Peroxisome proliferator hormone response element gene transcriptions: Difference between revisions
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Created page with "{{AE}} Henry A. Hoff Peroxisome proliferator hormone response elements (PPREs) consensus sequences are AGGGGA and TCCCCT.<ref name=Yao>{{ cite journal | vauthors = Yao EF, De..." |
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==Consensus sequences== | ==Consensus sequences== | ||
"After activation by ligands, PPARs/RXRs heterodimers bind to PPRE consensus sequence (AGGTCANAGGTCA) in the promoter of their target genes."<ref name=You>{{ cite journal | |||
|author=Mengli You, Shuping Yuan, Juanjuan Shi, Yongzhong Hou | |||
|title=PPARδ signaling regulates colorectal cancer | |||
|journal=Current Pharmaceutical Design | |||
|date=1 June 2015 | |||
|volume=21 | |||
|issue=21 | |||
|pages=2956-2959 | |||
|url=https://www.ingentaconnect.com/content/ben/cpd/2015/00000021/00000021/art00006#expand/collapse | |||
|arxiv= | |||
|bibcode= | |||
|doi=10.2174/1381612821666150514104035 | |||
|pmid=26004416 | |||
|accessdate=10 September 2020 }}</ref> | |||
The DNA consensus sequence is AGGTCANAGGTCA, with N being any nucleotide. | The DNA consensus sequence is AGGTCANAGGTCA, with N being any nucleotide. |
Revision as of 04:46, 11 September 2020
Associate Editor(s)-in-Chief: Henry A. Hoff
Peroxisome proliferator hormone response elements (PPREs) consensus sequences are AGGGGA and TCCCCT.[1]
Human genes
Consensus sequences
"After activation by ligands, PPARs/RXRs heterodimers bind to PPRE consensus sequence (AGGTCANAGGTCA) in the promoter of their target genes."[2]
The DNA consensus sequence is AGGTCANAGGTCA, with N being any nucleotide.
Samplings
Copying the apparent consensus sequence for the PPRE (AGGGGA) and putting it in "⌘F" finds none located between ZSCAN22 or three between ZNF497 and A1BG as can be found by the computer programs.
See also
References
- ↑ Yao EF, Denison MS (June 1992). "DNA sequence determinants for binding of transformed Ah receptor to a dioxin-responsive enhancer". Biochemistry. 31 (21): 5060–7. doi:10.1021/bi00136a019. PMID 1318077.
- ↑ Mengli You, Shuping Yuan, Juanjuan Shi, Yongzhong Hou (1 June 2015). "PPARδ signaling regulates colorectal cancer". Current Pharmaceutical Design. 21 (21): 2956–2959. doi:10.2174/1381612821666150514104035. PMID 26004416. Retrieved 10 September 2020.