GPR78: Difference between revisions

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{{Infobox_gene}}
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'''Probable G-protein coupled receptor 78''' is a [[protein]] that in humans is encoded by the ''GPR78'' [[gene]].<ref name="pmid11574155">{{cite journal |vauthors=Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF | title = Discovery and mapping of ten novel G protein-coupled receptor genes | journal = Gene | volume = 275 | issue = 1 | pages = 83–91 |date=Sep 2001 | pmid = 11574155 | pmc =  | doi =10.1016/S0378-1119(01)00651-5 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GPR78 G protein-coupled receptor 78| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27201| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = G protein-coupled receptor 78
| HGNCid = 4528
| Symbol = GPR78
| AltSymbols =;
| OMIM = 606921
| ECnumber =
| Homologene = 50960
| MGIid =
  | Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 27201
    | Hs_Ensembl = ENSG00000155269
    | Hs_RefseqProtein = NP_543009
    | Hs_RefseqmRNA = NM_080819
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 4
    | Hs_GenLoc_start = 8633117
    | Hs_GenLoc_end = 8642647
    | Hs_Uniprot = Q96P69
    | Mm_EntrezGene = 
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = 
    | Mm_RefseqProtein = 
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
    | Mm_Uniprot = 
  }}
}}
'''G protein-coupled receptor 78''', also known as '''GPR78''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPR78 G protein-coupled receptor 78| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27201| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: GPR78 G protein-coupled receptor 78| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27201| accessdate = }}</ref>
| summary_text = G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM]<ref name="entrez" />
}}
}}


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=van Laar T, Schouten T, Hoogervorst E, ''et al.'' |title=The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway. |journal=FEBS Lett. |volume=469 |issue= 1 |pages= 123-31 |year= 2000 |pmid= 10708769 |doi=  }}
*{{cite journal  | author=van Laar T |title=The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway |journal=FEBS Lett. |volume=469 |issue= 1 |pages= 123–31 |year= 2000 |pmid= 10708769 |doi=10.1016/S0014-5793(00)01253-9 |name-list-format=vanc| author2=Schouten T | author3=Hoogervorst E  | display-authors=3  | last4=Van Eck  | first4=M  | last5=Van Der Eb  | first5=AJ  | last6=Terleth  | first6=C }}
*{{cite journal  | author=Lee DK, Nguyen T, Lynch KR, ''et al.'' |title=Discovery and mapping of ten novel G protein-coupled receptor genes. |journal=Gene |volume=275 |issue= 1 |pages= 83-91 |year= 2001 |pmid= 11574155 |doi=  }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Clark HF |title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697  |name-list-format=vanc| author2=Gurney AL  | author3=Abaya E  | display-authors=3  | last4=Baker  | first4=K  | last5=Baldwin  | first5=D  | last6=Brush  | first6=J  | last7=Chen  | first7=J  | last8=Chow  | first8=B  | last9=Chui  | first9=C }}
*{{cite journal  | author=Clark HF, Gurney AL, Abaya E, ''et al.'' |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265-70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Underwood SL |title=Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia |journal=Mol. Psychiatry |volume=11 |issue= 4 |pages= 384–94 |year= 2006 |pmid= 16389273 |doi= 10.1038/sj.mp.4001786 |name-list-format=vanc| author2=Christoforou A  | author3=Thomson PA  | display-authors=3  | last4=Wray  | first4=N R  | last5=Tenesa  | first5=A  | last6=Whittaker  | first6=J  | last7=Adams  | first7=R A  | last8=Le Hellard  | first8=S  | last9=Morris  | first9=S W }}
*{{cite journal  | author=Underwood SL, Christoforou A, Thomson PA, ''et al.'' |title=Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia. |journal=Mol. Psychiatry |volume=11 |issue= 4 |pages= 384-94 |year= 2006 |pmid= 16389273 |doi= 10.1038/sj.mp.4001786 }}
}}
}}
{{refend}}
{{refend}}


{{membrane-protein-stub}}
{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
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[[Category:G protein coupled receptors]]
[[Category:G protein coupled receptors]]
{{WikiDoc Sources}}
 
 
{{transmembranereceptor-stub}}

Revision as of 09:01, 31 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Probable G-protein coupled receptor 78 is a protein that in humans is encoded by the GPR78 gene.[1][2]

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM][2]

References

  1. ↑ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.
  2. ↑ 2.0 2.1 "Entrez Gene: GPR78 G protein-coupled receptor 78".

Further reading


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