Apelin receptor
| angiotensin II receptor-like 1 | |
|---|---|
| Identifiers | |
| Symbol | AGTRL1 |
| Alt. symbols | APJ, FLJ90771 |
| Entrez | 187 |
| HUGO | 339 |
| OMIM | 600052 |
| RefSeq | NM_005161 |
| UniProt | P35414 |
| Other data | |
| Locus | Chr. 11 q12 |
The apelin receptor (also known as the APJ receptor) is a G protein-coupled receptor[1] which binds apelin.[2][3][4]
References
- ↑ O'Dowd BF, Heiber M, Chan A, Heng HH, Tsui LC, Kennedy JL, Shi X, Petronis A, George SR, Nguyen T (1993). "A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11". Gene. 136 (1–2): 355–60. PMID 8294032.
- ↑ Tatemoto K, Hosoya M, Habata Y, Fujii R, Kakegawa T, Zou MX, Kawamata Y, Fukusumi S, Hinuma S, Kitada C, Kurokawa T, Onda H, Fujino M (1998). "Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor". Biochem. Biophys. Res. Commun. 251 (2): 471–6. doi:10.1006/bbrc.1998.9489. PMID 9792798.
- ↑ Lee DK, Cheng R, Nguyen T, Fan T, Kariyawasam AP, Liu Y, Osmond DH, George SR, O'Dowd BF (2000). "Characterization of apelin, the ligand for the APJ receptor". J. Neurochem. 74 (1): 34–41. PMID 10617103.
- ↑ Szokodi I, Tavi P, Földes G, Voutilainen-Myllylä S, Ilves M, Tokola H, Pikkarainen S, Piuhola J, Rysä J, Tóth M, Ruskoaho H (2002). "Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility". Circ. Res. 91 (5): 434–40. PMID 12215493.
External links
- IUPHAR GPCR Database - Apelin receptor
- Apelin+receptor,+human at the US National Library of Medicine Medical Subject Headings (MeSH)