LGR5

Leucine-rich repeat-containing G protein-coupled receptor 5
Identifiers
Symbols	LGR5 ; FEX; GPR49; GPR67; GRP49; HG38; MGC117008
External IDs	Template:OMIM5 Template:MGI HomoloGene: 20807
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE LGR5 213880 at tn.png
File:PBB GE LGR5 210393 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Leucine-rich repeat-containing G protein-coupled receptor 5, also known as LGR5, is a human gene.

Further reading

• McDonald T, Wang R, Bailey W; et al. (1998). "Identification and cloning of an orphan G protein-coupled receptor of the glycoprotein hormone receptor subfamily". Biochem. Biophys. Res. Commun. 247 (2): 266–70. doi:10.1006/bbrc.1998.8774. PMID 9642114.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hsu SY, Liang SG, Hsueh AJ (1999). "Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region". Mol. Endocrinol. 12 (12): 1830–45. PMID 9849958.CS1 maint: Multiple names: authors list (link)
• Hsu SY, Kudo M, Chen T; et al. (2001). "The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7". Mol. Endocrinol. 14 (8): 1257–71. PMID 10935549.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yamamoto Y, Sakamoto M, Fujii G; et al. (2003). "Overexpression of orphan G-protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with beta-catenin mutations". Hepatology. 37 (3): 528–33. doi:10.1053/jhep.2003.50029. PMID 12601349.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• McClanahan T, Koseoglu S, Smith K; et al. (2007). "Identification of overexpression of orphan G protein-coupled receptor GPR49 in human colon and ovarian primary tumors". Cancer Biol. Ther. 5 (4): 419–26. PMID 16575208.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.