Pancreatic polypeptide receptor 1: Difference between revisions

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Latest revision as of 18:01, 24 September 2018

Pancreatic polypeptide receptor 1, also known as Neuropeptide Y receptor type 4, is a protein that in humans is encoded by the PPYR1 gene.^[1]^[2]

Selective Ligands

Agonists

Pancreatic polypeptide
Neuropeptide Y (endogenous agonist, non subtype selective)
Peptide YY
GR-231,118 (mixed NPY₁ antagonist / NPY₄ agonist, CAS# 158859-98-4)

Antagonists

UR-AK49 ^[3]

References

↑ Lutz CM, Richards JE, Scott KL, Sinha S, Yang-Feng TL, Frankel WN, Thompson DA (Dec 1997). "Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not clustered with receptors specific for neuropeptide Y and peptide YY". Genomics. 46 (2): 287–90. doi:10.1006/geno.1997.5024. PMID 9417917.
↑ "Entrez Gene: PPYR1 pancreatic polypeptide receptor 1".
↑ Ziemek R, Schneider E, Kraus A, Cabrele C, Beck-Sickinger AG, Bernhardt G, Buschauer A (2007). "Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence". Journal of Receptor and Signal Transduction Research. 27 (4): 217–33. doi:10.1080/10799890701505206. PMID 17885919.

External links

"Neuropeptide Y Receptors: Y₄". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.

Keire DA, Bowers CW, Solomon TE, Reeve JR (Feb 2002). "Structure and receptor binding of PYY analogs". Peptides. 23 (2): 305–21. doi:10.1016/S0196-9781(01)00602-7. PMID 11825645.
Balasubramaniam A (Apr 2002). "Clinical potentials of neuropeptide Y family of hormones". American Journal of Surgery. 183 (4): 430–4. doi:10.1016/S0002-9610(02)00803-6. PMID 11975932.
Parker E, Van Heek M, Stamford A (Apr 2002). "Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status". European Journal of Pharmacology. 440 (2–3): 173–87. doi:10.1016/S0014-2999(02)01427-9. PMID 12007534.
Benaim G, Villalobo A (Aug 2002). "Phosphorylation of calmodulin. Functional implications". European Journal of Biochemistry / FEBS. 269 (15): 3619–31. doi:10.1046/j.1432-1033.2002.03038.x. PMID 12153558.
Lundell I, Blomqvist AG, Berglund MM, Schober DA, Johnson D, Statnick MA, Gadski RA, Gehlert DR, Larhammar D (Dec 1995). "Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY". The Journal of Biological Chemistry. 270 (49): 29123–8. doi:10.1074/jbc.270.49.29123. PMID 7493937.
Bard JA, Walker MW, Branchek TA, Weinshank RL (Nov 1995). "Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY". The Journal of Biological Chemistry. 270 (45): 26762–5. doi:10.1074/jbc.270.45.26762. PMID 7592911.
Yan H, Yang J, Marasco J, Yamaguchi K, Brenner S, Collins F, Karbon W (May 1996). "Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors". Proceedings of the National Academy of Sciences of the United States of America. 93 (10): 4661–5. doi:10.1073/pnas.93.10.4661. PMC 39335. PMID 8643460.
Kawabe T, Muslin AJ, Korsmeyer SJ (Jan 1997). "HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint". Nature. 385 (6615): 454–8. doi:10.1038/385454a0. PMID 9009195.
Darby K, Eyre HJ, Lapsys N, Copeland NG, Gilbert DJ, Couzens M, Antonova O, Sutherland GR, Jenkins NA, Herzog H (Dec 1997). "Assignment of the Y4 receptor gene (PPYR1) to human chromosome 10q11.2 and mouse chromosome 14". Genomics. 46 (3): 513–5. doi:10.1006/geno.1997.5071. PMID 9441761.
Hsieh-Wilson LC, Allen PB, Watanabe T, Nairn AC, Greengard P (Apr 1999). "Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1". Biochemistry. 38 (14): 4365–73. doi:10.1021/bi982900m. PMID 10194355.
Smith FD, Oxford GS, Milgram SL (Jul 1999). "Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein". The Journal of Biological Chemistry. 274 (28): 19894–900. doi:10.1074/jbc.274.28.19894. PMID 10391935.
Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR (May 2000). "PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts". Cell. 101 (4): 365–76. doi:10.1016/S0092-8674(00)80847-8. PMID 10830164.
Connor JH, Weiser DC, Li S, Hallenbeck JM, Shenolikar S (Oct 2001). "Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1". Molecular and Cellular Biology. 21 (20): 6841–50. doi:10.1128/MCB.21.20.6841-6850.2001. PMC 99861. PMID 11564868.
Cavadas C, Silva AP, Mosimann F, Cotrim MD, Ribeiro CA, Brunner HR, Grouzmann E (Dec 2001). "NPY regulates catecholamine secretion from human adrenal chromaffin cells". The Journal of Clinical Endocrinology and Metabolism. 86 (12): 5956–63. doi:10.1210/jc.86.12.5956. PMID 11739470.
Cox HM, Tough IR (Mar 2002). "Neuropeptide Y, Y1, Y2 and Y4 receptors mediate Y agonist responses in isolated human colon mucosa". British Journal of Pharmacology. 135 (6): 1505–12. doi:10.1038/sj.bjp.0704604. PMC 1573267. PMID 11906964.
Wu DY, Tkachuck DC, Roberson RS, Schubach WH (Aug 2002). "The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity". The Journal of Biological Chemistry. 277 (31): 27706–15. doi:10.1074/jbc.M200955200. PMID 12016208.

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[pmid9417917-1] Lutz CM, Richards JE, Scott KL, Sinha S, Yang-Feng TL, Frankel WN, Thompson DA (Dec 1997). "Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not clustered with receptors specific for neuropeptide Y and peptide YY". Genomics. 46 (2): 287–90. doi:10.1006/geno.1997.5024. PMID 9417917.

[entrez-2] "Entrez Gene: PPYR1 pancreatic polypeptide receptor 1".

[pmid17885919-3] Ziemek R, Schneider E, Kraus A, Cabrele C, Beck-Sickinger AG, Bernhardt G, Buschauer A (2007). "Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence". Journal of Receptor and Signal Transduction Research. 27 (4): 217–33. doi:10.1080/10799890701505206. PMID 17885919.

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Pancreatic polypeptide receptor 1''', also known as '''Neuropeptide Y receptor type 4''', is a [[protein]] that in humans is encoded by the ''PPYR1'' [[gene]].<ref name="pmid9417917">{{cite journal | vauthors = Lutz CM, Richards JE, Scott KL, Sinha S, Yang-Feng TL, Frankel WN, Thompson DA | title = Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not clustered with receptors specific for neuropeptide Y and peptide YY | journal = Genomics | volume = 46 | issue = 2 | pages = 287–90 | date = Dec 1997 | pmid = 9417917 | pmc =  | doi = 10.1006/geno.1997.5024 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PPYR1 pancreatic polypeptide receptor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5540| accessdate = }}</ref>
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-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Pancreatic polypeptide receptor 1
- | HGNCid = 9329
- | Symbol = PPYR1
- | AltSymbols =; PP1; MGC116897; NPY4-R; NPY4R; Y4
- | OMIM = 601790
- | ECnumber =
- | Homologene = 38119
- | MGIid = 105374
- | GeneAtlas_image1 = PBB_GE_PPYR1_210956_at_tn.png
- | Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0001601 |text = peptide YY receptor activity}} {{GNF_GO|id=GO:0001602 |text = pancreatic polypeptide receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}}
- | Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
- | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007586 |text = digestion}} {{GNF_GO|id=GO:0007631 |text = feeding behavior}} {{GNF_GO|id=GO:0008015 |text = circulation}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 5540
-    | Hs_Ensembl = ENSG00000204174
-    | Hs_RefseqProtein = XP_001129329
-    | Hs_RefseqmRNA = XM_001129329
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 10
-    | Hs_GenLoc_start = 46503540
-    | Hs_GenLoc_end = 46508326
-    | Hs_Uniprot = P50391
-    | Mm_EntrezGene = 19065
-    | Mm_Ensembl = ENSMUSG00000048337
-    | Mm_RefseqmRNA = NM_008919
-    | Mm_RefseqProtein = NP_032945
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 14
-    | Mm_GenLoc_start = 32973084
-    | Mm_GenLoc_end = 32981581
-    | Mm_Uniprot = Q3UN46
-  }}
-}}
-'''Pancreatic polypeptide receptor 1''', also known as '''PPYR1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PPYR1 pancreatic polypeptide receptor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5540| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+==Selective Ligands==
-{{PBB_Summary
+===Agonists===
-| section_title =
+* [[Pancreatic polypeptide]]
-| summary_text =
+* [[Neuropeptide Y]] (endogenous agonist, non subtype selective)
-}}
+* [[Peptide YY]]
+* GR-231,118 (mixed NPY<sub>1</sub> antagonist / NPY<sub>4</sub> agonist, CAS# 158859-98-4)
-==See also==
+===Antagonists===
+* [[UR-AK49]] <ref name="pmid17885919">{{cite journal | vauthors = Ziemek R, Schneider E, Kraus A, Cabrele C, Beck-Sickinger AG, Bernhardt G, Buschauer A | title = Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence | journal = Journal of Receptor and Signal Transduction Research | volume = 27 | issue = 4 | pages = 217–33 | year = 2007 | pmid = 17885919 | doi = 10.1080/10799890701505206 }}</ref>
+== See also ==
 * [[Neuropeptide Y receptor]]
-==References==
+== References ==
-{{reflist|2}}
+{{reflist}}
-==Further reading==
+== External links ==
-{{refbegin | 2}}
+* {{cite web | url = http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2370 | title = Neuropeptide Y Receptors: Y<sub>4</sub> | accessdate = | authorlink = | date = | format = | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | pages = | archiveurl = | archivedate = | quote = }}
-{{PBB_Further_reading
-| citations =
+== Further reading ==
-*{{cite journal  | author=Keire DA, Bowers CW, Solomon TE, Reeve JR |title=Structure and receptor binding of PYY analogs. |journal=Peptides |volume=23 |issue= 2 |pages= 305-21 |year= 2002 |pmid= 11825645 |doi=  }}
+{{refbegin |33em}}
-*{{cite journal  | author=Balasubramaniam A |title=Clinical potentials of neuropeptide Y family of hormones. |journal=Am. J. Surg. |volume=183 |issue= 4 |pages= 430-4 |year= 2002 |pmid= 11975932 |doi=  }}
+* {{cite journal | vauthors = Keire DA, Bowers CW, Solomon TE, Reeve JR | title = Structure and receptor binding of PYY analogs | journal = Peptides | volume = 23 | issue = 2 | pages = 305–21 | date = Feb 2002 | pmid = 11825645 | doi = 10.1016/S0196-9781(01)00602-7 }}
-*{{cite journal  | author=Parker E, Van Heek M, Stamford A |title=Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status. |journal=Eur. J. Pharmacol. |volume=440 |issue= 2-3 |pages= 173-87 |year= 2002 |pmid= 12007534 |doi=  }}
+* {{cite journal | vauthors = Balasubramaniam A | title = Clinical potentials of neuropeptide Y family of hormones | journal = American Journal of Surgery | volume = 183 | issue = 4 | pages = 430–4 | date = Apr 2002 | pmid = 11975932 | doi = 10.1016/S0002-9610(02)00803-6 }}
-*{{cite journal  | author=Benaim G, Villalobo A |title=Phosphorylation of calmodulin. Functional implications. |journal=Eur. J. Biochem. |volume=269 |issue= 15 |pages= 3619-31 |year= 2002 |pmid= 12153558 |doi=  }}
+* {{cite journal | vauthors = Parker E, Van Heek M, Stamford A | title = Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status | journal = European Journal of Pharmacology | volume = 440 | issue = 2-3 | pages = 173–87 | date = Apr 2002 | pmid = 12007534 | doi = 10.1016/S0014-2999(02)01427-9 }}
-*{{cite journal  | author=Lundell I, Blomqvist AG, Berglund MM, ''et al.'' |title=Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY. |journal=J. Biol. Chem. |volume=270 |issue= 49 |pages= 29123-8 |year= 1996 |pmid= 7493937 |doi=  }}
+* {{cite journal | vauthors = Benaim G, Villalobo A | title = Phosphorylation of calmodulin. Functional implications | journal = European Journal of Biochemistry / FEBS | volume = 269 | issue = 15 | pages = 3619–31 | date = Aug 2002 | pmid = 12153558 | doi = 10.1046/j.1432-1033.2002.03038.x }}
-*{{cite journal  | author=Bard JA, Walker MW, Branchek TA, Weinshank RL |title=Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY. |journal=J. Biol. Chem. |volume=270 |issue= 45 |pages= 26762-5 |year= 1995 |pmid= 7592911 |doi=  }}
+* {{cite journal | vauthors = Lundell I, Blomqvist AG, Berglund MM, Schober DA, Johnson D, Statnick MA, Gadski RA, Gehlert DR, Larhammar D | title = Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY | journal = The Journal of Biological Chemistry | volume = 270 | issue = 49 | pages = 29123–8 | date = Dec 1995 | pmid = 7493937 | doi = 10.1074/jbc.270.49.29123 }}
-*{{cite journal  | author=Yan H, Yang J, Marasco J, ''et al.'' |title=Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 10 |pages= 4661-5 |year= 1996 |pmid= 8643460 |doi=  }}
+* {{cite journal | vauthors = Bard JA, Walker MW, Branchek TA, Weinshank RL | title = Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY | journal = The Journal of Biological Chemistry | volume = 270 | issue = 45 | pages = 26762–5 | date = Nov 1995 | pmid = 7592911 | doi = 10.1074/jbc.270.45.26762 }}
-*{{cite journal  | author=Kawabe T, Muslin AJ, Korsmeyer SJ |title=HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint. |journal=Nature |volume=385 |issue= 6615 |pages= 454-8 |year= 1997 |pmid= 9009195 |doi= 10.1038/385454a0 }}
+* {{cite journal | vauthors = Yan H, Yang J, Marasco J, Yamaguchi K, Brenner S, Collins F, Karbon W | title = Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 93 | issue = 10 | pages = 4661–5 | date = May 1996 | pmid = 8643460 | pmc = 39335 | doi = 10.1073/pnas.93.10.4661 }}
-*{{cite journal  | author=Lutz CM, Richards JE, Scott KL, ''et al.'' |title=Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not clustered with receptors specific for neuropeptide Y and peptide YY. |journal=Genomics |volume=46 |issue= 2 |pages= 287-90 |year= 1998 |pmid= 9417917 |doi= 10.1006/geno.1997.5024 }}
+* {{cite journal | vauthors = Kawabe T, Muslin AJ, Korsmeyer SJ | title = HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint | journal = Nature | volume = 385 | issue = 6615 | pages = 454–8 | date = Jan 1997 | pmid = 9009195 | doi = 10.1038/385454a0 }}
-*{{cite journal  | author=Darby K, Eyre HJ, Lapsys N, ''et al.'' |title=Assignment of the Y4 receptor gene (PPYR1) to human chromosome 10q11.2 and mouse chromosome 14. |journal=Genomics |volume=46 |issue= 3 |pages= 513-5 |year= 1998 |pmid= 9441761 |doi= 10.1006/geno.1997.5071 }}
+* {{cite journal | vauthors = Darby K, Eyre HJ, Lapsys N, Copeland NG, Gilbert DJ, Couzens M, Antonova O, Sutherland GR, Jenkins NA, Herzog H | title = Assignment of the Y4 receptor gene (PPYR1) to human chromosome 10q11.2 and mouse chromosome 14 | journal = Genomics | volume = 46 | issue = 3 | pages = 513–5 | date = Dec 1997 | pmid = 9441761 | doi = 10.1006/geno.1997.5071 }}
-*{{cite journal  | author=Hsieh-Wilson LC, Allen PB, Watanabe T, ''et al.'' |title=Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1. |journal=Biochemistry |volume=38 |issue= 14 |pages= 4365-73 |year= 1999 |pmid= 10194355 |doi= 10.1021/bi982900m }}
+* {{cite journal | vauthors = Hsieh-Wilson LC, Allen PB, Watanabe T, Nairn AC, Greengard P | title = Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1 | journal = Biochemistry | volume = 38 | issue = 14 | pages = 4365–73 | date = Apr 1999 | pmid = 10194355 | doi = 10.1021/bi982900m }}
-*{{cite journal  | author=Smith FD, Oxford GS, Milgram SL |title=Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein. |journal=J. Biol. Chem. |volume=274 |issue= 28 |pages= 19894-900 |year= 1999 |pmid= 10391935 |doi=  }}
+* {{cite journal | vauthors = Smith FD, Oxford GS, Milgram SL | title = Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein | journal = The Journal of Biological Chemistry | volume = 274 | issue = 28 | pages = 19894–900 | date = Jul 1999 | pmid = 10391935 | doi = 10.1074/jbc.274.28.19894 }}
-*{{cite journal  | author=Marx SO, Reiken S, Hisamatsu Y, ''et al.'' |title=PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. |journal=Cell |volume=101 |issue= 4 |pages= 365-76 |year= 2000 |pmid= 10830164 |doi=  }}
+* {{cite journal | vauthors = Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR | title = PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts | journal = Cell | volume = 101 | issue = 4 | pages = 365–76 | date = May 2000 | pmid = 10830164 | doi = 10.1016/S0092-8674(00)80847-8 }}
-*{{cite journal  | author=Connor JH, Weiser DC, Li S, ''et al.'' |title=Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1. |journal=Mol. Cell. Biol. |volume=21 |issue= 20 |pages= 6841-50 |year= 2001 |pmid= 11564868 |doi= 10.1128/MCB.21.20.6841-6850.2001 }}
+* {{cite journal | vauthors = Connor JH, Weiser DC, Li S, Hallenbeck JM, Shenolikar S | title = Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1 | journal = Molecular and Cellular Biology | volume = 21 | issue = 20 | pages = 6841–50 | date = Oct 2001 | pmid = 11564868 | pmc = 99861 | doi = 10.1128/MCB.21.20.6841-6850.2001 }}
-*{{cite journal  | author=Cavadas C, Silva AP, Mosimann F, ''et al.'' |title=NPY regulates catecholamine secretion from human adrenal chromaffin cells. |journal=J. Clin. Endocrinol. Metab. |volume=86 |issue= 12 |pages= 5956-63 |year= 2001 |pmid= 11739470 |doi=  }}
+* {{cite journal | vauthors = Cavadas C, Silva AP, Mosimann F, Cotrim MD, Ribeiro CA, Brunner HR, Grouzmann E | title = NPY regulates catecholamine secretion from human adrenal chromaffin cells | journal = The Journal of Clinical Endocrinology and Metabolism | volume = 86 | issue = 12 | pages = 5956–63 | date = Dec 2001 | pmid = 11739470 | doi = 10.1210/jc.86.12.5956 }}
-*{{cite journal  | author=Cox HM, Tough IR |title=Neuropeptide Y, Y1, Y2 and Y4 receptors mediate Y agonist responses in isolated human colon mucosa. |journal=Br. J. Pharmacol. |volume=135 |issue= 6 |pages= 1505-12 |year= 2002 |pmid= 11906964 |doi= 10.1038/sj.bjp.0704604 }}
+* {{cite journal | vauthors = Cox HM, Tough IR | title = Neuropeptide Y, Y1, Y2 and Y4 receptors mediate Y agonist responses in isolated human colon mucosa | journal = British Journal of Pharmacology | volume = 135 | issue = 6 | pages = 1505–12 | date = Mar 2002 | pmid = 11906964 | pmc = 1573267 | doi = 10.1038/sj.bjp.0704604 }}
-*{{cite journal  | author=Wu DY, Tkachuck DC, Roberson RS, Schubach WH |title=The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity. |journal=J. Biol. Chem. |volume=277 |issue= 31 |pages= 27706-15 |year= 2002 |pmid= 12016208 |doi= 10.1074/jbc.M200955200 }}
+* {{cite journal | vauthors = Wu DY, Tkachuck DC, Roberson RS, Schubach WH | title = The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity | journal = The Journal of Biological Chemistry | volume = 277 | issue = 31 | pages = 27706–15 | date = Aug 2002 | pmid = 12016208 | doi = 10.1074/jbc.M200955200 }}
-}}
 {{refend}}
-{{membrane-protein-stub}}
+{{transmembranereceptor-stub}}
 {{NLM content}}
-{{G protein-coupled receptors}}
+{{G protein-coupled receptors|g1}}
-[[Category:G protein coupled receptors]]
+{{Neuropeptidergics}}
-{{WikiDoc Sources}}
+[[Category:G protein-coupled receptors]]

Pancreatic polypeptide receptor 1: Difference between revisions

Latest revision as of 18:01, 24 September 2018

Contents

Selective Ligands

Agonists

Antagonists

See also

References

External links

Further reading

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