Galanin receptor 3
Galanin receptor 3 | |||||||||||
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Identifiers | |||||||||||
Symbols | GALR3 ; | ||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 20798 | ||||||||||
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RNA expression pattern | |||||||||||
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Species | Human | Mouse | |||||||||
Entrez | n/a | n/a | |||||||||
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RefSeq (mRNA) | n/a | n/a | |||||||||
RefSeq (protein) | n/a | n/a | |||||||||
Location (UCSC) | n/a | n/a | |||||||||
PubMed search | n/a | n/a |
Galanin receptor 3, also known as GALR3, is a human gene.[1]
The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts[1]
See also
References
Further reading
- Smith KE, Walker MW, Artymyshyn R; et al. (1998). "Cloned human and rat galanin GALR3 receptors. Pharmacology and activation of G-protein inwardly rectifying K+ channels". J. Biol. Chem. 273 (36): 23321–6. PMID 9722565.
- Kolakowski LF, O'Neill GP, Howard AD; et al. (1998). "Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3". J. Neurochem. 71 (6): 2239–51. PMID 9832121.
- Iismaa TP, Fathi Z, Hort YJ; et al. (1999). "Structural organization and chromosomal localization of three human galanin receptor genes". Ann. N. Y. Acad. Sci. 863: 56–63. PMID 9928159.
- Lapsys NM, Furler SM, Henderson NK; et al. (1999). "A polymorphism in the human GALR3 galanin receptor gene (GALNR3)". Mol. Cell. Probes. 13 (4): 325–7. doi:10.1006/mcpr.1999.0254. PMID 10441207.
- Dunham I, Shimizu N, Roe BA; et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
- Berger A, Tuechler C, Almer D; et al. (2002). "Elevated expression of galanin receptors in childhood neuroblastic tumors". Neuroendocrinology. 75 (2): 130–8. PMID 11867941.
- Belfer I, Hipp H, Bollettino A; et al. (2007). "Alcoholism is associated with GALR3 but not two other galanin receptor genes". Genes Brain Behav. 6 (5): 473–81. doi:10.1111/j.1601-183X.2006.00275.x. PMID 17083333.
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.