EMR1
Egf-like module containing, mucin-like, hormone receptor-like 1 | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||||
Symbols | EMR1 ; TM7LN3 | ||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 1493 | ||||||||||
| |||||||||||
RNA expression pattern | |||||||||||
More reference expression data | |||||||||||
Orthologs | |||||||||||
Template:GNF Ortholog box | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | n/a | n/a | |||||||||
Ensembl | n/a | n/a | |||||||||
UniProt | n/a | n/a | |||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||
RefSeq (protein) | n/a | n/a | |||||||||
Location (UCSC) | n/a | n/a | |||||||||
PubMed search | n/a | n/a |
Egf-like module containing, mucin-like, hormone receptor-like 1, also known as EMR1, is a human gene.[1]
This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties.[1]
See also
References
Further reading
- McKnight AJ, Gordon S (1998). "The EGF-TM7 family: unusual structures at the leukocyte surface". J. Leukoc. Biol. 63 (3): 271–80. PMID 9500513.
- Baud V, Chissoe SL, Viegas-Péquignot E; et al. (1995). "EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments". Genomics. 26 (2): 334–44. PMID 7601460.
- McKnight AJ, Macfarlane AJ, Seldin MF, Gordon S (1998). "Chromosome mapping of the Emr1 gene". Mamm. Genome. 8 (12): 946. PMID 9383301.
- Carver EA, Hamann J, Olsen AS, Stubbs L (2000). "Physical mapping of EMR1 and CD97 in human Chromosome 19 and assignment of Cd97 to mouse Chromosome 8 suggest an ancient genomic duplication". Mamm. Genome. 10 (10): 1039–40. PMID 10501980.
- Lin HH, Stacey M, Hamann J; et al. (2000). "Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97". Genomics. 67 (2): 188–200. doi:10.1006/geno.2000.6238. PMID 10903844.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.