P63 DNA-binding site gene transcriptions: Difference between revisions
Created page with "{{AE}} Henry A. Hoff "p63 bound preferentially to DNA fragments conforming to the 20 bp sequence 5'-RRRC(A/G)(A/T)GYYYRRRC(A/T)(C/T)GYYY-3'."<ref name=Perez>{{ cite journal |..." |
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==Samplings== | ==Samplings== | ||
{{main|Model samplings}} | |||
Copying an apparent consensus sequence for the P63 (GAGCGAGCCT) and putting it in "⌘F" finds none located between ZSCAN22 and one between ZNF497 and A1BG as can be found by the computer programs. | |||
For the Basic programs testing consensus sequence (A/G)(A/G)(A/G)C(A/G)(A/T)G(C/T)(C/T)(C/T)(A/G)(A/G)(A/G)C(A/T)(C/T)G(C/T)(C/T)(C/T) (starting with SuccessablesP63.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found: | |||
# negative strand, negative direction, looking for (A/G)(A/G)(A/G)C(A/G)(A/T)G(C/T)(C/T)(C/T)(A/G)(A/G)(A/G)C(A/T)(C/T)G(C/T)(C/T)(C/T), 0. | |||
# positive strand, negative direction, looking for AAAAAAAA, 0. | |||
# positive strand, positive direction, looking for AAAAAAAA, 0. | |||
# negative strand, positive direction, looking for AAAAAAAA, 0. | |||
# complement, negative strand, negative direction, looking for TTTTTTTT, 0. | |||
# complement, positive strand, negative direction, looking for TTTTTTTT, 0. | |||
# complement, positive strand, positive direction, looking for TTTTTTTT, 0. | |||
# complement, negative strand, positive direction, looking for TTTTTTTT, 0. | |||
# inverse complement, negative strand, negative direction, looking for TTTTTTTT, 0. | |||
# inverse complement, positive strand, negative direction, looking for TTTTTTTT, 0. | |||
# inverse complement, positive strand, positive direction, looking for TTTTTTTT, 0. | |||
# inverse complement, negative strand, positive direction, looking for TTTTTTTT, 0. | |||
# inverse negative strand, negative direction, looking for AAAAAAAA, 0. | |||
# inverse positive strand, negative direction, looking for AAAAAAAA, 0. | |||
# inverse positive strand, positive direction, looking for AAAAAAAA, 0. | |||
# inverse negative strand, positive direction, looking for AAAAAAAA, 0. | |||
===AAA UTRs=== | |||
{{main|UTR promoter gene transcriptions}} | |||
===AAA core promoters=== | |||
{{main|Core promoter gene transcriptions}} | |||
===AAA proximal promoters=== | |||
{{main|Proximal promoter gene transcriptions}} | |||
===AAA distal promoters=== | |||
{{main|Distal promoter gene transcriptions}} | |||
==See also== | ==See also== |
Revision as of 17:47, 13 February 2021
Associate Editor(s)-in-Chief: Henry A. Hoff
"p63 bound preferentially to DNA fragments conforming to the 20 bp sequence 5'-RRRC(A/G)(A/T)GYYYRRRC(A/T)(C/T)GYYY-3'."[1]
Human genes
Consensus sequences
The apparent consensus sequence is (A/G)(A/G)(A/G)C(A/G)(A/T)G(C/T)(C/T)(C/T).
Samplings
Copying an apparent consensus sequence for the P63 (GAGCGAGCCT) and putting it in "⌘F" finds none located between ZSCAN22 and one between ZNF497 and A1BG as can be found by the computer programs.
For the Basic programs testing consensus sequence (A/G)(A/G)(A/G)C(A/G)(A/T)G(C/T)(C/T)(C/T)(A/G)(A/G)(A/G)C(A/T)(C/T)G(C/T)(C/T)(C/T) (starting with SuccessablesP63.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:
- negative strand, negative direction, looking for (A/G)(A/G)(A/G)C(A/G)(A/T)G(C/T)(C/T)(C/T)(A/G)(A/G)(A/G)C(A/T)(C/T)G(C/T)(C/T)(C/T), 0.
- positive strand, negative direction, looking for AAAAAAAA, 0.
- positive strand, positive direction, looking for AAAAAAAA, 0.
- negative strand, positive direction, looking for AAAAAAAA, 0.
- complement, negative strand, negative direction, looking for TTTTTTTT, 0.
- complement, positive strand, negative direction, looking for TTTTTTTT, 0.
- complement, positive strand, positive direction, looking for TTTTTTTT, 0.
- complement, negative strand, positive direction, looking for TTTTTTTT, 0.
- inverse complement, negative strand, negative direction, looking for TTTTTTTT, 0.
- inverse complement, positive strand, negative direction, looking for TTTTTTTT, 0.
- inverse complement, positive strand, positive direction, looking for TTTTTTTT, 0.
- inverse complement, negative strand, positive direction, looking for TTTTTTTT, 0.
- inverse negative strand, negative direction, looking for AAAAAAAA, 0.
- inverse positive strand, negative direction, looking for AAAAAAAA, 0.
- inverse positive strand, positive direction, looking for AAAAAAAA, 0.
- inverse negative strand, positive direction, looking for AAAAAAAA, 0.
AAA UTRs
AAA core promoters
AAA proximal promoters
AAA distal promoters
See also
References
- ↑ C A Perez, J Ott, D J Mays & J A Pietenpol (15 November 2007). "p63 consensus DNA-binding site: identification, analysis and application into a p63MH algorithm". Oncogene. 26 (52): 7363–70. doi:10.1038/sj.onc.1210561. PMID 17563751. Retrieved 28 August 2020.