Complex locus A1BG and ZNF497: Difference between revisions
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Created page with " ==Alpha-1-B glycoprotein== # Gene ID: 1 is Alpha-1-B glycoprotein, a 54.3 kDa protein in humans that is encoded by the A1BG gene.<ref name=RefSeqJuly2008>{{ cite..." |
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==ZSCAN22== | |||
# Gene ID: 342945 is ZSCAN22 zinc finger and SCAN domain containing 22.<ref name=HGNC2019>{{ cite web | |||
|author=HGNC2019 | |||
|title=ZSCAN22 zinc finger and SCAN domain containing 22 [ Homo sapiens (human) ] | |||
|publisher=National Center for Biotechnology Information | |||
|location=U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda MD, 20894 USA | |||
|date=10 December 2019 | |||
|url=https://www.ncbi.nlm.nih.gov/gene/342945 | |||
|accessdate=2019-12-18 }}</ref> | |||
# is MIR6806 | |||
==Alpha-1-B glycoprotein== | ==Alpha-1-B glycoprotein== | ||
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The gene contains 20 distinct [[introns]].<ref name=AceView>{{cite web|title=AceView: A1BG|url=https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?db=human&term=a1bg&submit=Go|accessdate=May 11, 2013}}</ref> [[Transcription (genetics)|Transcription]] produces 15 different [[mRNAs]], 10 [[alternatively spliced]] variants and 5 unspliced forms.<ref name="AceView"/> There are 4 probable alternative [[Promoter (genetics)|promoters]], 4 non overlapping alternative last [[exons]] and 7 validated alternative [[polyadenylation]] sites.<ref name="AceView"/> The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of 4 cassette exons, overlapping exons with different boundaries, splicing versus retention of 3 introns.<ref name="AceView"/> | The gene contains 20 distinct [[introns]].<ref name=AceView>{{cite web|title=AceView: A1BG|url=https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?db=human&term=a1bg&submit=Go|accessdate=May 11, 2013}}</ref> [[Transcription (genetics)|Transcription]] produces 15 different [[mRNAs]], 10 [[alternatively spliced]] variants and 5 unspliced forms.<ref name="AceView"/> There are 4 probable alternative [[Promoter (genetics)|promoters]], 4 non overlapping alternative last [[exons]] and 7 validated alternative [[polyadenylation]] sites.<ref name="AceView"/> The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of 4 cassette exons, overlapping exons with different boundaries, splicing versus retention of 3 introns.<ref name="AceView"/> | ||
2. A1BG-AS1 | |||
==ZNF497== | ==ZNF497== | ||
Revision as of 21:27, 18 December 2019
ZSCAN22
- Gene ID: 342945 is ZSCAN22 zinc finger and SCAN domain containing 22.[1]
- is MIR6806
Alpha-1-B glycoprotein
- Gene ID: 1 is Alpha-1-B glycoprotein, a 54.3 kDa protein in humans that is encoded by the A1BG gene.[2] The protein encoded by this gene is a plasma glycoprotein of unknown function. The protein shows sequence similarity to the variable regions of some immunoglobulin supergene family member proteins. Patients who have pancreatic ductal adenocarcinoma show an overexpression of A1BG in pancreatic juice.[3]
The gene contains 20 distinct introns.[4] Transcription produces 15 different mRNAs, 10 alternatively spliced variants and 5 unspliced forms.[4] There are 4 probable alternative promoters, 4 non overlapping alternative last exons and 7 validated alternative polyadenylation sites.[4] The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of 4 cassette exons, overlapping exons with different boundaries, splicing versus retention of 3 introns.[4]
2. A1BG-AS1
ZNF497
- Gene ID: 162968 is ZNF497 zinc finger protein 497.
See also
References
- ↑ HGNC2019 (10 December 2019). "ZSCAN22 zinc finger and SCAN domain containing 22 [ Homo sapiens (human) ]". U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda MD, 20894 USA: National Center for Biotechnology Information. Retrieved 2019-12-18.
- ↑ RefSeqJuly2008 (10 December 2019). "A1BG alpha-1-B glycoprotein [ Homo sapiens (human) ]". U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda MD, 20894 USA: National Center for Biotechnology Information. Retrieved 2019-12-18.
- ↑ Tian M, Cui YZ, Song GH, Zong MJ, Zhou XY, Chen Y, Han JX (2008). "Proteomic analysis identifies MMP-9, DJ-1 and A1BG as overexpressed proteins in pancreatic juice from pancreatic ductal adenocarcinoma patients". BMC Cancer. 8: 241. doi:10.1186/1471-2407-8-241. PMC 2528014. PMID 18706098.
- ↑ 4.0 4.1 4.2 4.3 "AceView: A1BG". Retrieved May 11, 2013.