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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Somatostatin receptor type 4''' is a [[protein]] that in humans is encoded by the ''SSTR4'' [[gene]].<ref name="pmid8483934">{{cite journal | vauthors = Rohrer L, Raulf F, Bruns C, Buettner R, Hofstaedter F, Schüle R | title = Cloning and characterization of a fourth human somatostatin receptor | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 90 | issue = 9 | pages = 4196–200 | date = May 1993 | pmid = 8483934 | pmc = 46473 | doi = 10.1073/pnas.90.9.4196 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SSTR4 somatostatin receptor 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6754| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
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| update_citations = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Somatostatin receptor 4
| HGNCid = 11333
| Symbol = SSTR4
| AltSymbols =;
| OMIM = 182454
| ECnumber = 
| Homologene = 20286
| MGIid = 105372
| GeneAtlas_image1 = PBB_GE_SSTR4_214556_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004994 |text = somatostatin receptor activity}} {{GNF_GO|id=GO:0030273 |text = melanin-concentrating hormone receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007187 |text = G-protein signaling, coupled to cyclic nucleotide second messenger}} {{GNF_GO|id=GO:0007218 |text = neuropeptide signaling pathway}} {{GNF_GO|id=GO:0008285 |text = negative regulation of cell proliferation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6754
    | Hs_Ensembl = ENSG00000132671
    | Hs_RefseqProtein = NP_001043
    | Hs_RefseqmRNA = NM_001052
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 20
    | Hs_GenLoc_start = 22964023
    | Hs_GenLoc_end = 22965449
    | Hs_Uniprot = P31391
    | Mm_EntrezGene = 20608
    | Mm_Ensembl = ENSMUSG00000037014
    | Mm_RefseqmRNA = NM_009219
    | Mm_RefseqProtein = NP_033245
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 2
    | Mm_GenLoc_start = 148086783
    | Mm_GenLoc_end = 148092384
    | Mm_Uniprot = Q8BQ97
  }}
}}
'''Somatostatin receptor 4''', also known as '''SSTR4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SSTR4 somatostatin receptor 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6754| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins.  The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner.  SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung.<ref name="entrez" />
{{PBB_Summary
| section_title =
| summary_text = Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins.  The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner.  SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung.<ref name="entrez">{{cite web | title = Entrez Gene: SSTR4 somatostatin receptor 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6754| accessdate = }}</ref>
}}


==See also==
== See also ==
* [[Somatostatin receptor]]
* [[Somatostatin receptor]]


==References==
== References ==
{{reflist|2}}
{{reflist}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Patel YC | title = Somatostatin and its receptor family | journal = Frontiers in Neuroendocrinology | volume = 20 | issue = 3 | pages = 157–98 | date = July 1999 | pmid = 10433861 | doi = 10.1006/frne.1999.0183 }}
| citations =
* {{cite journal | vauthors = Yamada Y, Post SR, Wang K, Tager HS, Bell GI, Seino S | title = Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 89 | issue = 1 | pages = 251–5 | date = January 1992 | pmid = 1346068 | pmc = 48214 | doi = 10.1073/pnas.89.1.251 }}
*{{cite journal | author=Patel YC |title=Somatostatin and its receptor family. |journal=Frontiers in neuroendocrinology |volume=20 |issue= 3 |pages= 157-98 |year= 1999 |pmid= 10433861 |doi= 10.1006/frne.1999.0183 }}
* {{cite journal | vauthors = Demchyshyn LL, Srikant CB, Sunahara RK, Kent G, Seeman P, Van Tol HH, Panetta R, Patel YC, Niznik HB | title = Cloning and expression of a human somatostatin-14-selective receptor variant (somatostatin receptor 4) located on chromosome 20 | journal = Molecular Pharmacology | volume = 43 | issue = 6 | pages = 894–901 | date = June 1993 | pmid = 8100352 | doi =  }}
*{{cite journal | author=Yamada Y, Post SR, Wang K, ''et al.'' |title=Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 1 |pages= 251-5 |year= 1992 |pmid= 1346068 |doi= }}
* {{cite journal | vauthors = Yasuda K, Espinosa R, Davis EM, Le Beau MM, Bell GI | title = Human somatostatin receptor genes: localization of SSTR5 to human chromosome 20p11.2 | journal = Genomics | volume = 17 | issue = 3 | pages = 785–6 | date = September 1993 | pmid = 8244401 | doi = 10.1006/geno.1993.1410 }}
*{{cite journal | author=Demchyshyn LL, Srikant CB, Sunahara RK, ''et al.'' |title=Cloning and expression of a human somatostatin-14-selective receptor variant (somatostatin receptor 4) located on chromosome 20. |journal=Mol. Pharmacol. |volume=43 |issue= 6 |pages= 894-901 |year= 1993 |pmid= 8100352 |doi=  }}
* {{cite journal | vauthors = Yamada Y, Kagimoto S, Kubota A, Yasuda K, Masuda K, Someya Y, Ihara Y, Li Q, Imura H, Seino S | title = Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype | journal = Biochemical and Biophysical Research Communications | volume = 195 | issue = 2 | pages = 844–52 | date = September 1993 | pmid = 8373420 | doi = 10.1006/bbrc.1993.2122 }}
*{{cite journal | author=Yasuda K, Espinosa R, Davis EM, ''et al.'' |title=Human somatostatin receptor genes: localization of SSTR5 to human chromosome 20p11.2. |journal=Genomics |volume=17 |issue= 3 |pages= 785-6 |year= 1993 |pmid= 8244401 |doi= 10.1006/geno.1993.1410 }}
* {{cite journal | vauthors = Kaupmann K, Bruns C, Hoyer D, Seuwen K, Lübbert H | title = Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain | journal = FEBS Letters | volume = 331 | issue = 1-2 | pages = 53–9 | date = September 1993 | pmid = 8405411 | doi = 10.1016/0014-5793(93)80296-7 }}
*{{cite journal | author=Yamada Y, Kagimoto S, Kubota A, ''et al.'' |title=Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype. |journal=Biochem. Biophys. Res. Commun. |volume=195 |issue= 2 |pages= 844-52 |year= 1993 |pmid= 8373420 |doi= }}
* {{cite journal | vauthors = Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI | title = Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms | journal = Genomics | volume = 15 | issue = 2 | pages = 449–52 | date = February 1993 | pmid = 8449518 | doi = 10.1006/geno.1993.1088 }}
*{{cite journal | author=Kaupmann K, Bruns C, Hoyer D, ''et al.'' |title=Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain. |journal=FEBS Lett. |volume=331 |issue= 1-2 |pages= 53-9 |year= 1993 |pmid= 8405411 |doi= }}
* {{cite journal | vauthors = Xu Y, Song J, Bruno JF, Berelowitz M | title = Molecular cloning and sequencing of a human somatostatin receptor, hSSTR4 | journal = Biochemical and Biophysical Research Communications | volume = 193 | issue = 2 | pages = 648–52 | date = June 1993 | pmid = 8512564 | doi = 10.1006/bbrc.1993.1673 }}
*{{cite journal | author=Yamada Y, Stoffel M, Espinosa R, ''et al.'' |title=Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms. |journal=Genomics |volume=15 |issue= 2 |pages= 449-52 |year= 1993 |pmid= 8449518 |doi= 10.1006/geno.1993.1088 }}
* {{cite journal | vauthors = Fukusumi S, Kitada C, Takekawa S, Kizawa H, Sakamoto J, Miyamoto M, Hinuma S, Kitano K, Fujino M | title = Identification and characterization of a novel human cortistatin-like peptide | journal = Biochemical and Biophysical Research Communications | volume = 232 | issue = 1 | pages = 157–63 | date = March 1997 | pmid = 9125122 | doi = 10.1006/bbrc.1997.6252 }}
*{{cite journal | author=Rohrer L, Raulf F, Bruns C, ''et al.'' |title=Cloning and characterization of a fourth human somatostatin receptor. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 9 |pages= 4196-200 |year= 1993 |pmid= 8483934 |doi=  }}
* {{cite journal | vauthors = de Lecea L, Ruiz-Lozano P, Danielson PE, Peelle-Kirley J, Foye PE, Frankel WN, Sutcliffe JG | title = Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin | journal = Genomics | volume = 42 | issue = 3 | pages = 499–506 | date = June 1997 | pmid = 9205124 | doi = 10.1006/geno.1997.4763 }}
*{{cite journal  | author=Xu Y, Song J, Bruno JF, Berelowitz M |title=Molecular cloning and sequencing of a human somatostatin receptor, hSSTR4. |journal=Biochem. Biophys. Res. Commun. |volume=193 |issue= 2 |pages= 648-52 |year= 1993 |pmid= 8512564 |doi= }}
* {{cite journal | vauthors = Jaïs P, Terris B, Ruszniewski P, LeRomancer M, Reyl-Desmars F, Vissuzaine C, Cadiot G, Mignon M, Lewin MJ | title = Somatostatin receptor subtype gene expression in human endocrine gastroentero-pancreatic tumours | journal = European Journal of Clinical Investigation | volume = 27 | issue = 8 | pages = 639–44 | date = August 1997 | pmid = 9279525 | doi = 10.1046/j.1365-2362.1997.1740719.x }}
*{{cite journal | author=Fukusumi S, Kitada C, Takekawa S, ''et al.'' |title=Identification and characterization of a novel human cortistatin-like peptide. |journal=Biochem. Biophys. Res. Commun. |volume=232 |issue= 1 |pages= 157-63 |year= 1997 |pmid= 9125122 |doi= 10.1006/bbrc.1997.6252 }}
* {{cite journal | vauthors = Sharma K, Patel YC, Srikant CB | title = C-terminal region of human somatostatin receptor 5 is required for induction of Rb and G1 cell cycle arrest | journal = Molecular Endocrinology | volume = 13 | issue = 1 | pages = 82–90 | date = January 1999 | pmid = 9892014 | doi = 10.1210/me.13.1.82 }}
*{{cite journal | author=de Lecea L, Ruiz-Lozano P, Danielson PE, ''et al.'' |title=Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin. |journal=Genomics |volume=42 |issue= 3 |pages= 499-506 |year= 1997 |pmid= 9205124 |doi= 10.1006/geno.1997.4763 }}
* {{cite journal | vauthors = Forssell-Aronsson EB, Nilsson O, Bejegård SA, Kölby L, Bernhardt P, Mölne J, Hashemi SH, Wängberg B, Tisell LE, Ahlman H | title = 111In-DTPA-D-Phe1-octreotide binding and somatostatin receptor subtypes in thyroid tumors | journal = Journal of Nuclear Medicine | volume = 41 | issue = 4 | pages = 636–42 | date = April 2000 | pmid = 10768564 | doi =  }}
*{{cite journal | author=Jaïs P, Terris B, Ruszniewski P, ''et al.'' |title=Somatostatin receptor subtype gene expression in human endocrine gastroentero-pancreatic tumours. |journal=Eur. J. Clin. Invest. |volume=27 |issue= 8 |pages= 639-44 |year= 1997 |pmid= 9279525 |doi= }}
* {{cite journal | vauthors = Zatelli MC, Tagliati F, Taylor JE, Rossi R, Culler MD, degli Uberti EC | title = Somatostatin receptor subtypes 2 and 5 differentially affect proliferation in vitro of the human medullary thyroid carcinoma cell line tt | journal = The Journal of Clinical Endocrinology and Metabolism | volume = 86 | issue = 5 | pages = 2161–9 | date = May 2001 | pmid = 11344221 | doi = 10.1210/jc.86.5.2161 }}
*{{cite journal | author=Sharma K, Patel YC, Srikant CB |title=C-terminal region of human somatostatin receptor 5 is required for induction of Rb and G1 cell cycle arrest. |journal=Mol. Endocrinol. |volume=13 |issue= 1 |pages= 82-90 |year= 1999 |pmid= 9892014 |doi= }}
* {{cite journal | vauthors = Talme T, Ivanoff J, Hägglund M, Van Neerven RJ, Ivanoff A, Sundqvist KG | title = Somatostatin receptor (SSTR) expression and function in normal and leukaemic T-cells. Evidence for selective effects on adhesion to extracellular matrix components via SSTR2 and/or 3 | journal = Clinical and Experimental Immunology | volume = 125 | issue = 1 | pages = 71–9 | date = July 2001 | pmid = 11472428 | pmc = 1906108 | doi = 10.1046/j.1365-2249.2001.01577.x }}
*{{cite journal | author=Forssell-Aronsson EB, Nilsson O, Bejegård SA, ''et al.'' |title=111In-DTPA-D-Phe1-octreotide binding and somatostatin receptor subtypes in thyroid tumors. |journal=J. Nucl. Med. |volume=41 |issue= 4 |pages= 636-42 |year= 2000 |pmid= 10768564 |doi=  }}
* {{cite journal | vauthors = Pasquali D, Notaro A, Esposito D, Vassallo P, Bonavolontà G, Bellastella A, Sinisi AA | title = [Somatostatin receptor genes expression and effects of octreotide on orbital fibroblasts from Graves' ophthalmopathy] | journal = Minerva Endocrinologica | volume = 26 | issue = 3 | pages = 175–9 | date = September 2001 | pmid = 11753241 | doi =  }}
*{{cite journal | author=Zatelli MC, Tagliati F, Taylor JE, ''et al.'' |title=Somatostatin receptor subtypes 2 and 5 differentially affect proliferation in vitro of the human medullary thyroid carcinoma cell line tt. |journal=J. Clin. Endocrinol. Metab. |volume=86 |issue= 5 |pages= 2161-9 |year= 2001 |pmid= 11344221 |doi= }}
* {{cite journal | vauthors = Papotti M, Bongiovanni M, Volante M, Allìa E, Landolfi S, Helboe L, Schindler M, Cole SL, Bussolati G | title = Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis | journal = Virchows Archiv | volume = 440 | issue = 5 | pages = 461–75 | date = May 2002 | pmid = 12021920 | doi = 10.1007/s00428-002-0609-x }}
*{{cite journal | author=Talme T, Ivanoff J, Hägglund M, ''et al.'' |title=Somatostatin receptor (SSTR) expression and function in normal and leukaemic T-cells. Evidence for selective effects on adhesion to extracellular matrix components via SSTR2 and/or 3. |journal=Clin. Exp. Immunol. |volume=125 |issue= 1 |pages= 71-9 |year= 2001 |pmid= 11472428 |doi= }}
*{{cite journal | author=Pasquali D, Notaro A, Esposito D, ''et al.'' |title=[Somatostatin receptor genes expression and effects of octreotide on orbital fibroblasts from Graves' ophthalmopathy] |journal=Minerva Endocrinol. |volume=26 |issue= 3 |pages= 175-9 |year= 2002 |pmid= 11753241 |doi=  }}
*{{cite journal | author=Deloukas P, Matthews LH, Ashurst J, ''et al.'' |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865-71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a }}
*{{cite journal  | author=Papotti M, Bongiovanni M, Volante M, ''et al.'' |title=Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis. |journal=Virchows Arch. |volume=440 |issue= 5 |pages= 461-75 |year= 2002 |pmid= 12021920 |doi= 10.1007/s00428-002-0609-x }}
}}
{{refend}}
{{refend}}


==External links==
== External links ==
* [http://www.iuphar-db.org/GPCR/ChapterMenuForward?chapterID=1298 IUPHAR Receptor Database - Somatostatin Receptors]
* {{cite web | url = http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2441 | title = Somatostatin Receptors: sst<sub>4</sub> | accessdate = | format = | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | pages = | archiveurl = | archivedate = | quote = }}
* {{MeshName|somatostatin+receptor+subtype-4}}
* {{MeshName|somatostatin+receptor+subtype-4}}


{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
{{membrane-protein-stub}}
{{GH/IGF-1 axis signaling modulators}}
{{NLM content}}
{{NLM content}}
[[Category:G protein coupled receptors]]
 
{{WikiDoc Sources}}
[[Category:G protein-coupled receptors]]
{{transmembranereceptor-stub}}

Latest revision as of 07:15, 10 January 2019

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

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RefSeq (protein)

n/a

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Somatostatin receptor type 4 is a protein that in humans is encoded by the SSTR4 gene.[1][2]

Function

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung.[2]

See also

References

  1. ↑ Rohrer L, Raulf F, Bruns C, Buettner R, Hofstaedter F, Schüle R (May 1993). "Cloning and characterization of a fourth human somatostatin receptor". Proceedings of the National Academy of Sciences of the United States of America. 90 (9): 4196–200. doi:10.1073/pnas.90.9.4196. PMC 46473. PMID 8483934.
  2. ↑ 2.0 2.1 "Entrez Gene: SSTR4 somatostatin receptor 4".

Further reading

  • Patel YC (July 1999). "Somatostatin and its receptor family". Frontiers in Neuroendocrinology. 20 (3): 157–98. doi:10.1006/frne.1999.0183. PMID 10433861.
  • Yamada Y, Post SR, Wang K, Tager HS, Bell GI, Seino S (January 1992). "Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney". Proceedings of the National Academy of Sciences of the United States of America. 89 (1): 251–5. doi:10.1073/pnas.89.1.251. PMC 48214. PMID 1346068.
  • Demchyshyn LL, Srikant CB, Sunahara RK, Kent G, Seeman P, Van Tol HH, Panetta R, Patel YC, Niznik HB (June 1993). "Cloning and expression of a human somatostatin-14-selective receptor variant (somatostatin receptor 4) located on chromosome 20". Molecular Pharmacology. 43 (6): 894–901. PMID 8100352.
  • Yasuda K, Espinosa R, Davis EM, Le Beau MM, Bell GI (September 1993). "Human somatostatin receptor genes: localization of SSTR5 to human chromosome 20p11.2". Genomics. 17 (3): 785–6. doi:10.1006/geno.1993.1410. PMID 8244401.
  • Yamada Y, Kagimoto S, Kubota A, Yasuda K, Masuda K, Someya Y, Ihara Y, Li Q, Imura H, Seino S (September 1993). "Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype". Biochemical and Biophysical Research Communications. 195 (2): 844–52. doi:10.1006/bbrc.1993.2122. PMID 8373420.
  • Kaupmann K, Bruns C, Hoyer D, Seuwen K, Lübbert H (September 1993). "Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain". FEBS Letters. 331 (1–2): 53–9. doi:10.1016/0014-5793(93)80296-7. PMID 8405411.
  • Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI (February 1993). "Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms". Genomics. 15 (2): 449–52. doi:10.1006/geno.1993.1088. PMID 8449518.
  • Xu Y, Song J, Bruno JF, Berelowitz M (June 1993). "Molecular cloning and sequencing of a human somatostatin receptor, hSSTR4". Biochemical and Biophysical Research Communications. 193 (2): 648–52. doi:10.1006/bbrc.1993.1673. PMID 8512564.
  • Fukusumi S, Kitada C, Takekawa S, Kizawa H, Sakamoto J, Miyamoto M, Hinuma S, Kitano K, Fujino M (March 1997). "Identification and characterization of a novel human cortistatin-like peptide". Biochemical and Biophysical Research Communications. 232 (1): 157–63. doi:10.1006/bbrc.1997.6252. PMID 9125122.
  • de Lecea L, Ruiz-Lozano P, Danielson PE, Peelle-Kirley J, Foye PE, Frankel WN, Sutcliffe JG (June 1997). "Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin". Genomics. 42 (3): 499–506. doi:10.1006/geno.1997.4763. PMID 9205124.
  • Jaïs P, Terris B, Ruszniewski P, LeRomancer M, Reyl-Desmars F, Vissuzaine C, Cadiot G, Mignon M, Lewin MJ (August 1997). "Somatostatin receptor subtype gene expression in human endocrine gastroentero-pancreatic tumours". European Journal of Clinical Investigation. 27 (8): 639–44. doi:10.1046/j.1365-2362.1997.1740719.x. PMID 9279525.
  • Sharma K, Patel YC, Srikant CB (January 1999). "C-terminal region of human somatostatin receptor 5 is required for induction of Rb and G1 cell cycle arrest". Molecular Endocrinology. 13 (1): 82–90. doi:10.1210/me.13.1.82. PMID 9892014.
  • Forssell-Aronsson EB, Nilsson O, Bejegård SA, Kölby L, Bernhardt P, Mölne J, Hashemi SH, Wängberg B, Tisell LE, Ahlman H (April 2000). "111In-DTPA-D-Phe1-octreotide binding and somatostatin receptor subtypes in thyroid tumors". Journal of Nuclear Medicine. 41 (4): 636–42. PMID 10768564.
  • Zatelli MC, Tagliati F, Taylor JE, Rossi R, Culler MD, degli Uberti EC (May 2001). "Somatostatin receptor subtypes 2 and 5 differentially affect proliferation in vitro of the human medullary thyroid carcinoma cell line tt". The Journal of Clinical Endocrinology and Metabolism. 86 (5): 2161–9. doi:10.1210/jc.86.5.2161. PMID 11344221.
  • Talme T, Ivanoff J, Hägglund M, Van Neerven RJ, Ivanoff A, Sundqvist KG (July 2001). "Somatostatin receptor (SSTR) expression and function in normal and leukaemic T-cells. Evidence for selective effects on adhesion to extracellular matrix components via SSTR2 and/or 3". Clinical and Experimental Immunology. 125 (1): 71–9. doi:10.1046/j.1365-2249.2001.01577.x. PMC 1906108. PMID 11472428.
  • Pasquali D, Notaro A, Esposito D, Vassallo P, Bonavolontà G, Bellastella A, Sinisi AA (September 2001). "[Somatostatin receptor genes expression and effects of octreotide on orbital fibroblasts from Graves' ophthalmopathy]". Minerva Endocrinologica. 26 (3): 175–9. PMID 11753241.
  • Papotti M, Bongiovanni M, Volante M, Allìa E, Landolfi S, Helboe L, Schindler M, Cole SL, Bussolati G (May 2002). "Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis". Virchows Archiv. 440 (5): 461–75. doi:10.1007/s00428-002-0609-x. PMID 12021920.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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