | title = Cloning and characterization of a human and murine T-cell orphan G-protein-coupled receptor similar to the growth hormone secretagogue and neurotensin receptors | journal = Genomics | volume = 52 | issue = 2 | pages = 223–9 |date=Dec 1998 | pmid = 9782091 | pmc =  | doi = 10.1006/geno.1998.5441 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NMUR1 neuromedin U receptor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10316| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Neuromedin U receptor 1
| HGNCid = 4518
| Symbol = NMUR1
| AltSymbols =; (FM-3); FM-3; FM3; GPC-R; GPR66; NMU1R
| OMIM = 604153
| ECnumber = 
| Homologene = 68501
| MGIid = 1341898
| GeneAtlas_image1 = PBB_GE_NMUR1_221383_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0001607 |text = neuromedin U receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}}
| Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0006816 |text = calcium ion transport}} {{GNF_GO|id=GO:0006821 |text = chloride transport}} {{GNF_GO|id=GO:0006939 |text = smooth muscle contraction}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007202 |text = phospholipase C activation}} {{GNF_GO|id=GO:0007218 |text = neuropeptide signaling pathway}} {{GNF_GO|id=GO:0019226 |text = transmission of nerve impulse}} {{GNF_GO|id=GO:0019722 |text = calcium-mediated signaling}} {{GNF_GO|id=GO:0045045 |text = secretory pathway}} {{GNF_GO|id=GO:0048016 |text = inositol phosphate-mediated signaling}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 10316
    | Hs_Ensembl = ENSG00000171596
    | Hs_RefseqProtein = NP_006047
    | Hs_RefseqmRNA = NM_006056
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 2
    | Hs_GenLoc_start = 232096116
    | Hs_GenLoc_end = 232103452
    | Hs_Uniprot = Q9HB89
    | Mm_EntrezGene = 14767
    | Mm_Ensembl = ENSMUSG00000026237
    | Mm_RefseqmRNA = NM_010341
    | Mm_RefseqProtein = NP_034471
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 1
    | Mm_GenLoc_start = 88217496
    | Mm_GenLoc_end = 88219312
    | Mm_Uniprot = Q0VB23
  }}
}}
'''Neuromedin U receptor 1''', also known as '''NMUR1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NMUR1 neuromedin U receptor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10316| accessdate = }}</ref>


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==See also==
==See also==
* [[Neuromedin U receptor]]
* [[Neuromedin U receptor]]
* [[Limostatin]]


==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
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{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Tan CP, McKee KK, Liu Q, ''et al.'' |title=Cloning and characterization of a human and murine T-cell orphan G-protein-coupled receptor similar to the growth hormone secretagogue and neurotensin receptors. |journal=Genomics |volume=52 |issue= 2 |pages= 223-9 |year= 1998 |pmid= 9782091 |doi= 10.1006/geno.1998.5441 }}
*{{cite journal   |vauthors=Fujii R, Hosoya M, Fukusumi S, etal |title=Identification of neuromedin U as the cognate ligand of the orphan G protein-coupled receptor FM-3. |journal=J. Biol. Chem. |volume=275 |issue= 28 |pages= 21068–74 |year= 2000 |pmid= 10783389 |doi= 10.1074/jbc.M001546200 }}
*{{cite journal  | author=Fujii R, Hosoya M, Fukusumi S, ''et al.'' |title=Identification of neuromedin U as the cognate ligand of the orphan G protein-coupled receptor FM-3. |journal=J. Biol. Chem. |volume=275 |issue= 28 |pages= 21068-74 |year= 2000 |pmid= 10783389 |doi= 10.1074/jbc.M001546200 }}
*{{cite journal   |vauthors=Szekeres PG, Muir AI, Spinage LD, etal |title=Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3. |journal=J. Biol. Chem. |volume=275 |issue= 27 |pages= 20247–50 |year= 2000 |pmid= 10811630 |doi= 10.1074/jbc.C000244200 }}
*{{cite journal | author=Szekeres PG, Muir AI, Spinage LD, ''et al.'' |title=Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3. |journal=J. Biol. Chem. |volume=275 |issue= 27 |pages= 20247-50 |year= 2000 |pmid= 10811630 |doi= 10.1074/jbc.C000244200 }}
*{{cite journal   |vauthors=Raddatz R, Wilson AE, Artymyshyn R, etal |title=Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system. |journal=J. Biol. Chem. |volume=275 |issue= 42 |pages= 32452–9 |year= 2000 |pmid= 10899166 |doi= 10.1074/jbc.M004613200 }}
*{{cite journal | author=Raddatz R, Wilson AE, Artymyshyn R, ''et al.'' |title=Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system. |journal=J. Biol. Chem. |volume=275 |issue= 42 |pages= 32452-9 |year= 2000 |pmid= 10899166 |doi= 10.1074/jbc.M004613200 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Mori K, Miyazato M, Ida T, etal |title=Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. |journal=EMBO J. |volume=24 |issue= 2 |pages= 325–35 |year= 2005 |pmid= 15635449 |doi= 10.1038/sj.emboj.7600526 | pmc=545815 }}
*{{cite journal | author=Mori K, Miyazato M, Ida T, ''et al.'' |title=Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. |journal=EMBO J. |volume=24 |issue= 2 |pages= 325-35 |year= 2005 |pmid= 15635449 |doi= 10.1038/sj.emboj.7600526 }}
*{{cite journal   |vauthors=Hillier LW, Graves TA, Fulton RS, etal |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466 }}
*{{cite journal | author=Hillier LW, Graves TA, Fulton RS, ''et al.'' |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724-31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466 }}
}}
}}
{{refend}}
{{refend}}


{{membrane-protein-stub}}
==External links==
*{{cite web | url = http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2894 | title = Neuromedin U Receptors: NMU1 | accessdate = | date = | format = | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | pages = | language = | archiveurl = | archivedate = | quote = }}
* {{UCSC genome browser|NMUR1}}
* {{UCSC gene details|NMUR1}}
 
{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
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[[Category:G protein coupled receptors]]
[[Category:G protein coupled receptors]]
{{WikiDoc Sources}}
 
 
{{transmembranereceptor-stub}}

Revision as of 15:51, 6 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Neuromedin-U receptor 1 is a protein that in humans is encoded by the NMUR1 gene.[1][2]


See also

References

  1. ↑ Tan CP, McKee KK, Liu Q, Palyha OC, Feighner SD, Hreniuk DL, Smith RG, Howard AD (Dec 1998). "Cloning and characterization of a human and murine T-cell orphan G-protein-coupled receptor similar to the growth hormone secretagogue and neurotensin receptors". Genomics. 52 (2): 223–9. doi:10.1006/geno.1998.5441. PMID 9782091.
  2. ↑ "Entrez Gene: NMUR1 neuromedin U receptor 1".

Further reading

External links


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