CCAAT/enhancer binding protein zeta: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''CCAAT/enhancer-binding protein zeta''' is a [[protein]] that in humans is encoded by the ''CEBPZ'' [[gene]].<ref name="pmid2247079">{{cite journal | vauthors = Lum LS, Sultzman LA, Kaufman RJ, Linzer DI, Wu BJ | title = A cloned human CCAAT-box-binding factor stimulates transcription from the human hsp70 promoter | journal = Mol Cell Biol | volume = 10 | issue = 12 | pages = 6709–17 | date = Jan 1991 | pmid = 2247079 | pmc = 362949 | doi =  }}</ref><ref name="pmid12534345">{{cite journal | vauthors = Uramoto H, Izumi H, Nagatani G, Ohmori H, Nagasue N, Ise T, Yoshida T, Yasumoto K, Kohno K | title = Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression | journal = Biochem J | volume = 371 | issue = Pt 2 | pages = 301–10 | date = Apr 2003 | pmid = 12534345 | pmc = 1223307 | doi = 10.1042/BJ20021646 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CEBPZ CCAAT/enhancer binding protein zeta| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10153| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
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== Interactions ==
{{GNF_Protein_box
CCAAT/enhancer binding protein zeta has been shown to [[Protein-protein interaction|interact]] with:
| image =
* [[NFYB]],<ref name = pmid11306579>{{cite journal | vauthors = Imbriano C, Bolognese F, Gurtner A, Piaggio G, Mantovani R | title = HSP-CBF is an NF-Y-dependent coactivator of the heat shock promoters CCAAT boxes | journal = J. Biol. Chem. | volume = 276 | issue = 28 | pages = 26332–9 | date = Jul 2001 | pmid = 11306579 | doi = 10.1074/jbc.M101553200 }}</ref>
| image_source =
* [[P53]],<ref name = pmid12534345/>
| PDB =  
* [[P73]]<ref name = autogenerated1>{{cite journal | vauthors = Uramoto H, Izumi H, Nagatani G, Ohmori H, Nagasue N, Ise T, Yoshida T, Yasumoto K, Kohno K | title = Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression | journal = Biochem. J. | volume = 371 | issue = Pt 2 | pages = 301–10 | date = Apr 2003 | pmid = 12534345 | pmc = 1223307 | doi = 10.1042/BJ20021646 }}</ref>
| Name = CCAAT/enhancer binding protein zeta
| HGNCid = 24218
| Symbol = CEBPZ
| AltSymbols =; CBF2; HSP-CBF
| OMIM =
| ECnumber =
| Homologene = 4210
| MGIid = 109386
| Function = {{GNF_GO|id=GO:0003677 |text = DNA binding}}  
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0006366 |text = transcription from RNA polymerase II promoter}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 10153
    | Hs_Ensembl = ENSG00000115816
    | Hs_RefseqProtein = NP_005751
    | Hs_RefseqmRNA = NM_005760
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 2
    | Hs_GenLoc_start = 37282259
    | Hs_GenLoc_end = 37312248
    | Hs_Uniprot = Q03701
    | Mm_EntrezGene = 12607
    | Mm_Ensembl = ENSMUSG00000024081
    | Mm_RefseqmRNA = NM_001024806
    | Mm_RefseqProtein = NP_001019977
    | Mm_GenLoc_db =
    | Mm_GenLoc_chr = 17
    | Mm_GenLoc_start = 78824297
    | Mm_GenLoc_end = 78842125
    | Mm_Uniprot = Q3UGK4
  }}
}}
'''CCAAT/enhancer binding protein zeta''', also known as '''CEBPZ''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CEBPZ CCAAT/enhancer binding protein zeta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10153| accessdate = }}</ref>


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== See also ==
{{PBB_Summary
| section_title =
| summary_text =
}}
 
==See also==
* [[Ccaat-enhancer-binding proteins]]
* [[Ccaat-enhancer-binding proteins]]


==References==
== References ==
{{reflist|2}}
{{reflist}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Hoeppner MA, Gilbert DJ, Copeland NG, Jenkins NA, Linzer DI, Wu B | title = Cloning and characterization of mouse CCAAT binding factor. | journal = Nucleic Acids Res. | volume = 24 | issue = 6 | pages = 1091–8 | year = 1996 | pmid = 8604343 | pmc = 145757 | doi = 10.1093/nar/24.6.1091 }}
| citations =
* {{cite journal | vauthors = Imbriano C, Bolognese F, Gurtner A, Piaggio G, Mantovani R | title = HSP-CBF is an NF-Y-dependent coactivator of the heat shock promoters CCAAT boxes. | journal = J. Biol. Chem. | volume = 276 | issue = 28 | pages = 26332–9 | year = 2001 | pmid = 11306579 | doi = 10.1074/jbc.M101553200 }}
*{{cite journal | author=Lum LS, Sultzman LA, Kaufman RJ, ''et al.'' |title=A cloned human CCAAT-box-binding factor stimulates transcription from the human hsp70 promoter. |journal=Mol. Cell. Biol. |volume=10 |issue= 12 |pages= 6709-17 |year= 1991 |pmid= 2247079 |doi=  }}
* {{cite journal | vauthors = Iouzalen N, Andreae S, Hannier S, Triebel F | title = LAP, a lymphocyte activation gene-3 (LAG-3)-associated protein that binds to a repeated EP motif in the intracellular region of LAG-3, may participate in the down-regulation of the CD3/TCR activation pathway. | journal = Eur. J. Immunol. | volume = 31 | issue = 10 | pages = 2885–91 | year = 2001 | pmid = 11592063 | doi = 10.1002/1521-4141(2001010)31:10<2885::AID-IMMU2885>3.0.CO;2-2 }}
*{{cite journal  | author=Hoeppner MA, Gilbert DJ, Copeland NG, ''et al.'' |title=Cloning and characterization of mouse CCAAT binding factor. |journal=Nucleic Acids Res. |volume=24 |issue= 6 |pages= 1091-8 |year= 1996 |pmid= 8604343 |doi= }}
* {{cite journal | vauthors = Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI | title = Directed proteomic analysis of the human nucleolus. | journal = Curr. Biol. | volume = 12 | issue = 1 | pages = 1–11 | year = 2002 | pmid = 11790298 | doi = 10.1016/S0960-9822(01)00650-9 }}
*{{cite journal | author=Imbriano C, Bolognese F, Gurtner A, ''et al.'' |title=HSP-CBF is an NF-Y-dependent coactivator of the heat shock promoters CCAAT boxes. |journal=J. Biol. Chem. |volume=276 |issue= 28 |pages= 26332-9 |year= 2001 |pmid= 11306579 |doi= 10.1074/jbc.M101553200 }}
* {{cite journal | vauthors = Milkereit P, Strauss D, Bassler J, Gadal O, Kühn H, Schütz S, Gas N, Lechner J, Hurt E, Tschochner H | title = A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits. | journal = J. Biol. Chem. | volume = 278 | issue = 6 | pages = 4072–81 | year = 2003 | pmid = 12446671 | doi = 10.1074/jbc.M208898200 }}
*{{cite journal | author=Iouzalen N, Andreae S, Hannier S, Triebel F |title=LAP, a lymphocyte activation gene-3 (LAG-3)-associated protein that binds to a repeated EP motif in the intracellular region of LAG-3, may participate in the down-regulation of the CD3/TCR activation pathway. |journal=Eur. J. Immunol. |volume=31 |issue= 10 |pages= 2885-91 |year= 2001 |pmid= 11592063 |doi= }}
* {{cite journal | vauthors = Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M | title = Nucleolar proteome dynamics. | journal = Nature | volume = 433 | issue = 7021 | pages = 77–83 | year = 2005 | pmid = 15635413 | doi = 10.1038/nature03207 }}
*{{cite journal | author=Andersen JS, Lyon CE, Fox AH, ''et al.'' |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1-11 |year= 2002 |pmid= 11790298 |doi= }}
* {{cite journal | vauthors = Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R | title = Phosphoproteome analysis of the human mitotic spindle. | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 103 | issue = 14 | pages = 5391–6 | year = 2006 | pmid = 16565220 | pmc = 1459365 | doi = 10.1073/pnas.0507066103 }}
*{{cite journal | author=Milkereit P, Strauss D, Bassler J, ''et al.'' |title=A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits. |journal=J. Biol. Chem. |volume=278 |issue= 6 |pages= 4072-81 |year= 2003 |pmid= 12446671 |doi= 10.1074/jbc.M208898200 }}
* {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | year = 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Uramoto H, Izumi H, Nagatani G, ''et al.'' |title=Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression. |journal=Biochem. J. |volume=371 |issue= Pt 2 |pages= 301-10 |year= 2003 |pmid= 12534345 |doi= 10.1042/BJ20021646 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Andersen JS, Lam YW, Leung AK, ''et al.'' |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77-83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207 }}
*{{cite journal | author=Hillier LW, Graves TA, Fulton RS, ''et al.'' |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724-31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466 }}
*{{cite journal  | author=Nousiainen M, Silljé HH, Sauer G, ''et al.'' |title=Phosphoproteome analysis of the human mitotic spindle. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391-6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
}}
{{refend}}
{{refend}}


== External links ==
== External links ==
* {{MeshName|CEBPz+protein,+human}}
* {{MeshName|CEBPz+protein,+human}}
* {{UCSC genome browser|CEBPZ}}
* {{UCSC gene details|CEBPZ}}


{{Transcription factors|g1}}
{{NLM content}}
{{NLM content}}
{{protein-stub}}
 
{{Transcription factors}}
{{DEFAULTSORT:CCAAT enhancer binding protein zeta}}
[[Category:Transcription factors]]
[[Category:Transcription factors]]
{{WikiDoc Sources}}
 
 
{{gene-2-stub}}

Latest revision as of 09:14, 30 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

CCAAT/enhancer-binding protein zeta is a protein that in humans is encoded by the CEBPZ gene.[1][2][3]

Interactions

CCAAT/enhancer binding protein zeta has been shown to interact with:

See also

References

  1. Lum LS, Sultzman LA, Kaufman RJ, Linzer DI, Wu BJ (Jan 1991). "A cloned human CCAAT-box-binding factor stimulates transcription from the human hsp70 promoter". Mol Cell Biol. 10 (12): 6709–17. PMC 362949. PMID 2247079.
  2. 2.0 2.1 Uramoto H, Izumi H, Nagatani G, Ohmori H, Nagasue N, Ise T, Yoshida T, Yasumoto K, Kohno K (Apr 2003). "Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression". Biochem J. 371 (Pt 2): 301–10. doi:10.1042/BJ20021646. PMC 1223307. PMID 12534345.
  3. "Entrez Gene: CEBPZ CCAAT/enhancer binding protein zeta".
  4. Imbriano C, Bolognese F, Gurtner A, Piaggio G, Mantovani R (Jul 2001). "HSP-CBF is an NF-Y-dependent coactivator of the heat shock promoters CCAAT boxes". J. Biol. Chem. 276 (28): 26332–9. doi:10.1074/jbc.M101553200. PMID 11306579.
  5. Uramoto H, Izumi H, Nagatani G, Ohmori H, Nagasue N, Ise T, Yoshida T, Yasumoto K, Kohno K (Apr 2003). "Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression". Biochem. J. 371 (Pt 2): 301–10. doi:10.1042/BJ20021646. PMC 1223307. PMID 12534345.

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.