D box gene transcriptions
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Associate Editor(s)-in-Chief: Henry A. Hoff
For "box C/D snoRNAs, boxes C and D and an adjoining stem form a vital structure, known as the box C/D motif."[1]
In snoRNA U73 on the right, from the right side, the D box is AGUCY. In 5' to 3' direction, the D box is YCUGA.
Degenerate nucleotides
Main articles: Degenerate nucleotide gene transcriptions and Degenerate nucleotides
For transcription, U (in RNA) is T, Y=(C or T) and R=(A or G).
Consensus sequences
Main articles: Consensus sequence gene transcriptions and Consensus sequences
Shown in the image on the right is the D box (3'-AGUCUG-5'). Substituting T for U yields D box = 3'-AGTCTG-5' in the transcription direction on the template strand.
"Members of the box C/D snoRNA family, which are the subject of the present report, possess characteristic sequence elements known as box C (UGAUGA) and box D (GUCUGA)."[1]
See also
References
- ↑ 1.0 1.1 Dmitry A.Samarsky, Maurille J.Fournier, Robert H.Singer and Edouard Bertrand (1 July 1998). "The snoRNA box C/D motif directs nucleolar targeting and also couples snoRNA synthesis and localization" (PDF). The European Molecular Biology Organization (EMBO) Journal. 17 (13): 3747–3757. doi:10.1093/emboj/17.13.3747. PMID 9649444. Retrieved 2017-02-04.CS1 maint: Multiple names: authors list (link)