GPRC6A
G protein-coupled receptor, family C, group 6, member A | |||||||||||
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Identifiers | |||||||||||
Symbols | GPRC6A ; GPCR; bA86F4.3 | ||||||||||
External IDs | Template:MGI HomoloGene: 17529 | ||||||||||
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Orthologs | |||||||||||
Template:GNF Ortholog box | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | n/a | n/a | |||||||||
Ensembl | n/a | n/a | |||||||||
UniProt | n/a | n/a | |||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||
RefSeq (protein) | n/a | n/a | |||||||||
Location (UCSC) | n/a | n/a | |||||||||
PubMed search | n/a | n/a |
G protein-coupled receptor, family C, group 6, member A, also known as GPRC6A, is a human gene.[1] This receptor functions as a sensor of L-amino acids.[2]
References
- ↑ "Entrez Gene: GPRC6A G protein-coupled receptor, family C, group 6, member A".
- ↑ Wellendorph P, Hansen KB, Balsgaard A, Greenwood JR, Egebjerg J, Bräuner-Osborne H (2005). "Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids". Mol. Pharmacol. 67 (3): 589–97. doi:10.1124/mol.104.007559. PMID 15576628.
Further reading
- Harrington JJ, Sherf B, Rundlett S; et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression". Nat. Biotechnol. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013.
- Takeda S, Kadowaki S, Haga T; et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. PMID 12044878.
- Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
- Wellendorph P, Bräuner-Osborne H (2004). "Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor". Gene. 335: 37–46. doi:10.1016/j.gene.2004.03.003. PMID 15194188.
- Wellendorph P, Hansen KB, Balsgaard A; et al. (2005). "Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids". Mol. Pharmacol. 67 (3): 589–97. doi:10.1124/mol.104.007559. PMID 15576628.
- Pi M, Faber P, Ekema G; et al. (2006). "Identification of a novel extracellular cation-sensing G-protein-coupled receptor". J. Biol. Chem. 280 (48): 40201–9. doi:10.1074/jbc.M505186200. PMID 16199532.
External links
- IUPHAR GPCR Database - GPRC6
- GPRC6A+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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