GPR50
G protein-coupled receptor 50 | |||||||||||
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Identifiers | |||||||||||
Symbols | GPR50 ; H9; MGC125342 | ||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 3113 | ||||||||||
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RNA expression pattern | |||||||||||
More reference expression data | |||||||||||
Orthologs | |||||||||||
Template:GNF Ortholog box | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | n/a | n/a | |||||||||
Ensembl | n/a | n/a | |||||||||
UniProt | n/a | n/a | |||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||
RefSeq (protein) | n/a | n/a | |||||||||
Location (UCSC) | n/a | n/a | |||||||||
PubMed search | n/a | n/a |
G protein-coupled receptor 50, also known as GPR50, is a human gene.[1]
References
Further reading
- Reppert SM, Weaver DR, Ebisawa T; et al. (1996). "Cloning of a melatonin-related receptor from human pituitary". FEBS Lett. 386 (2–3): 219–24. PMID 8647286.
- Gubitz AK, Reppert SM (1999). "Assignment of the melatonin-related receptor to human chromosome X (GPR50) and mouse chromosome X (Gpr50)". Genomics. 55 (2): 248–51. doi:10.1006/geno.1998.5661. PMID 9933574.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Slominski A, Pisarchik A, Zbytek B; et al. (2003). "Functional activity of serotoninergic and melatoninergic systems expressed in the skin". J. Cell. Physiol. 196 (1): 144–53. doi:10.1002/jcp.10287. PMID 12767050.
- Suzuki Y, Yamashita R, Shirota M; et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMID 15342556.
- Thomson PA, Wray NR, Thomson AM; et al. (2005). "Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor". Mol. Psychiatry. 10 (5): 470–8. doi:10.1038/sj.mp.4001593. PMID 15452587.
- Bhattacharyya S, Luan J, Challis B; et al. (2006). "Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels". J. Lipid Res. 47 (4): 761–6. doi:10.1194/jlr.M500338-JLR200. PMID 16436372.
- Levoye A, Dam J, Ayoub MA; et al. (2006). "The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization". EMBO J. 25 (13): 3012–23. doi:10.1038/sj.emboj.7601193. PMID 16778767.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.