Melanocortin 5 receptor

Melanocortin 5 receptor
Identifiers
Symbols	MC5R ;
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4321
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE MC5R 208565 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Melanocortin 5 receptor, also known as MC5R, is a human gene. It is located on the chromosome 18 in the human genome. When the melanocortin 5 receptor was disrupted in transgenic mice, it induced disruption of their exocrine glands and resulted in decreased production of sebum.

See also

• Melanocortin receptor

Further reading

• Fathi Z, Iben LG, Parker EM (1995). "Cloning, expression, and tissue distribution of a fifth melanocortin receptor subtype". Neurochem. Res. 20 (1): 107–13. PMID 7739752.CS1 maint: Multiple names: authors list (link)
• Chowdhary BP, Gustavsson I, Wikberg JE, Chhajlani V (1994). "Localization of the human melanocortin-5 receptor gene (MC5R) to chromosome band 18p11.2 by fluorescence in situ hybridization". Cytogenet. Cell Genet. 68 (1–2): 79–81. PMID 7956366.CS1 maint: Multiple names: authors list (link)
• Griffon N, Mignon V, Facchinetti P; et al. (1994). "Molecular cloning and characterization of the rat fifth melanocortin receptor". Biochem. Biophys. Res. Commun. 200 (2): 1007–14. PMID 8179577.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gantz I, Shimoto Y, Konda Y; et al. (1994). "Molecular cloning, expression, and characterization of a fifth melanocortin receptor". Biochem. Biophys. Res. Commun. 200 (3): 1214–20. doi:10.1006/bbrc.1994.1580. PMID 8185570.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chhajlani V, Muceniece R, Wikberg JE (1993). "Molecular cloning of a novel human melanocortin receptor". Biochem. Biophys. Res. Commun. 195 (2): 866–73. doi:10.1006/bbrc.1993.2125. PMID 8396929.CS1 maint: Multiple names: authors list (link)
• Chhajlani V (1997). "Distribution of cDNA for melanocortin receptor subtypes in human tissues". Biochem. Mol. Biol. Int. 38 (1): 73–80. PMID 8932521.
• Yang YK, Ollmann MM, Wilson BD; et al. (1997). "Effects of recombinant agouti-signaling protein on melanocortin action". Mol. Endocrinol. 11 (3): 274–80. PMID 9058374.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Frändberg PA, Xu X, Chhajlani V (1997). "Glutamine235 and arginine272 in human melanocortin 5 receptor determines its low affinity to MSH". Biochem. Biophys. Res. Commun. 236 (2): 489–92. doi:10.1006/bbrc.1997.6994. PMID 9240466.CS1 maint: Multiple names: authors list (link)
• Yang YK, Thompson DA, Dickinson CJ; et al. (1999). "Characterization of Agouti-related protein binding to melanocortin receptors". Mol. Endocrinol. 13 (1): 148–55. PMID 9892020.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hatta N, Dixon C, Ray AJ; et al. (2001). "Expression, candidate gene, and population studies of the melanocortin 5 receptor". J. Invest. Dermatol. 116 (4): 564–70. doi:10.1046/j.0022-202x.2001.01286.x. PMID 11286624.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bednarek MA, MacNeil T, Kalyani RN; et al. (2001). "Selective, high affinity peptide antagonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro". J. Med. Chem. 44 (22): 3665–72. PMID 11606131.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lapinsh M, Veiksina S, Uhlén S; et al. (2005). "Proteochemometric mapping of the interaction of organic compounds with melanocortin receptor subtypes". Mol. Pharmacol. 67 (1): 50–9. doi:10.1124/mol.104.002857. PMID 15470082.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lohoff FW, Berrettini WH (2006). "Lack of association between variations in the melanocortin 5 receptor gene and bipolar disorder". Psychiatr. Genet. 15 (4): 255–8. PMID 16314755.
• Grieco P, Cai M, Han G; et al. (2007). "Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5". Peptides. 28 (6): 1191–6. doi:10.1016/j.peptides.2007.02.012. PMID 17482720.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.