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{{Infobox_gene}}
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'''Somatostatin receptor type 5''' is a [[protein]] that in humans is encoded by the ''SSTR5'' [[gene]].<ref name="pmid7607700">{{cite journal |vauthors=Takeda J, Fernald AA, Yamagata K, Le Beau MM, Bell GI | title = Localization of human somatostatin receptor 5 gene (SSTR5) to chromosome band 16p13.3 by fluorescence in situ hybridization | journal = Genomics | volume = 26 | issue = 3 | pages = 638–9 |date=Aug 1995 | pmid = 7607700 | pmc =  | doi =10.1016/0888-7543(95)80195-R }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Somatostatin receptor 5
| HGNCid = 11334
| Symbol = SSTR5
| AltSymbols =;
| OMIM = 182455
| ECnumber =
| Homologene = 20287
| MGIid = 894282
  | GeneAtlas_image1 = PBB_GE_SSTR5_214555_at_tn.png
| Function = {{GNF_GO|id=GO:0001584 |text = rhodopsin-like receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004994 |text = somatostatin receptor activity}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007187 |text = G-protein signaling, coupled to cyclic nucleotide second messenger}} {{GNF_GO|id=GO:0008285 |text = negative regulation of cell proliferation}} {{GNF_GO|id=GO:0042593 |text = glucose homeostasis}} {{GNF_GO|id=GO:0050796 |text = regulation of insulin secretion}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6755
    | Hs_Ensembl = ENSG00000162009
    | Hs_RefseqProtein = NP_001044
    | Hs_RefseqmRNA = NM_001053
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 16
    | Hs_GenLoc_start = 1068870
    | Hs_GenLoc_end = 1069964
    | Hs_Uniprot = P35346
    | Mm_EntrezGene = 20609
    | Mm_Ensembl = ENSMUSG00000050824
    | Mm_RefseqmRNA = NM_011425
    | Mm_RefseqProtein = NP_035555
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 17
    | Mm_GenLoc_start = 25217475
    | Mm_GenLoc_end = 25224853
    | Mm_Uniprot = O35715
  }}
}}
'''Somatostatin receptor 5''', also known as '''SSTR5''', is a human [[gene]].


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| section_title =  
| section_title =  
| summary_text = Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins.  The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner.  SSTR5 is a member of the superfamily of receptors having seven transmembrane segments.<ref name="entrez">{{cite web | title = Entrez Gene: SSTR5 somatostatin receptor 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6755| accessdate = }}</ref>
| summary_text = Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins.  The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner.  SSTR5 is a member of the superfamily of receptors having seven transmembrane segments.<ref name="entrez">{{cite web | title = Entrez Gene: SSTR5 somatostatin receptor 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6755| accessdate = }}</ref>
}}
}}


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==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
Line 64: Line 18:
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Yamada Y, Post SR, Wang K, ''et al.'' |title=Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 1 |pages= 251-5 |year= 1992 |pmid= 1346068 |doi=  }}
*{{cite journal   |vauthors=Yamada Y, Post SR, Wang K, etal |title=Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 1 |pages= 251–5 |year= 1992 |pmid= 1346068 |doi=10.1073/pnas.89.1.251  | pmc=48214 }}
*{{cite journal  | author=Montminy MR, Goodman RH, Horovitch SJ, Habener JF |title=Primary structure of the gene encoding rat preprosomatostatin. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=81 |issue= 11 |pages= 3337-40 |year= 1984 |pmid= 6145156 |doi= }}
*{{cite journal  |vauthors=Montminy MR, Goodman RH, Horovitch SJ, Habener JF |title=Primary structure of the gene encoding rat preprosomatostatin. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=81 |issue= 11 |pages= 3337–40 |year= 1984 |pmid= 6145156 |doi=10.1073/pnas.81.11.3337  | pmc=345502  }}
*{{cite journal | author=Takeda J, Fernald AA, Yamagata K, ''et al.'' |title=Localization of human somatostatin receptor 5 gene (SSTR5) to chromosome band 16p13.3 by fluorescence in situ hybridization. |journal=Genomics |volume=26 |issue= 3 |pages= 638-9 |year= 1995 |pmid= 7607700 |doi=  }}
*{{cite journal   |vauthors=Panetta R, Greenwood MT, Warszynska A, etal |title=Molecular cloning, functional characterization, and chromosomal localization of a human somatostatin receptor (somatostatin receptor type 5) with preferential affinity for somatostatin-28. |journal=Mol. Pharmacol. |volume=45 |issue= 3 |pages= 417–27 |year= 1994 |pmid= 7908405 |doi=  }}
*{{cite journal  | author=Panetta R, Greenwood MT, Warszynska A, ''et al.'' |title=Molecular cloning, functional characterization, and chromosomal localization of a human somatostatin receptor (somatostatin receptor type 5) with preferential affinity for somatostatin-28. |journal=Mol. Pharmacol. |volume=45 |issue= 3 |pages= 417-27 |year= 1994 |pmid= 7908405 |doi=  }}
*{{cite journal  |vauthors=O'Carroll AM, Raynor K, Lolait SJ, Reisine T |title=Characterization of cloned human somatostatin receptor SSTR5. |journal=Mol. Pharmacol. |volume=46 |issue= 2 |pages= 291–8 |year= 1994 |pmid= 8078491 |doi=  }}
*{{cite journal | author=O'Carroll AM, Raynor K, Lolait SJ, Reisine T |title=Characterization of cloned human somatostatin receptor SSTR5. |journal=Mol. Pharmacol. |volume=46 |issue= 2 |pages= 291-8 |year= 1994 |pmid= 8078491 |doi=  }}
*{{cite journal   |vauthors=Yamada Y, Kagimoto S, Kubota A, etal |title=Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype. |journal=Biochem. Biophys. Res. Commun. |volume=195 |issue= 2 |pages= 844–52 |year= 1993 |pmid= 8373420 |doi=10.1006/bbrc.1993.2122 }}
*{{cite journal | author=Yamada Y, Kagimoto S, Kubota A, ''et al.'' |title=Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype. |journal=Biochem. Biophys. Res. Commun. |volume=195 |issue= 2 |pages= 844-52 |year= 1993 |pmid= 8373420 |doi= }}
*{{cite journal   |vauthors=Yamada Y, Stoffel M, Espinosa R, etal |title=Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms. |journal=Genomics |volume=15 |issue= 2 |pages= 449–52 |year= 1993 |pmid= 8449518 |doi= 10.1006/geno.1993.1088 }}
*{{cite journal | author=Yamada Y, Stoffel M, Espinosa R, ''et al.'' |title=Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms. |journal=Genomics |volume=15 |issue= 2 |pages= 449-52 |year= 1993 |pmid= 8449518 |doi= 10.1006/geno.1993.1088 }}
*{{cite journal   |vauthors=Fukusumi S, Kitada C, Takekawa S, etal |title=Identification and characterization of a novel human cortistatin-like peptide. |journal=Biochem. Biophys. Res. Commun. |volume=232 |issue= 1 |pages= 157–63 |year= 1997 |pmid= 9125122 |doi= 10.1006/bbrc.1997.6252 }}
*{{cite journal  | author=Fukusumi S, Kitada C, Takekawa S, ''et al.'' |title=Identification and characterization of a novel human cortistatin-like peptide. |journal=Biochem. Biophys. Res. Commun. |volume=232 |issue= 1 |pages= 157-63 |year= 1997 |pmid= 9125122 |doi= 10.1006/bbrc.1997.6252 }}
*{{cite journal  |vauthors=Ain KB, Taylor KD, Tofiq S, Venkataraman G |title=Somatostatin receptor subtype expression in human thyroid and thyroid carcinoma cell lines. |journal=J. Clin. Endocrinol. Metab. |volume=82 |issue= 6 |pages= 1857–62 |year= 1997 |pmid= 9177396 |doi=10.1210/jc.82.6.1857  }}
*{{cite journal | author=Ain KB, Taylor KD, Tofiq S, Venkataraman G |title=Somatostatin receptor subtype expression in human thyroid and thyroid carcinoma cell lines. |journal=J. Clin. Endocrinol. Metab. |volume=82 |issue= 6 |pages= 1857-62 |year= 1997 |pmid= 9177396 |doi= }}
*{{cite journal   |vauthors=de Lecea L, Ruiz-Lozano P, Danielson PE, etal |title=Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin. |journal=Genomics |volume=42 |issue= 3 |pages= 499–506 |year= 1997 |pmid= 9205124 |doi= 10.1006/geno.1997.4763 }}
*{{cite journal | author=de Lecea L, Ruiz-Lozano P, Danielson PE, ''et al.'' |title=Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin. |journal=Genomics |volume=42 |issue= 3 |pages= 499-506 |year= 1997 |pmid= 9205124 |doi= 10.1006/geno.1997.4763 }}
*{{cite journal   |vauthors=Jaïs P, Terris B, Ruszniewski P, etal |title=Somatostatin receptor subtype gene expression in human endocrine gastroentero-pancreatic tumours. |journal=Eur. J. Clin. Invest. |volume=27 |issue= 8 |pages= 639–44 |year= 1997 |pmid= 9279525 |doi=10.1046/j.1365-2362.1997.1740719.x  }}
*{{cite journal | author=Jaïs P, Terris B, Ruszniewski P, ''et al.'' |title=Somatostatin receptor subtype gene expression in human endocrine gastroentero-pancreatic tumours. |journal=Eur. J. Clin. Invest. |volume=27 |issue= 8 |pages= 639-44 |year= 1997 |pmid= 9279525 |doi= }}
*{{cite journal   |vauthors=Hukovic N, Panetta R, Kumar U, etal |title=The cytoplasmic tail of the human somatostatin receptor type 5 is crucial for interaction with adenylyl cyclase and in mediating desensitization and internalization. |journal=J. Biol. Chem. |volume=273 |issue= 33 |pages= 21416–22 |year= 1998 |pmid= 9694905 |doi=10.1074/jbc.273.33.21416  }}
*{{cite journal  | author=Hukovic N, Panetta R, Kumar U, ''et al.'' |title=The cytoplasmic tail of the human somatostatin receptor type 5 is crucial for interaction with adenylyl cyclase and in mediating desensitization and internalization. |journal=J. Biol. Chem. |volume=273 |issue= 33 |pages= 21416-22 |year= 1998 |pmid= 9694905 |doi=  }}
*{{cite journal  |vauthors=Sharma K, Patel YC, Srikant CB |title=C-terminal region of human somatostatin receptor 5 is required for induction of Rb and G1 cell cycle arrest. |journal=Mol. Endocrinol. |volume=13 |issue= 1 |pages= 82–90 |year= 1999 |pmid= 9892014 |doi=10.1210/me.13.1.82 }}
*{{cite journal | author=Sharma K, Patel YC, Srikant CB |title=C-terminal region of human somatostatin receptor 5 is required for induction of Rb and G1 cell cycle arrest. |journal=Mol. Endocrinol. |volume=13 |issue= 1 |pages= 82-90 |year= 1999 |pmid= 9892014 |doi=  }}
*{{cite journal   |vauthors=Kumar U, Sasi R, Suresh S, etal |title=Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis. |journal=Diabetes |volume=48 |issue= 1 |pages= 77–85 |year= 1999 |pmid= 9892225 |doi=10.2337/diabetes.48.1.77 }}
*{{cite journal | author=Kumar U, Sasi R, Suresh S, ''et al.'' |title=Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis. |journal=Diabetes |volume=48 |issue= 1 |pages= 77-85 |year= 1999 |pmid= 9892225 |doi=  }}
*{{cite journal   |vauthors=Rocheville M, Lange DC, Kumar U, etal |title=Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers. |journal=J. Biol. Chem. |volume=275 |issue= 11 |pages= 7862–9 |year= 2000 |pmid= 10713101 |doi=10.1074/jbc.275.11.7862 }}
*{{cite journal | author=Rocheville M, Lange DC, Kumar U, ''et al.'' |title=Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers. |journal=J. Biol. Chem. |volume=275 |issue= 11 |pages= 7862-9 |year= 2000 |pmid= 10713101 |doi=  }}
*{{cite journal   |vauthors=Rocheville M, Lange DC, Kumar U, etal |title=Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity. |journal=Science |volume=288 |issue= 5463 |pages= 154–7 |year= 2000 |pmid= 10753124 |doi=10.1126/science.288.5463.154 }}
*{{cite journal | author=Rocheville M, Lange DC, Kumar U, ''et al.'' |title=Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity. |journal=Science |volume=288 |issue= 5463 |pages= 154-7 |year= 2000 |pmid= 10753124 |doi=  }}
*{{cite journal   |vauthors=Daniels RJ, Peden JF, Lloyd C, etal |title=Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. |journal=Hum. Mol. Genet. |volume=10 |issue= 4 |pages= 339–52 |year= 2001 |pmid= 11157797 |doi=10.1093/hmg/10.4.339 }}
*{{cite journal | author=Daniels RJ, Peden JF, Lloyd C, ''et al.'' |title=Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. |journal=Hum. Mol. Genet. |volume=10 |issue= 4 |pages= 339-52 |year= 2001 |pmid= 11157797 |doi= }}
*{{cite journal   |vauthors=Ballarè E, Persani L, Lania AG, etal |title=Mutation of somatostatin receptor type 5 in an acromegalic patient resistant to somatostatin analog treatment. |journal=J. Clin. Endocrinol. Metab. |volume=86 |issue= 8 |pages= 3809–14 |year= 2001 |pmid= 11502816 |doi=10.1210/jc.86.8.3809  }}
*{{cite journal  | author=Ballarè E, Persani L, Lania AG, ''et al.'' |title=Mutation of somatostatin receptor type 5 in an acromegalic patient resistant to somatostatin analog treatment. |journal=J. Clin. Endocrinol. Metab. |volume=86 |issue= 8 |pages= 3809-14 |year= 2001 |pmid= 11502816 |doi= }}
*{{cite journal   |vauthors=Pasquali D, Notaro A, Esposito D, etal |title=[Somatostatin receptor genes expression and effects of octreotide on orbital fibroblasts from Graves' ophthalmopathy] |journal=Minerva Endocrinol. |volume=26 |issue= 3 |pages= 175–9 |year= 2002 |pmid= 11753241 |doi=  }}
*{{cite journal | author=Pasquali D, Notaro A, Esposito D, ''et al.'' |title=[Somatostatin receptor genes expression and effects of octreotide on orbital fibroblasts from Graves' ophthalmopathy] |journal=Minerva Endocrinol. |volume=26 |issue= 3 |pages= 175-9 |year= 2002 |pmid= 11753241 |doi=  }}
*{{cite journal   |vauthors=Papotti M, Bongiovanni M, Volante M, etal |title=Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis. |journal=Virchows Arch. |volume=440 |issue= 5 |pages= 461–75 |year= 2002 |pmid= 12021920 |doi= 10.1007/s00428-002-0609-x }}
*{{cite journal | author=Papotti M, Bongiovanni M, Volante M, ''et al.'' |title=Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis. |journal=Virchows Arch. |volume=440 |issue= 5 |pages= 461-75 |year= 2002 |pmid= 12021920 |doi= 10.1007/s00428-002-0609-x }}
}}
}}
{{refend}}
{{refend}}


==External links==
==External links==
* [http://www.iuphar-db.org/GPCR/ChapterMenuForward?chapterID=1298 IUPHAR Receptor Database - Somatostatin Receptors]
*{{cite web | url = http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2435 | title = Somatostatin Receptors: sst<sub>5</sub> | accessdate = | date = | format = | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | pages = | language = | archiveurl = | archivedate = | quote = }}
* {{MeshName|somatostatin+receptor+5}}
* {{MeshName|somatostatin+receptor+5}}


{{G protein-coupled receptors}}
{{G protein-coupled receptors}}
{{membrane-protein-stub}}
{{GH/IGF-1 axis signaling modulators}}
{{NLM content}}
{{NLM content}}
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[[Category:G protein coupled receptors]]
[[Category:G protein coupled receptors]]
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{{transmembranereceptor-stub}}

Revision as of 00:33, 27 October 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
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View/Edit Human

Somatostatin receptor type 5 is a protein that in humans is encoded by the SSTR5 gene.[1]

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR5 is a member of the superfamily of receptors having seven transmembrane segments.[2]

See also

References

  1. ↑ Takeda J, Fernald AA, Yamagata K, Le Beau MM, Bell GI (Aug 1995). "Localization of human somatostatin receptor 5 gene (SSTR5) to chromosome band 16p13.3 by fluorescence in situ hybridization". Genomics. 26 (3): 638–9. doi:10.1016/0888-7543(95)80195-R. PMID 7607700.
  2. ↑ "Entrez Gene: SSTR5 somatostatin receptor 5".

Further reading

  • Yamada Y, Post SR, Wang K, et al. (1992). "Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney". Proc. Natl. Acad. Sci. U.S.A. 89 (1): 251–5. doi:10.1073/pnas.89.1.251. PMC 48214. PMID 1346068.
  • Montminy MR, Goodman RH, Horovitch SJ, Habener JF (1984). "Primary structure of the gene encoding rat preprosomatostatin". Proc. Natl. Acad. Sci. U.S.A. 81 (11): 3337–40. doi:10.1073/pnas.81.11.3337. PMC 345502. PMID 6145156.
  • Panetta R, Greenwood MT, Warszynska A, et al. (1994). "Molecular cloning, functional characterization, and chromosomal localization of a human somatostatin receptor (somatostatin receptor type 5) with preferential affinity for somatostatin-28". Mol. Pharmacol. 45 (3): 417–27. PMID 7908405.
  • O'Carroll AM, Raynor K, Lolait SJ, Reisine T (1994). "Characterization of cloned human somatostatin receptor SSTR5". Mol. Pharmacol. 46 (2): 291–8. PMID 8078491.
  • Yamada Y, Kagimoto S, Kubota A, et al. (1993). "Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype". Biochem. Biophys. Res. Commun. 195 (2): 844–52. doi:10.1006/bbrc.1993.2122. PMID 8373420.
  • Yamada Y, Stoffel M, Espinosa R, et al. (1993). "Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms". Genomics. 15 (2): 449–52. doi:10.1006/geno.1993.1088. PMID 8449518.
  • Fukusumi S, Kitada C, Takekawa S, et al. (1997). "Identification and characterization of a novel human cortistatin-like peptide". Biochem. Biophys. Res. Commun. 232 (1): 157–63. doi:10.1006/bbrc.1997.6252. PMID 9125122.
  • Ain KB, Taylor KD, Tofiq S, Venkataraman G (1997). "Somatostatin receptor subtype expression in human thyroid and thyroid carcinoma cell lines". J. Clin. Endocrinol. Metab. 82 (6): 1857–62. doi:10.1210/jc.82.6.1857. PMID 9177396.
  • de Lecea L, Ruiz-Lozano P, Danielson PE, et al. (1997). "Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin". Genomics. 42 (3): 499–506. doi:10.1006/geno.1997.4763. PMID 9205124.
  • Jaïs P, Terris B, Ruszniewski P, et al. (1997). "Somatostatin receptor subtype gene expression in human endocrine gastroentero-pancreatic tumours". Eur. J. Clin. Invest. 27 (8): 639–44. doi:10.1046/j.1365-2362.1997.1740719.x. PMID 9279525.
  • Hukovic N, Panetta R, Kumar U, et al. (1998). "The cytoplasmic tail of the human somatostatin receptor type 5 is crucial for interaction with adenylyl cyclase and in mediating desensitization and internalization". J. Biol. Chem. 273 (33): 21416–22. doi:10.1074/jbc.273.33.21416. PMID 9694905.
  • Sharma K, Patel YC, Srikant CB (1999). "C-terminal region of human somatostatin receptor 5 is required for induction of Rb and G1 cell cycle arrest". Mol. Endocrinol. 13 (1): 82–90. doi:10.1210/me.13.1.82. PMID 9892014.
  • Kumar U, Sasi R, Suresh S, et al. (1999). "Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis". Diabetes. 48 (1): 77–85. doi:10.2337/diabetes.48.1.77. PMID 9892225.
  • Rocheville M, Lange DC, Kumar U, et al. (2000). "Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers". J. Biol. Chem. 275 (11): 7862–9. doi:10.1074/jbc.275.11.7862. PMID 10713101.
  • Rocheville M, Lange DC, Kumar U, et al. (2000). "Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity". Science. 288 (5463): 154–7. doi:10.1126/science.288.5463.154. PMID 10753124.
  • Daniels RJ, Peden JF, Lloyd C, et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16". Hum. Mol. Genet. 10 (4): 339–52. doi:10.1093/hmg/10.4.339. PMID 11157797.
  • Ballarè E, Persani L, Lania AG, et al. (2001). "Mutation of somatostatin receptor type 5 in an acromegalic patient resistant to somatostatin analog treatment". J. Clin. Endocrinol. Metab. 86 (8): 3809–14. doi:10.1210/jc.86.8.3809. PMID 11502816.
  • Pasquali D, Notaro A, Esposito D, et al. (2002). "[Somatostatin receptor genes expression and effects of octreotide on orbital fibroblasts from Graves' ophthalmopathy]". Minerva Endocrinol. 26 (3): 175–9. PMID 11753241.
  • Papotti M, Bongiovanni M, Volante M, et al. (2002). "Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis". Virchows Arch. 440 (5): 461–75. doi:10.1007/s00428-002-0609-x. PMID 12021920.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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