Mcm1 regulatory factor gene transcriptions

Associate Editor(s)-in-Chief: Henry A. Hoff

Human genes

Interactions

Consensus sequences

Consensus sequences: 1N2N3(A/C/T)4(A/C/T)5N6C7(C/T)8(A/C/T)9(A/C/T)10(A/T)11(A/C/T)12(A/C/T)13N14(A/G)15(C/G/T)16(A/C/T)17N18N19N.^[1]

The primary consensus sequence is apparently TT(A/T)CCNN(A/T)TNGG(A/T)AA.^[1]

Samplings

Copying a consensus regulatory element: TT(A/T)CCNN(A/T)TNGG(A/T)AA and putting the sequence in "⌘F" finds no locations for this sequence in any A1BG direction as can be found by the computer programs.

For the Basic programs testing consensus sequence TT(A/T)CCNN(A/T)TNGG(A/T)AA (starting with SuccessablesMcm.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:

negative strand, negative direction, looking for TT(A/T)CCNN(A/T)TNGG(A/T)AA, 0.
positive strand, negative direction, looking for TT(A/T)CCNN(A/T)TNGG(A/T)AA, 0.
positive strand, positive direction, looking for TT(A/T)CCNN(A/T)TNGG(A/T)AA, 0.
negative strand, positive direction, looking for TT(A/T)CCNN(A/T)TNGG(A/T)AA, 0.
complement, negative strand, negative direction, looking for TTTTTTTT, 0.
complement, positive strand, negative direction, looking for TTTTTTTT, 0.
complement, positive strand, positive direction, looking for TTTTTTTT, 0.
complement, negative strand, positive direction, looking for TTTTTTTT, 0.
inverse complement, negative strand, negative direction, looking for TTTTTTTT, 0.
inverse complement, positive strand, negative direction, looking for TTTTTTTT, 0.
inverse complement, positive strand, positive direction, looking for TTTTTTTT, 0.
inverse complement, negative strand, positive direction, looking for TTTTTTTT, 0.
inverse negative strand, negative direction, looking for AA(A/T)GGNT(A/T)NNCC(A/T)TT, 0.
inverse positive strand, negative direction, looking for AAAAAAAA, 0.
inverse positive strand, positive direction, looking for AAAAAAAA, 0.
inverse negative strand, positive direction, looking for AAAAAAAA, 0.

AAA UTR gene transcriptions

AAA core promoters

AAA proximal promoters

AAA distal promoters

References

↑ ^1.0 ^1.1 Matthew J. Rossi, William K.M. Lai and B. Franklin Pugh (21 March 2018). "Genome-wide determinants of sequence-specific DNA binding of general regulatory factors". Genome Research. 28: 497–508. doi:10.1101/gr.229518.117. PMID 29563167. Retrieved 31 August 2020.

External links

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