Bioinformatics tool gene transcriptions
Associate Editor(s)-in-Chief: Henry A. Hoff
Def. a "field of science in which biology, computer science, and information technology merge into a single discipline to analyse biological information using computers and statistical techniques"[1] is called bioinformatics.
Contents
Human genes
"Briefly, the mRNA sequences were obtained from the NCBI Reference Sequence Database (RefSeq) for human SIRT2 gene. The reference mRNA sequences was submitted to BLAST for comparison with the human genomic DNA sequence in the human genome database."[2]
Human promoter occurrences
"After noting the orientation of the alignment, the appropriate 5-Kb genomic DNA sequence upstream from the transcription start point corresponding to the promoter region of the gene was isolated and analyzed using a web-based bioinformatics tool TESS at http://www.cbil.upenn.edu/cgi-bin/tess/tess. Because TESS results are model-based, the potential CArG sequence was verified by both using LALIGN (http://www.ch.embnet.org/software/LALIGN_form.html) and visual confirmation."[2]
Acknowledgements
The content on this page was first contributed by: Henry A. Hoff.
See also
References
- ↑ 201.129.67.142 (6 May 2005). "bioinformatics". San Francisco, California: Wikimedia Foundation, Inc. Retrieved 23 February 2021.
- ↑ 2.0 2.1 Xiaomin Zhang, Gohar Azhar, Jeanne Y. Wei (21 December 2017). "SIRT2 gene has a classic SRE element, is a downstream target of serum response factor and is likely activated during serum stimulation". PLOS One. 12 (12): e0190011. doi:10.1371/journal.pone.0190011. Retrieved 23 February 2021.CS1 maint: Multiple names: authors list (link)
External links
- GenomeNet KEGG database
- Home - Gene - NCBI
- NCBI All Databases Search
- NCBI Site Search
- PubChem Public Chemical Database