GTF3A: Difference between revisions

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Latest revision as of 11:32, 9 January 2019

Transcription factor IIIA is a protein that in humans is encoded by the GTF3A gene.^[1]^[2] It was first isolated and characterized by Wolffe and Brown in 1988.

References

↑ Arakawa H, Nagase H, Hayashi N, Ogawa M, Nagata M, Fujiwara T, Takahashi E, Shin S, Nakamura Y (Jul 1995). "Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA". Cytogenetics and Cell Genetics. 70 (3–4): 235–8. doi:10.1159/000134041. PMID 7789179.
↑ "Entrez Gene: GTF3A general transcription factor IIIA".

Murphy JE, Keen JH (May 1992). "Recognition sites for clathrin-associated proteins AP-2 and AP-3 on clathrin triskelia". The Journal of Biological Chemistry. 267 (15): 10850–5. PMID 1587861.
Seifart KH, Wang L, Waldschmidt R, Jahn D, Wingender E (Jan 1989). "Purification of human transcription factor IIIA and its interaction with a chemically synthesized gene encoding human 5 S rRNA". The Journal of Biological Chemistry. 264 (3): 1702–9. PMID 2912980.
Drew PD, Nagle JW, Canning RD, Ozato K, Biddison WE, Becker KG (Jul 1995). "Cloning and expression analysis of a human cDNA homologous to Xenopus TFIIIA". Gene. 159 (2): 215–8. doi:10.1016/0378-1119(95)00145-V. PMID 7622052.
Moorefield B, Roeder RG (Aug 1994). "Purification and characterization of human transcription factor IIIA". The Journal of Biological Chemistry. 269 (33): 20857–65. PMID 8063702.
Fridell RA, Fischer U, Lührmann R, Meyer BE, Meinkoth JL, Malim MH, Cullen BR (Apr 1996). "Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev". Proceedings of the National Academy of Sciences of the United States of America. 93 (7): 2936–40. doi:10.1073/pnas.93.7.2936. PMC 39738. PMID 8610146.
Oettel S, Härtel F, Kober I, Iben S, Seifart KH (Jun 1997). "Human transcription factors IIIC2 , IIIC1 and a novel component IIIC0 fulfil different aspects of DNA binding to various pol III genes". Nucleic Acids Research. 25 (12): 2440–7. doi:10.1093/nar/25.12.2440. PMC 146769. PMID 9171097.
Moreland RJ, Dresser ME, Rodgers JS, Roe BA, Conaway JW, Conaway RC, Hanas JS (May 2000). "Identification of a transcription factor IIIA-interacting protein". Nucleic Acids Research. 28 (9): 1986–93. doi:10.1093/nar/28.9.1986. PMC 103300. PMID 10756201.
Rao DS, Chang JC, Kumar PD, Mizukami I, Smithson GM, Bradley SV, Parlow AF, Ross TS (Nov 2001). "Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors". Molecular and Cellular Biology. 21 (22): 7796–806. doi:10.1128/MCB.21.22.7796-7806.2001. PMC 99949. PMID 11604514.
Hanas JS, Hocker JR, Cheng YG, Lerner MR, Brackett DJ, Lightfoot SA, Hanas RJ, Madhusudhan KT, Moreland RJ (Jan 2002). "cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA". Gene. 282 (1–2): 43–52. doi:10.1016/S0378-1119(01)00796-X. PMID 11814676.
Weser S, Riemann J, Seifart KH, Meissner W (May 2003). "Assembly and isolation of intermediate steps of transcription complexes formed on the human 5S rRNA gene". Nucleic Acids Research. 31 (9): 2408–16. doi:10.1093/nar/gkg345. PMC 154231. PMID 12711686.
Pellikainen JM, Ropponen KM, Kataja VV, Kellokoski JK, Eskelinen MJ, Kosma VM (Nov 2004). "Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis". Clinical Cancer Research. 10 (22): 7621–8. doi:10.1158/1078-0432.CCR-04-1061. PMID 15569994.
Paing MM, Johnston CA, Siderovski DP, Trejo J (Apr 2006). "Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization". Molecular and Cellular Biology. 26 (8): 3231–42. doi:10.1128/MCB.26.8.3231-3242.2006. PMC 1446942. PMID 16581796.
Yamashita A, Takada T, Nemoto K, Yamamoto G, Torii R (Jul 2006). "Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage". FEBS Letters. 580 (17): 4121–5. doi:10.1016/j.febslet.2006.06.057. PMID 16828750.
Schwartz B, Melnikova VO, Tellez C, Mourad-Zeidan A, Blehm K, Zhao YJ, McCarty M, Adam L, Bar-Eli M (Jun 2007). "Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo". Oncogene. 26 (28): 4049–58. doi:10.1038/sj.onc.1210193. PMID 17224907.

External links

GTF3A+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This protein-related article is a stub. You can help Wikipedia by expanding it.

[pmid7789179-1] Arakawa H, Nagase H, Hayashi N, Ogawa M, Nagata M, Fujiwara T, Takahashi E, Shin S, Nakamura Y (Jul 1995). "Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA". Cytogenetics and Cell Genetics. 70 (3–4): 235–8. doi:10.1159/000134041. PMID 7789179.

[entrez-2] "Entrez Gene: GTF3A general transcription factor IIIA".

[1]

[2]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Underlinked|date=June 2016}}
-{{PBB_Controls
+{{Infobox_gene}}
-| update_page = yes
+'''Transcription factor IIIA''' is a [[protein]] that in humans is encoded by the ''GTF3A'' [[gene]].<ref name="pmid7789179">  {{cite journal | vauthors = Arakawa H, Nagase H, Hayashi N, Ogawa M, Nagata M, Fujiwara T, Takahashi E, Shin S, Nakamura Y | title = Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA | journal = Cytogenetics and Cell Genetics | volume = 70 | issue = 3-4 | pages = 235–8 | date = Jul 1995 | pmid = 7789179 | pmc =  | doi = 10.1159/000134041 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GTF3A general transcription factor IIIA| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2971| accessdate = }}</ref> It was first isolated and characterized by Wolffe and Brown in 1988.
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== References ==
-{{GNF_Protein_box
+{{reflist}}
- | image =
- | image_source =
- | PDB =
- | Name = General transcription factor IIIA
- | HGNCid = 4662
- | Symbol = GTF3A
- | AltSymbols =; AP2; TFIIIA
- | OMIM = 600860
- | ECnumber =
- | Homologene =
- | MGIid =
- | Function = {{GNF_GO|id=GO:0003677 |text = DNA binding}} {{GNF_GO|id=GO:0003709 |text = RNA polymerase III transcription factor activity}} {{GNF_GO|id=GO:0003723 |text = RNA binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
- | Component = {{GNF_GO|id=GO:0005622 |text = intracellular}} {{GNF_GO|id=GO:0005634 |text = nucleus}}
- | Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0006383 |text = transcription from RNA polymerase III promoter}} {{GNF_GO|id=GO:0009303 |text = rRNA transcription}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 2971
-    | Hs_Ensembl =
-    | Hs_RefseqProtein = NP_002088
-    | Hs_RefseqmRNA = NM_002097
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr =
-    | Hs_GenLoc_start =
-    | Hs_GenLoc_end =
-    | Hs_Uniprot =
-    | Mm_EntrezGene =
-    | Mm_Ensembl =
-    | Mm_RefseqmRNA =
-    | Mm_RefseqProtein =
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr =
-    | Mm_GenLoc_start =
-    | Mm_GenLoc_end =
-    | Mm_Uniprot =
-  }}
-}}
-'''General transcription factor IIIA''', also known as '''GTF3A''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GTF3A general transcription factor IIIA| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2971| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Further reading ==
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
-==References==
-{{reflist|2}}
-==Further reading==
 {{refbegin | 2}}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Murphy JE, Keen JH | title = Recognition sites for clathrin-associated proteins AP-2 and AP-3 on clathrin triskelia | journal = The Journal of Biological Chemistry | volume = 267 | issue = 15 | pages = 10850–5 | date = May 1992 | pmid = 1587861 | doi =  }}
-| citations =
+* {{cite journal | vauthors = Seifart KH, Wang L, Waldschmidt R, Jahn D, Wingender E | title = Purification of human transcription factor IIIA and its interaction with a chemically synthesized gene encoding human 5 S rRNA | journal = The Journal of Biological Chemistry | volume = 264 | issue = 3 | pages = 1702–9 | date = Jan 1989 | pmid = 2912980 | doi =  }}
-*{{cite journal  | author=Murphy JE, Keen JH |title=Recognition sites for clathrin-associated proteins AP-2 and AP-3 on clathrin triskelia. |journal=J. Biol. Chem. |volume=267 |issue= 15 |pages= 10850-5 |year= 1992 |pmid= 1587861 |doi=  }}
+* {{cite journal | vauthors = Drew PD, Nagle JW, Canning RD, Ozato K, Biddison WE, Becker KG | title = Cloning and expression analysis of a human cDNA homologous to Xenopus TFIIIA | journal = Gene | volume = 159 | issue = 2 | pages = 215–8 | date = Jul 1995 | pmid = 7622052 | doi = 10.1016/0378-1119(95)00145-V }}
-*{{cite journal  | author=Seifart KH, Wang L, Waldschmidt R, ''et al.'' |title=Purification of human transcription factor IIIA and its interaction with a chemically synthesized gene encoding human 5 S rRNA. |journal=J. Biol. Chem. |volume=264 |issue= 3 |pages= 1702-9 |year= 1989 |pmid= 2912980 |doi=  }}
+* {{cite journal | vauthors = Moorefield B, Roeder RG | title = Purification and characterization of human transcription factor IIIA | journal = The Journal of Biological Chemistry | volume = 269 | issue = 33 | pages = 20857–65 | date = Aug 1994 | pmid = 8063702 | doi =  }}
-*{{cite journal  | author=Drew PD, Nagle JW, Canning RD, ''et al.'' |title=Cloning and expression analysis of a human cDNA homologous to Xenopus TFIIIA. |journal=Gene |volume=159 |issue= 2 |pages= 215-8 |year= 1995 |pmid= 7622052 |doi=  }}
+* {{cite journal | vauthors = Fridell RA, Fischer U, Lührmann R, Meyer BE, Meinkoth JL, Malim MH, Cullen BR | title = Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 93 | issue = 7 | pages = 2936–40 | date = Apr 1996 | pmid = 8610146 | pmc = 39738 | doi = 10.1073/pnas.93.7.2936 }}
-*{{cite journal  | author=Arakawa H, Nagase H, Hayashi N, ''et al.'' |title=Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA. |journal=Cytogenet. Cell Genet. |volume=70 |issue= 3-4 |pages= 235-8 |year= 1995 |pmid= 7789179 |doi=  }}
+* {{cite journal | vauthors = Oettel S, Härtel F, Kober I, Iben S, Seifart KH | title = Human transcription factors IIIC2 , IIIC1 and a novel component IIIC0 fulfil different aspects of DNA binding to various pol III genes | journal = Nucleic Acids Research | volume = 25 | issue = 12 | pages = 2440–7 | date = Jun 1997 | pmid = 9171097 | pmc = 146769 | doi = 10.1093/nar/25.12.2440 }}
-*{{cite journal  | author=Moorefield B, Roeder RG |title=Purification and characterization of human transcription factor IIIA. |journal=J. Biol. Chem. |volume=269 |issue= 33 |pages= 20857-65 |year= 1994 |pmid= 8063702 |doi=  }}
+* {{cite journal | vauthors = Moreland RJ, Dresser ME, Rodgers JS, Roe BA, Conaway JW, Conaway RC, Hanas JS | title = Identification of a transcription factor IIIA-interacting protein | journal = Nucleic Acids Research | volume = 28 | issue = 9 | pages = 1986–93 | date = May 2000 | pmid = 10756201 | pmc = 103300 | doi = 10.1093/nar/28.9.1986 }}
-*{{cite journal  | author=Fridell RA, Fischer U, Lührmann R, ''et al.'' |title=Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 7 |pages= 2936-40 |year= 1996 |pmid= 8610146 |doi=  }}
+* {{cite journal | vauthors = Rao DS, Chang JC, Kumar PD, Mizukami I, Smithson GM, Bradley SV, Parlow AF, Ross TS | title = Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors | journal = Molecular and Cellular Biology | volume = 21 | issue = 22 | pages = 7796–806 | date = Nov 2001 | pmid = 11604514 | pmc = 99949 | doi = 10.1128/MCB.21.22.7796-7806.2001 }}
-*{{cite journal  | author=Oettel S, Härtel F, Kober I, ''et al.'' |title=Human transcription factors IIIC2 , IIIC1 and a novel component IIIC0 fulfil different aspects of DNA binding to various pol III genes. |journal=Nucleic Acids Res. |volume=25 |issue= 12 |pages= 2440-7 |year= 1997 |pmid= 9171097 |doi=  }}
+* {{cite journal | vauthors = Hanas JS, Hocker JR, Cheng YG, Lerner MR, Brackett DJ, Lightfoot SA, Hanas RJ, Madhusudhan KT, Moreland RJ | title = cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA | journal = Gene | volume = 282 | issue = 1-2 | pages = 43–52 | date = Jan 2002 | pmid = 11814676 | doi = 10.1016/S0378-1119(01)00796-X }}
-*{{cite journal  | author=Moreland RJ, Dresser ME, Rodgers JS, ''et al.'' |title=Identification of a transcription factor IIIA-interacting protein. |journal=Nucleic Acids Res. |volume=28 |issue= 9 |pages= 1986-93 |year= 2000 |pmid= 10756201 |doi=  }}
+* {{cite journal | vauthors = Weser S, Riemann J, Seifart KH, Meissner W | title = Assembly and isolation of intermediate steps of transcription complexes formed on the human 5S rRNA gene | journal = Nucleic Acids Research | volume = 31 | issue = 9 | pages = 2408–16 | date = May 2003 | pmid = 12711686 | pmc = 154231 | doi = 10.1093/nar/gkg345 }}
-*{{cite journal  | author=Rao DS, Chang JC, Kumar PD, ''et al.'' |title=Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors. |journal=Mol. Cell. Biol. |volume=21 |issue= 22 |pages= 7796-806 |year= 2001 |pmid= 11604514 |doi= 10.1128/MCB.21.22.7796-7806.2001 }}
+* {{cite journal | vauthors = Pellikainen JM, Ropponen KM, Kataja VV, Kellokoski JK, Eskelinen MJ, Kosma VM | title = Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis | journal = Clinical Cancer Research | volume = 10 | issue = 22 | pages = 7621–8 | date = Nov 2004 | pmid = 15569994 | doi = 10.1158/1078-0432.CCR-04-1061 }}
-*{{cite journal  | author=Hanas JS, Hocker JR, Cheng YG, ''et al.'' |title=cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA. |journal=Gene |volume=282 |issue= 1-2 |pages= 43-52 |year= 2002 |pmid= 11814676 |doi=  }}
+* {{cite journal | vauthors = Paing MM, Johnston CA, Siderovski DP, Trejo J | title = Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization | journal = Molecular and Cellular Biology | volume = 26 | issue = 8 | pages = 3231–42 | date = Apr 2006 | pmid = 16581796 | pmc = 1446942 | doi = 10.1128/MCB.26.8.3231-3242.2006 }}
-*{{cite journal  | author=Weser S, Riemann J, Seifart KH, Meissner W |title=Assembly and isolation of intermediate steps of transcription complexes formed on the human 5S rRNA gene. |journal=Nucleic Acids Res. |volume=31 |issue= 9 |pages= 2408-16 |year= 2003 |pmid= 12711686 |doi=  }}
+* {{cite journal | vauthors = Yamashita A, Takada T, Nemoto K, Yamamoto G, Torii R | title = Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage | journal = FEBS Letters | volume = 580 | issue = 17 | pages = 4121–5 | date = Jul 2006 | pmid = 16828750 | doi = 10.1016/j.febslet.2006.06.057 }}
-*{{cite journal  | author=Pellikainen JM, Ropponen KM, Kataja VV, ''et al.'' |title=Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis. |journal=Clin. Cancer Res. |volume=10 |issue= 22 |pages= 7621-8 |year= 2005 |pmid= 15569994 |doi= 10.1158/1078-0432.CCR-04-1061 }}
+* {{cite journal | vauthors = Schwartz B, Melnikova VO, Tellez C, Mourad-Zeidan A, Blehm K, Zhao YJ, McCarty M, Adam L, Bar-Eli M | title = Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo | journal = Oncogene | volume = 26 | issue = 28 | pages = 4049–58 | date = Jun 2007 | pmid = 17224907 | doi = 10.1038/sj.onc.1210193 }}
-*{{cite journal  | author=Paing MM, Johnston CA, Siderovski DP, Trejo J |title=Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. |journal=Mol. Cell. Biol. |volume=26 |issue= 8 |pages= 3231-42 |year= 2006 |pmid= 16581796 |doi= 10.1128/MCB.26.8.3231-3242.2006 }}
-*{{cite journal  | author=Yamashita A, Takada T, Nemoto K, ''et al.'' |title=Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage. |journal=FEBS Lett. |volume=580 |issue= 17 |pages= 4121-5 |year= 2006 |pmid= 16828750 |doi= 10.1016/j.febslet.2006.06.057 }}
-*{{cite journal  | author=Schwartz B, Melnikova VO, Tellez C, ''et al.'' |title=Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo. |journal=Oncogene |volume=26 |issue= 28 |pages= 4049-58 |year= 2007 |pmid= 17224907 |doi= 10.1038/sj.onc.1210193 }}
-*{{cite journal  | author=Hannay JA, Liu J, Zhu QS, ''et al.'' |title=Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation. |journal=Mol. Cancer Ther. |volume=6 |issue= 5 |pages= 1650-60 |year= 2007 |pmid= 17513613 |doi= 10.1158/1535-7163.MCT-06-0636 }}
-}}
-{{refend}}
 == External links ==
 * {{MeshName|GTF3A+protein,+human}}
+{{NLM content}}
+{{Transcription factors|g2}}
+[[Category:Transcription factors]]
 {{protein-stub}}
-{{NLM content}}
-{{Transcription factors}}
-[[Category:Transcription factors]]
-{{WikiDoc Sources}}

GTF3A: Difference between revisions

Latest revision as of 11:32, 9 January 2019

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