Relaxin/insulin-like family peptide receptor 3: Difference between revisions

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imported>Ser Amantio di Nicolao
 
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{{Infobox_gene}}
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'''Relaxin/insulin-like family peptide receptor 3''', also known as '''RXFP3''', is a human [[G-protein coupled receptor]].<ref name="entrez">{{cite web | title = Entrez Gene: RXFP3 relaxin/insulin-like family peptide receptor 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51289| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Relaxin/insulin-like family peptide receptor 3
| HGNCid = 24883
| Symbol = RXFP3
| AltSymbols =; GPCR135; MGC141998; MGC142000; RLN3R1; SALPR
| OMIM = 609445
| ECnumber = 
| Homologene = 9568
| MGIid = 2441827
| GeneAtlas_image1 = PBB_GE_RXFP3_221066_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004982 |text = N-formyl peptide receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0051482 |text = elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 51289
    | Hs_Ensembl = ENSG00000182631
    | Hs_RefseqProtein = NP_057652
    | Hs_RefseqmRNA = NM_016568
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 5
    | Hs_GenLoc_start = 33972246
    | Hs_GenLoc_end = 33974099
    | Hs_Uniprot = Q9NSD7
    | Mm_EntrezGene = 239336
    | Mm_Ensembl = ENSMUSG00000060735
    | Mm_RefseqmRNA = NM_178717
    | Mm_RefseqProtein = NP_848832
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 15
    | Mm_GenLoc_start = 10980591
    | Mm_GenLoc_end = 10982009
    | Mm_Uniprot = Q5Y988
  }}
}}
'''Relaxin/insulin-like family peptide receptor 3''', also known as '''RXFP3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RXFP3 relaxin/insulin-like family peptide receptor 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51289| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==External links==
*{{cite web | url = http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=3024 | title = Relaxin Family Peptide Receptors: RXFP3 | accessdate = | date = | format = | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | pages = | language = | archiveurl = | archivedate = | quote = }}


==Further reading==
==Further reading==
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{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Bathgate RA, Ivell R, Sanborn BM, ''et al.'' |title=Receptors for relaxin family peptides. |journal=Ann. N. Y. Acad. Sci. |volume=1041 |issue=  |pages= 61-76 |year= 2005 |pmid= 15956688 |doi= 10.1196/annals.1282.010 }}
*{{cite journal   |vauthors=Bathgate RA, Ivell R, Sanborn BM, etal |title=Receptors for relaxin family peptides. |journal=Ann. N. Y. Acad. Sci. |volume=1041 |issue=  |pages= 61–76 |year= 2005 |pmid= 15956688 |doi= 10.1196/annals.1282.010 }}
*{{cite journal | author=Bathgate RA, Ivell R, Sanborn BM, ''et al.'' |title=International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides. |journal=Pharmacol. Rev. |volume=58 |issue= 1 |pages= 7-31 |year= 2006 |pmid= 16507880 |doi= 10.1124/pr.58.1.9 }}
*{{cite journal   |vauthors=Bathgate RA, Ivell R, Sanborn BM, etal |title=International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides. |journal=Pharmacol. Rev. |volume=58 |issue= 1 |pages= 7–31 |year= 2006 |pmid= 16507880 |doi= 10.1124/pr.58.1.9 }}
*{{cite journal | author=Matsumoto M, Kamohara M, Sugimoto T, ''et al.'' |title=The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors. |journal=Gene |volume=248 |issue= 1-2 |pages= 183-9 |year= 2000 |pmid= 10806363 |doi=  }}
*{{cite journal   |vauthors=Matsumoto M, Kamohara M, Sugimoto T, etal |title=The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors. |journal=Gene |volume=248 |issue= 1–2 |pages= 183–9 |year= 2000 |pmid= 10806363 |doi=10.1016/S0378-1119(00)00123-2 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Liu C, Eriste E, Sutton S, ''et al.'' |title=Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135. |journal=J. Biol. Chem. |volume=278 |issue= 50 |pages= 50754-64 |year= 2004 |pmid= 14522968 |doi= 10.1074/jbc.M308995200 }}
*{{cite journal   |vauthors=Liu C, Eriste E, Sutton S, etal |title=Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135 |journal=J. Biol. Chem. |volume=278 |issue= 50 |pages= 50754–64 |year= 2004 |pmid= 14522968 |doi= 10.1074/jbc.M308995200 }}
*{{cite journal | author=Liu C, Chen J, Kuei C, ''et al.'' |title=Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7. |journal=Mol. Pharmacol. |volume=67 |issue= 1 |pages= 231-40 |year= 2005 |pmid= 15465925 |doi= 10.1124/mol.104.006700 }}
*{{cite journal   |vauthors=Liu C, Chen J, Kuei C, etal |title=Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7 |journal=Mol. Pharmacol. |volume=67 |issue= 1 |pages= 231–40 |year= 2005 |pmid= 15465925 |doi= 10.1124/mol.104.006700 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal  | author=Van der Westhuizen ET, Sexton PM, Bathgate RA, Summers RJ |title=Responses of GPCR135 to human gene 3 (H3) relaxin in CHO-K1 cells determined by microphysiometry. |journal=Ann. N. Y. Acad. Sci. |volume=1041 |issue=  |pages= 332-7 |year= 2005 |pmid= 15956730 |doi= 10.1196/annals.1282.053 }}
*{{cite journal  |vauthors=Van der Westhuizen ET, Sexton PM, Bathgate RA, Summers RJ |title=Responses of GPCR135 to human gene 3 (H3) relaxin in CHO-K1 cells determined by microphysiometry |journal=Ann. N. Y. Acad. Sci. |volume=1041 |issue=  |pages= 332–7 |year= 2005 |pmid= 15956730 |doi= 10.1196/annals.1282.053 }}
}}
}}
{{refend}}
{{refend}}
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{{NLM content}}
{{NLM content}}
{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
[[Category:G protein coupled receptors]]
{{Protein and peptide receptor modulators}}
 
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{{WH}}
{{DEFAULTSORT:Relaxin insulin-like family peptide receptor 3}}
{{WS}}
[[Category:G protein-coupled receptors]]
{{transmembranereceptor-stub}}

Latest revision as of 18:01, 24 September 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Relaxin/insulin-like family peptide receptor 3, also known as RXFP3, is a human G-protein coupled receptor.[1]


See also

References

  1. ↑ "Entrez Gene: RXFP3 relaxin/insulin-like family peptide receptor 3".

External links

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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