Formyl peptide receptor-like 1

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Formyl peptide receptor-like 1
Identifiers
Symbols FPRL1 ; ALXR; FMLP-R-II; FMLPX; FPR2A; FPRH1; FPRH2; HM63; LXA4R
External IDs Template:OMIM5 Template:MGI HomoloGene: 74395
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Formyl peptide receptor-like 1, also known as FPRL1, is a human gene.[1]


See also

References

  1. ↑ "Entrez Gene: FPRL1 Formyl peptide receptor-like 1".

Further reading

  • Murphy PM, Ozçelik T, Kenney RT; et al. (1992). "A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family". J. Biol. Chem. 267 (11): 7637–43. PMID 1373134.
  • Ye RD, Cavanagh SL, Quehenberger O; et al. (1992). "Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor". Biochem. Biophys. Res. Commun. 184 (2): 582–9. PMID 1374236.
  • Perez HD, Holmes R, Kelly E; et al. (1992). "Cloning of a cDNA encoding a receptor related to the formyl peptide receptor of human neutrophils". Gene. 118 (2): 303–4. PMID 1511907.
  • Bao L, Gerard NP, Eddy RL; et al. (1992). "Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19". Genomics. 13 (2): 437–40. PMID 1612600.
  • Nomura H, Nielsen BW, Matsushima K (1994). "Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors". Int. Immunol. 5 (10): 1239–49. PMID 7505609.
  • Durstin M, Gao JL, Tiffany HL; et al. (1994). "Differential expression of members of the N-formylpeptide receptor gene cluster in human phagocytes". Biochem. Biophys. Res. Commun. 201 (1): 174–9. doi:10.1006/bbrc.1994.1685. PMID 8198572.
  • Maddox JF, Hachicha M, Takano T; et al. (1997). "Lipoxin A4 stable analogs are potent mimetics that stimulate human monocytes and THP-1 cells via a G-protein-linked lipoxin A4 receptor". J. Biol. Chem. 272 (11): 6972–8. PMID 9054386.
  • Takano T, Fiore S, Maddox JF; et al. (1997). "Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors". J. Exp. Med. 185 (9): 1693–704. PMID 9151906.
  • Gronert K, Gewirtz A, Madara JL, Serhan CN (1998). "Identification of a human enterocyte lipoxin A4 receptor that is regulated by interleukin (IL)-13 and interferon gamma and inhibits tumor necrosis factor alpha-induced IL-8 release". J. Exp. Med. 187 (8): 1285–94. PMID 9547339.
  • Deng X, Ueda H, Su SB; et al. (1999). "A synthetic peptide derived from human immunodeficiency virus type 1 gp120 downregulates the expression and function of chemokine receptors CCR5 and CXCR4 in monocytes by activating the 7-transmembrane G-protein-coupled receptor FPRL1/LXA4R". Blood. 94 (4): 1165–73. PMID 10438703.
  • Chiang N, Fierro IM, Gronert K, Serhan CN (2000). "Activation of lipoxin A(4) receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation". J. Exp. Med. 191 (7): 1197–208. PMID 10748237.
  • Shen W, Proost P, Li B; et al. (2000). "Activation of the chemotactic peptide receptor FPRL1 in monocytes phosphorylates the chemokine receptor CCR5 and attenuates cell responses to selected chemokines". Biochem. Biophys. Res. Commun. 272 (1): 276–83. doi:10.1006/bbrc.2000.2770. PMID 10872839.
  • Le Y, Jiang S, Hu J; et al. (2000). "N36, a synthetic N-terminal heptad repeat domain of the HIV-1 envelope protein gp41, is an activator of human phagocytes". Clin. Immunol. 96 (3): 236–42. doi:10.1006/clim.2000.4896. PMID 10964542.
  • De Yang , Chen Q, Schmidt AP; et al. (2000). "LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells". J. Exp. Med. 192 (7): 1069–74. PMID 11015447.
  • Kang Y, Taddeo B, Varai G; et al. (2000). "Mutations of serine 236-237 and tyrosine 302 residues in the human lipoxin A4 receptor intracellular domains result in sustained signaling". Biochemistry. 39 (44): 13551–7. PMID 11063592.
  • Svensson L, Dahlgren C, Wennerås C (2002). "The chemoattractant Trp-Lys-Tyr-Met-Val-D-Met activates eosinophils through the formyl peptide receptor and one of its homologues, formyl peptide receptor-like 1". J. Leukoc. Biol. 72 (4): 810–8. PMID 12377951.
  • He R, Sang H, Ye RD (2003). "Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R". Blood. 101 (4): 1572–81. doi:10.1182/blood-2002-05-1431. PMID 12393391.
  • Christophe T, Karlsson A, Rabiet MJ; et al. (2002). "Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4". Scand. J. Immunol. 56 (5): 470–6. PMID 12410796.
  • Kucharzik T, Gewirtz AT, Merlin D; et al. (2003). "Lateral membrane LXA4 receptors mediate LXA4's anti-inflammatory actions on intestinal epithelium". Am. J. Physiol., Cell Physiol. 284 (4): C888–96. doi:10.1152/ajpcell.00507.2001. PMID 12456400.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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