Peroxisome proliferator hormone response element gene transcriptions
Associate Editor(s)-in-Chief: Henry A. Hoff
Peroxisome proliferator hormone response elements (PPREs) consensus sequences are AGGGGA and TCCCCT.[1]
Human genes
Consensus sequences
"After activation by ligands, PPARs/RXRs heterodimers bind to PPRE consensus sequence (AGGTCANAGGTCA) in the promoter of their target genes."[2]
The DNA consensus sequence is AGGTCANAGGTCA, with N being any nucleotide.
Samplings
Copying the apparent consensus sequence for the PPRE (AGGGGA) and putting it in "⌘F" finds none located between ZSCAN22 or three between ZNF497 and A1BG as can be found by the computer programs.
See also
References
- ↑ Yao EF, Denison MS (June 1992). "DNA sequence determinants for binding of transformed Ah receptor to a dioxin-responsive enhancer". Biochemistry. 31 (21): 5060–7. doi:10.1021/bi00136a019. PMID 1318077.
- ↑ Mengli You, Shuping Yuan, Juanjuan Shi, Yongzhong Hou (1 June 2015). "PPARδ signaling regulates colorectal cancer". Current Pharmaceutical Design. 21 (21): 2956–2959. doi:10.2174/1381612821666150514104035. PMID 26004416. Retrieved 10 September 2020.CS1 maint: Multiple names: authors list (link)