Endoplasmic reticulum stress response element gene transcriptions: Difference between revisions
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Copying an apparent consensus sequence of CCAAT and putting it in "⌘F" finds none located between ZSCAN22 and A1BG on the negative strand and finds one on the positive strand but CCAAT-1A-2T-3T-4T5T-6A-7A-8A-9GT finds none and CCAAT occurs once between ZNF497 and A1BG but CCAAT-1G-2G-3G-4C-5T-6G-7A-8A-9AC finds none between ZNF497 and A1BG on the negative strand and CCAAT occurs once between ZNF497 and A1BG but CCAAT-1A-2C-3T-4G-5A-6A-7G-8T-9CCG finds none on the positive strand as can be found by the computer programs. | Copying an apparent consensus sequence of CCAAT and putting it in "⌘F" finds none located between ZSCAN22 and A1BG on the negative strand and finds one on the positive strand but CCAAT-1A-2T-3T-4T5T-6A-7A-8A-9GT finds none and CCAAT occurs once between ZNF497 and A1BG but CCAAT-1G-2G-3G-4C-5T-6G-7A-8A-9AC finds none between ZNF497 and A1BG on the negative strand and CCAAT occurs once between ZNF497 and A1BG but CCAAT-1A-2C-3T-4G-5A-6A-7G-8T-9CCG finds none on the positive strand as can be found by the computer programs. | ||
For the Basic programs testing consensus sequence 5'-CCAAT-3' (starting with SuccessablesERSE.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found: | |||
# negative strand, negative direction, looking for 5'-AAAAAAAA-3', 0. | |||
# negative strand, positive direction, looking for 5'-AAAAAAAA-3', 0. | |||
# positive strand, negative direction, looking for 5'-AAAAAAAA-3', 0. | |||
# positive strand, positive direction, looking for 5'-AAAAAAAA-3', 0. | |||
# complement, negative strand, negative direction, looking for 5'-TTTTTTTT-3', 0. | |||
# complement, negative strand, positive direction, looking for 5'-TTTTTTTT-3', 0. | |||
# complement, positive strand, negative direction, looking for 5'-TTTTTTTT-3', 0. | |||
# complement, positive strand, positive direction, looking for 5'-TTTTTTTT-3', 0. | |||
# inverse complement, negative strand, negative direction, looking for 5'-TTTTTTTT-3', 0. | |||
# inverse complement, negative strand, positive direction, looking for 5'-TTTTTTTT-3', 0. | |||
# inverse complement, positive strand, negative direction, looking for 5'-TTTTTTTT-3', 0. | |||
# inverse complement, positive strand, positive direction, looking for 5'-TTTTTTTT-3', 0. | |||
# inverse negative strand, negative direction, looking for 5'-AAAAAAAA-3', 0. | |||
# inverse negative strand, positive direction, looking for 5'-AAAAAAAA-3', 0. | |||
# inverse positive strand, negative direction, looking for 5'-AAAAAAAA-3', 0. | |||
# inverse positive strand, positive direction, looking for 5'-AAAAAAAA-3', 0. | |||
===ERSE core promoters=== | |||
{{main|Core promoter gene transcriptions}} | |||
===ERSE proximal promoters=== | |||
{{main|Proximal promoter gene transcriptions}} | |||
===ERSE distal promoters=== | |||
{{main|Distal promoter gene transcriptions}} | |||
==See also== | ==See also== |
Revision as of 19:20, 21 December 2020
Associate Editor(s)-in-Chief: Henry A. Hoff
Human genes
Consensus sequences
"The released aminoterminal of ATF6 (ATF6-N) then migrates to the nucleus and binds to the ER stress response element (ERSE) containing the consensus sequence CCAAT-N9-CCACG to activate genes encoding ER chaperones, ERAD components, and XBP1 (Chen et al., 2010; Yamamoto et al., 2004; Yoshida et al., 2001)."[1]
Samplings
Copying an apparent consensus sequence of CCAAT and putting it in "⌘F" finds none located between ZSCAN22 and A1BG on the negative strand and finds one on the positive strand but CCAAT-1A-2T-3T-4T5T-6A-7A-8A-9GT finds none and CCAAT occurs once between ZNF497 and A1BG but CCAAT-1G-2G-3G-4C-5T-6G-7A-8A-9AC finds none between ZNF497 and A1BG on the negative strand and CCAAT occurs once between ZNF497 and A1BG but CCAAT-1A-2C-3T-4G-5A-6A-7G-8T-9CCG finds none on the positive strand as can be found by the computer programs.
For the Basic programs testing consensus sequence 5'-CCAAT-3' (starting with SuccessablesERSE.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:
- negative strand, negative direction, looking for 5'-AAAAAAAA-3', 0.
- negative strand, positive direction, looking for 5'-AAAAAAAA-3', 0.
- positive strand, negative direction, looking for 5'-AAAAAAAA-3', 0.
- positive strand, positive direction, looking for 5'-AAAAAAAA-3', 0.
- complement, negative strand, negative direction, looking for 5'-TTTTTTTT-3', 0.
- complement, negative strand, positive direction, looking for 5'-TTTTTTTT-3', 0.
- complement, positive strand, negative direction, looking for 5'-TTTTTTTT-3', 0.
- complement, positive strand, positive direction, looking for 5'-TTTTTTTT-3', 0.
- inverse complement, negative strand, negative direction, looking for 5'-TTTTTTTT-3', 0.
- inverse complement, negative strand, positive direction, looking for 5'-TTTTTTTT-3', 0.
- inverse complement, positive strand, negative direction, looking for 5'-TTTTTTTT-3', 0.
- inverse complement, positive strand, positive direction, looking for 5'-TTTTTTTT-3', 0.
- inverse negative strand, negative direction, looking for 5'-AAAAAAAA-3', 0.
- inverse negative strand, positive direction, looking for 5'-AAAAAAAA-3', 0.
- inverse positive strand, negative direction, looking for 5'-AAAAAAAA-3', 0.
- inverse positive strand, positive direction, looking for 5'-AAAAAAAA-3', 0.
ERSE core promoters
ERSE proximal promoters
ERSE distal promoters
See also
References
- ↑ Jae-Seon So (31 August 2018). "Roles of Endoplasmic Reticulum Stress in Immune Responses". Molecules and Cells. 41 (8): 705–16. doi:10.14348/molcells.2018.0241. PMID 30078231. Retrieved 5 September 2020.