TAS2R50

Taste receptor, type 2, member 50
Identifiers
Symbols	TAS2R50 ; MGC138305; T2R51
External IDs	Template:OMIM5 HomoloGene: 88474
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Taste receptor, type 2, member 50, also known as TAS2R50, is a human gene.

TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002). See also TAS2R10 (MIM 604791).[supplied by OMIM]

See also

• Taste receptor

Further reading

• Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
• Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. PMID 12139982.
• Bufe B, Hofmann T, Krautwurst D; et al. (2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat. Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhang Y, Hoon MA, Chandrashekar J; et al. (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. PMID 12581520.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Conte C, Ebeling M, Marcuz A; et al. (2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet. Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.CS1 maint: Multiple names: authors list (link)
• Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMID 15744053.CS1 maint: Multiple names: authors list (link)
• Shiffman D, Ellis SG, Rowland CM; et al. (2005). "Identification of four gene variants associated with myocardial infarction". Am. J. Hum. Genet. 77 (4): 596–605. doi:10.1086/491674. PMID 16175505.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.