GPR92
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G protein-coupled receptor 92 | |||||||||||
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Identifiers | |||||||||||
Symbols | GPR92 ; GPR93; KPG_010; LPA5; LPAR5 | ||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 10696 | ||||||||||
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Orthologs | |||||||||||
Template:GNF Ortholog box | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | n/a | n/a | |||||||||
Ensembl | n/a | n/a | |||||||||
UniProt | n/a | n/a | |||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||
RefSeq (protein) | n/a | n/a | |||||||||
Location (UCSC) | n/a | n/a | |||||||||
PubMed search | n/a | n/a |
G protein-coupled receptor 92, also known as GPR92, is a human gene.[1]
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM][1]
References
Further reading
- "Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23". Nat. Genet. 26 (3): 345–8. 2000. doi:10.1038/81664. PMID 11062477.
- Lee DK, Nguyen T, Lynch KR; et al. (2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. PMID 11574155.
- Takeda S, Kadowaki S, Haga T; et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. PMID 12044878.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Kotarsky K, Boketoft A, Bristulf J; et al. (2006). "Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastrointestinal lymphocytes". J. Pharmacol. Exp. Ther. 318 (2): 619–28. doi:10.1124/jpet.105.098848. PMID 16651401.
- Lee CW, Rivera R, Gardell S; et al. (2006). "GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5". J. Biol. Chem. 281 (33): 23589–97. doi:10.1074/jbc.M603670200. PMID 16774927.
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