P53 response element gene transcriptions: Difference between revisions

Revision as of 04:46, 6 October 2020

Associate Editor(s)-in-Chief: Henry A. Hoff

"The p53 REs are defined by two closely spaced decameric half-sites [consensus sequence: 5′-(RRRCWWGYYY)n(RRRCWWGYYY)-3′; R = A,G; W = A,T; Y = C,T; n = spacer of length 0–20 base pairs (bp)], and hundreds of them have been validated in human and mouse (1)."^[1]

"According to EMSA binding experiments, all core sequences CAGG and CGTG and their palindrome sequences CCTG and CACG can be bound by p63 [18]. TAACATGTTT or TAACTTGTAT or TAACCTGTAT or TAACGTGTAT bound to p63 much more strongly than AGGCATGATG or GAGCTTGATT or GACCCTGACC or CCCCGTGCAC in EMSA experiments [21]. Therefore, p63 prefers AT-rich flanking sequences rather than general GC rich in purine (Pu) and pyrimidine (Py) bases that comprise the flanking sequence for p53 or p73 [...] [21]."^[2]

Human genes

Consensus sequences

An apparent consensus sequence for the p53RE is (A/G)(A/G)(A/G)C(A/T)(A/T)G(C/T)(C/T)(C/T).

Samplings

Copying an apparent consensus sequence for the p53RE (GGGCATGCCT) and putting it in "⌘F" finds none located between ZSCAN22 and none between ZNF497 and A1BG as can be found by the computer programs.

Copying an apparent core consensus sequence for the p53RE (CAGG) and putting it in "⌘F" finds three located between ZSCAN22 and 49 between ZNF497 and A1BG as can be found by the computer programs.

Copying an apparent core consensus sequence for the p53RE (CGTG) and putting it in "⌘F" finds 27 located between ZSCAN22 and eleven between ZNF497 and A1BG as can be found by the computer programs.

Copying an apparent consensus sequence for the p53RE (TAACATGTTT) and putting it in "⌘F" finds none located between ZSCAN22 and none between ZNF497 and A1BG as can be found by the computer programs.

Copying an apparent consensus sequence for the p53RE (TAACTTGTAT) and putting it in "⌘F" finds none located between ZSCAN22 and none between ZNF497 and A1BG as can be found by the computer programs.

Copying an apparent consensus sequence for the p53RE (TAACCTGTAT) and putting it in "⌘F" finds none located between ZSCAN22 and none between ZNF497 and A1BG as can be found by the computer programs.

Copying an apparent consensus sequence for the p53RE (TAACGTGTAT) and putting it in "⌘F" finds none located between ZSCAN22 and none between ZNF497 and A1BG as can be found by the computer programs.

Copying an apparent consensus sequence for the p53RE (AGGCATGATG) and putting it in "⌘F" finds none located between ZSCAN22 and none between ZNF497 and A1BG as can be found by the computer programs.

Copying an apparent consensus sequence for the p53RE (GAGCTTGATT) and putting it in "⌘F" finds none located between ZSCAN22 and none between ZNF497 and A1BG as can be found by the computer programs.

Copying an apparent consensus sequence for the p53RE (GACCCTGACC) and putting it in "⌘F" finds none located between ZSCAN22 and none between ZNF497 and A1BG as can be found by the computer programs.

Copying an apparent consensus sequence for the p53RE (CCCCGTGCAC) and putting it in "⌘F" finds none located between ZSCAN22 and none between ZNF497 and A1BG as can be found by the computer programs.

References

↑ Xiaojun Zhang, Ana Carolina Dantas Machado, Yuan Ding, Yongheng Chen, Yan Lu, Yankun Duan, Kenneth W. Tham, Lin Chen, Remo Rohs, Peter Z. Qin (1 February 2014). "Conformations of p53 response elements in solution deduced using site-directed spin labeling and Monte Carlo sampling". Nucleic Acids Research. 42 (4): 2789–2797. doi:10.1093/nar/gkt1219. PMID 24293651. Retrieved 28 August 2020.
↑ Bi-He Cai, Chung-Faye Chao, Hsiang-Chi Huang, Hsueh-Yi Lee, Reiji Kannagi, and Jang-Yi Chen (27 July 2019). "Roles of p53 Family Structure and Function in Non-Canonical Response Element Binding and Activation". International Journal of Molecular Sciences. 20 (15): 3681–3700. doi:10.3390/ijms20153681. Retrieved 5 October 2020.

External links

[XZhang2014-1] Xiaojun Zhang, Ana Carolina Dantas Machado, Yuan Ding, Yongheng Chen, Yan Lu, Yankun Duan, Kenneth W. Tham, Lin Chen, Remo Rohs, Peter Z. Qin (1 February 2014). "Conformations of p53 response elements in solution deduced using site-directed spin labeling and Monte Carlo sampling". Nucleic Acids Research. 42 (4): 2789–2797. doi:10.1093/nar/gkt1219. PMID 24293651. Retrieved 28 August 2020.

[Cai-2] Bi-He Cai, Chung-Faye Chao, Hsiang-Chi Huang, Hsueh-Yi Lee, Reiji Kannagi, and Jang-Yi Chen (27 July 2019). "Roles of p53 Family Structure and Function in Non-Canonical Response Element Binding and Activation". International Journal of Molecular Sciences. 20 (15): 3681–3700. doi:10.3390/ijms20153681. Retrieved 5 October 2020.

[1]

[2]

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transcriptions Gcn4p gene transcriptions Gcr1p gene transcriptions Gene expressions General factor II D gene transcriptions General regulatory factors General transcription factor II A gene transcriptions General transcription factor II B gene transcriptions General transcription factor II D gene transcriptions General transcription factor II F gene transcriptions General transcription factor II H gene transcriptions General transcription factor gene transcriptions Gene transcriptions GGC triplet gene transcriptions Gibberellin responsive element gene transcriptions GLM box gene transcriptions Glucocorticoid response element gene transcriptions Grainy head gene transcriptions Grainy head transcription factor gene transcriptions Growth hormone response element gene transcriptions GT boxes Hac1p gene transcriptions Hair color gene expressions H and ACA box gene transcriptions H box gene transcriptions Heat-responsive element gene transcriptions Heat shock elements Hex sequence gene transcriptions HMG box gene transcriptions HNF gene transcriptions Homeobox gene transcriptions Hsf1p gene transcriptions HY box gene transcriptions Hybrid C, A boxes Hybrid C, G boxes Hybrid C, T boxes Hypoxia-inducible factor gene transcriptions Hypoxia response elements I box gene transcriptions Immunoglobulin like domain containing family Initiator element gene transcriptions Initiator-like element gene transcriptions Inositol/choline-responsive elements Interaction gene transcriptions Interferon regulatory factors Inverse copy gene transcriptions Jasmonic acid-responsive element gene transcriptions K-boxes Kozak sequence gene transcriptions Kruppel-associated box gene transcriptions Krüppel-like factor gene transcriptions L box gene transcriptions Leu3 gene transcriptions M35 box gene transcriptions MADS box gene transcriptions Maf recognition element gene transcriptions M box gene transcriptions M-CAT boxes Mcm1 regulatory factor gene transcriptions Met3 gene transcriptions Met31p box gene transcriptions Metal responsive element gene transcriptions Middle sporulation element gene transcriptions Mig1p gene transcriptions Model samplings Motif ten element gene transcriptions Msn2,4p gene transcriptions Musashi binding element gene transcriptions MYB recognition element gene transcriptions Myelocytomatosis transcription factor gene transcriptions Myocyte enhancer factor gene transcriptions N-boxes Nanos/Pumilio response element Ndt80p gene transcriptions Nuclear factor 1 Nuclear factor 𝜿B Nuclear factor gene transcriptions Nuclear factor of activated T cell gene transcriptions (NFAT) Nuclear factor Y gene transcriptions Nutrient-sensing response element gene transcriptions Oaf1p gene transcriptions ORE1 binding site gene transcriptions p53 response element gene transcriptions P63 DNA-binding site gene transcriptions P box gene transcriptions Pdr1,3p gene transcriptions Peroxisome proliferator hormone response element gene transcriptions Phosphate starvation-response transcription factor gene transcriptions Pollen1 element gene transcriptions Polycomb response element gene transcriptions Preinitiation complex Preinitiation complex gene transcriptions Pribnow box gene transcriptions Prolamin box gene transcriptions Promoter gene transcriptions Proximal promoter gene transcriptions Promoter occurrence gene transcriptions Pyrimidine box gene transcriptions Q element gene transcriptions Rap1 regulatory factor gene transcriptions Reb1 general regulatory factor gene transcriptions Retinoblastoma control element gene transcriptions Retinoic acid response element gene transcriptions Rgt1p gene transcriptions Rlm1p gene transcriptions RNA polymerase II gene transcriptions RNA polymerase II holoenzyme complex Root specific element gene transcriptions ROR-response element gene transcriptions Rox1p gene transcriptions Rpn4p gene transcriptions R response element gene transcriptions SARE gene transcriptions Seed-specific element gene transcriptions Serum response element gene transcriptions Servenius sequence gene transcriptions Shoot specific element gene transcriptions Shue boxes Sip4p gene transcriptions Smp1p gene transcriptions Sp1 (Berberich) elements Sp1 gene transcriptions Spaceflight gene expressions Specificity protein gene transcriptions STAT gene transcriptions Ste12p gene transcriptions Sterol response element gene transcriptions Sucrose box gene transcriptions Synaptic Activity-Responsive Elements TACTAAC box gene transcriptions TAGteam gene transcriptions Tapetum box gene transcriptions TATA binding protein associated factor gene transcriptions TATA binding protein gene transcriptions TATA box actin/cytoskeleton/contractile family TATA box albumin family TATA box aldolase family TATA box alkaline phosphatase family TATA box annexin family TATA box cytochrome superfamily TATA box gene transcriptions TATA box heat shock family TATA box histone family TATA box human genes TATA box keratin family TATA box lipase family TATA box peptidase family TATA box platelet-derived growth factor family TATA box selenium-binding family TATA box serine protease family TATA box serpin superfamily TATA box transforming growth factor superfamily TATA box trefoil family TATA box tumor necrosis factor superfamily TATA box zinc metalloenzyme family TAT box gene transcriptions TATC box gene transcriptions Tbf1 regulatory factor gene transcriptions T box gene transcriptions TCCACCATA element gene transcriptions TC element gene transcriptions TCT gene transcriptions TEA consensus sequence gene transcriptions Tec1p gene transcriptions Telomeric repeat DNA-binding factor gene transcriptions Tetradecanoylphorbol-13-acetate response element gene transcriptions TGF-β control elements (TCEs) TGF-β inhibitory elements (TIEs) Thyroid hormone response element gene transcriptions Transcriptional regulation Transcription bubble gene transcriptions Transcription factor gene transcriptions Transcription factor 3 gene transcriptions Transcription factory gene transcriptions Transcription start site gene transcriptions Translational control sequence gene transcriptions Tryptophan residue U box gene transcriptions Unfolded protein response element gene transcriptions Upstream repressor site 1 Upstream response element gene transcriptions Upstream stimulatory factor gene transcriptions UTR promoter gene transcriptions V and P box gene transcriptions V box gene transcriptions Vhr1p gene transcriptions Vitamin D response element gene transcriptions W box gene transcriptions X box gene transcriptions Xbp1p gene transcriptions X core promoter element gene transcriptions Xenobiotic response element gene transcriptions Xenobiotic responsive element gene transcriptions Yap1p,2p gene transcriptions Y box gene transcriptions YY1 gene transcriptions Zap1p gene transcriptions Z box gene transcriptions Zinc responsive element gene transcriptions

P53 response element gene transcriptions: Difference between revisions

Revision as of 04:46, 6 October 2020

Contents

Human genes

Consensus sequences

Samplings

See also

References

External links

Navigation menu

P53 response element gene transcriptions: Difference between revisions

Revision as of 04:46, 6 October 2020

Human genes

Consensus sequences

Samplings

See also

References

External links

Navigation menu

Search