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'''HMG-box transcription factor 1''', also known as '''HBP1''', is a human [[protein]].<ref name="entrez">{{cite web | title = Entrez Gene: HBP1 HMG-box transcription factor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26959| accessdate = }}</ref> | |||
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'''HMG-box transcription factor 1''', also known as '''HBP1''', is a human [[ | |||
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==Interactions== | |||
HBP1 has been shown to [[Protein–protein interaction|interact]] with [[SIN3A]]<ref name=pmid15235594>{{cite journal |last=Swanson |first=Kurt A |authorlink= |author2=Knoepfler Paul S |author3=Huang Kai |author4=Kang Richard S |author5=Cowley Shaun M |author6=Laherty Carol D |author7=Eisenman Robert N |author8=Radhakrishnan Ishwar |date=Aug 2004 |title=HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations |journal=Nat. Struct. Mol. Biol. |volume=11 |issue=8 |pages=738–46 |publisher= |location = United States| issn = 1545-9993| pmid = 15235594 |doi = 10.1038/nsmb798 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[Retinoblastoma protein]].<ref name=pmid9178770>{{cite journal |last=Lavender |first=P |authorlink= |author2=Vandel L |author3=Bannister A J |author4=Kouzarides T |date=Jun 1997 |title=The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A |journal=Oncogene |volume=14 |issue=22 |pages=2721–8 |publisher= |location = ENGLAND| issn = 0950-9232| pmid = 9178770 |doi = 10.1038/sj.onc.1201243 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> | |||
==References== | ==References== | ||
{{reflist | {{reflist}} | ||
==Further reading== | ==Further reading== | ||
{{refbegin | 2}} | {{refbegin | 2}} | ||
{{PBB_Further_reading | {{PBB_Further_reading | ||
| citations = | | citations = | ||
*{{cite journal | *{{cite journal |vauthors=Tevosian SG, Shih HH, Mendelson KG, etal |title=HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family. |journal=Genes Dev. |volume=11 |issue= 3 |pages= 383–96 |year= 1997 |pmid= 9030690 |doi=10.1101/gad.11.3.383 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Lavender P, Vandel L, Bannister AJ, Kouzarides T |title=The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A. |journal=Oncogene |volume=14 |issue= 22 |pages= 2721–8 |year= 1997 |pmid= 9178770 |doi= 10.1038/sj.onc.1201243 }} | ||
*{{cite journal | *{{cite journal |vauthors=Zhuma T, Tyrrell R, Sekkali B, etal |title=Human HMG box transcription factor HBP1: a role in hCD2 LCR function |journal=EMBO J. |volume=18 |issue= 22 |pages= 6396–406 |year= 2000 |pmid= 10562551 |doi= 10.1093/emboj/18.22.6396 | pmc=1171702 }} | ||
*{{cite journal | *{{cite journal |vauthors=Lemercier C, Duncliffe K, Boibessot I, etal |title=Involvement of Retinoblastoma Protein and HBP1 in Histone H10 Gene Expression |journal=Mol. Cell. Biol. |volume=20 |issue= 18 |pages= 6627–37 |year= 2000 |pmid= 10958660 |doi=10.1128/MCB.20.18.6627-6637.2000 | pmc=86159 }} | ||
*{{cite journal | *{{cite journal |vauthors=Shih HH, Xiu M, Berasi SP, etal |title=HMG Box Transcriptional Repressor HBP1 Maintains a Proliferation Barrier in Differentiated Liver Tissue |journal=Mol. Cell. Biol. |volume=21 |issue= 17 |pages= 5723–32 |year= 2001 |pmid= 11486012 |doi=10.1128/MCB.21.17.5723-5732.2001 | pmc=87292 }} | ||
*{{cite journal | *{{cite journal |vauthors=Sampson EM, Haque ZK, Ku MC, etal |title=Negative regulation of the Wnt–β-catenin pathway by the transcriptional repressor HBP1 |journal=EMBO J. |volume=20 |issue= 16 |pages= 4500–11 |year= 2001 |pmid= 11500377 |doi= 10.1093/emboj/20.16.4500 | pmc=125566 }} | ||
*{{cite journal | *{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M }} | ||
*{{cite journal | *{{cite journal |vauthors=Hillier LW, Fulton RS, Fulton LA, etal |title=The DNA sequence of human chromosome 7 |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 |bibcode=2003Natur.424..157H }} | ||
*{{cite journal | *{{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }} | ||
*{{cite journal | | *{{cite journal |vauthors=de Chiara C, Kelly G, Frenkiel TA, Pastore A |title=Assignment of the 1H, 13C, and 15N resonances of the AXH domain of the transcription factor HBP1 |journal=J. Biomol. NMR |volume=28 |issue= 4 |pages= 411–2 |year= 2004 |pmid= 14872137 |doi= 10.1023/B:JNMR.0000015367.92295.0f }} | ||
*{{cite journal | | *{{cite journal |vauthors=Berasi SP, Xiu M, Yee AS, Paulson KE |title=HBP1 Repression of the p47phox Gene: Cell Cycle Regulation via the NADPH Oxidase |journal=Mol. Cell. Biol. |volume=24 |issue= 7 |pages= 3011–24 |year= 2004 |pmid= 15024088 |doi=10.1128/MCB.24.7.3011-3024.2004 | pmc=371097 }} | ||
*{{cite journal | *{{cite journal |vauthors=Colland F, Jacq X, Trouplin V, etal |title=Functional Proteomics Mapping of a Human Signaling Pathway |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 | pmc=442148 }} | ||
*{{cite journal | *{{cite journal |vauthors=Swanson KA, Knoepfler PS, Huang K, etal |title=HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations |journal=Nat. Struct. Mol. Biol. |volume=11 |issue= 8 |pages= 738–46 |year= 2004 |pmid= 15235594 |doi= 10.1038/nsmb798 }} | ||
*{{cite journal | *{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Yao CJ, Works K, Romagnoli PA, Austin GE |title=Effects of overexpression of HBP1 upon growth and differentiation of leukemic myeloid cells |journal=Leukemia |volume=19 |issue= 11 |pages= 1958–68 |year= 2005 |pmid= 16179914 |doi= 10.1038/sj.leu.2403918 }} | ||
*{{cite journal | *{{cite journal |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein–protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R }} | ||
*{{cite journal | *{{cite journal |vauthors=Sekkali B, Szabat E, Ktistaki E, etal |title=Human high mobility group box transcription factor 1 affects thymocyte development and transgene variegation |journal=J. Immunol. |volume=175 |issue= 8 |pages= 5203–12 |year= 2005 |pmid= 16210625 |doi= 10.4049/jimmunol.175.8.5203}} | ||
*{{cite journal | *{{cite journal |vauthors=Kim J, Zhang X, Rieger-Christ KM, etal |title=Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1 |journal=J. Biol. Chem. |volume=281 |issue= 16 |pages= 10865–75 |year= 2006 |pmid= 16495219 |doi= 10.1074/jbc.M513378200 }} | ||
*{{cite journal | *{{cite journal |vauthors=Lim J, Hao T, Shaw C, etal |title=A protein–protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 }} | ||
*{{cite journal | *{{cite journal |vauthors=Zhang X, Kim J, Ruthazer R, etal |title=The HBP1 Transcriptional Repressor Participates in RAS-Induced Premature Senescence |journal=Mol. Cell. Biol. |volume=26 |issue= 22 |pages= 8252–66 |year= 2007 |pmid= 16966377 |doi= 10.1128/MCB.00604-06 | pmc=1636767 }} | ||
}} | }} | ||
{{refend}} | {{refend}} | ||
{{PDB Gallery|geneid=26959}} | |||
== External links == | == External links == | ||
* {{MeshName|HBP1+protein,+human}} | * {{MeshName|HBP1+protein,+human}} | ||
{{ | {{Transcription factors|g0}} | ||
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[[Category:Transcription factors]] | [[Category:Transcription factors]] | ||
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{{gene-7-stub}} |
Latest revision as of 19:40, 23 June 2018
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External IDs | GeneCards: [1] | ||||||
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Species | Human | Mouse | |||||
Entrez |
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Ensembl |
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UniProt |
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RefSeq (mRNA) |
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RefSeq (protein) |
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Location (UCSC) | n/a | n/a | |||||
PubMed search | n/a | n/a | |||||
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HMG-box transcription factor 1, also known as HBP1, is a human protein.[1]
Interactions
HBP1 has been shown to interact with SIN3A[2] and Retinoblastoma protein.[3]
References
- ↑ "Entrez Gene: HBP1 HMG-box transcription factor 1".
- ↑ Swanson, Kurt A; Knoepfler Paul S; Huang Kai; Kang Richard S; Cowley Shaun M; Laherty Carol D; Eisenman Robert N; Radhakrishnan Ishwar (Aug 2004). "HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations". Nat. Struct. Mol. Biol. United States. 11 (8): 738–46. doi:10.1038/nsmb798. ISSN 1545-9993. PMID 15235594.
- ↑ Lavender, P; Vandel L; Bannister A J; Kouzarides T (Jun 1997). "The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A". Oncogene. ENGLAND. 14 (22): 2721–8. doi:10.1038/sj.onc.1201243. ISSN 0950-9232. PMID 9178770.
Further reading
- Tevosian SG, Shih HH, Mendelson KG, et al. (1997). "HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family". Genes Dev. 11 (3): 383–96. doi:10.1101/gad.11.3.383. PMID 9030690.
- Lavender P, Vandel L, Bannister AJ, Kouzarides T (1997). "The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A". Oncogene. 14 (22): 2721–8. doi:10.1038/sj.onc.1201243. PMID 9178770.
- Zhuma T, Tyrrell R, Sekkali B, et al. (2000). "Human HMG box transcription factor HBP1: a role in hCD2 LCR function". EMBO J. 18 (22): 6396–406. doi:10.1093/emboj/18.22.6396. PMC 1171702. PMID 10562551.
- Lemercier C, Duncliffe K, Boibessot I, et al. (2000). "Involvement of Retinoblastoma Protein and HBP1 in Histone H10 Gene Expression". Mol. Cell. Biol. 20 (18): 6627–37. doi:10.1128/MCB.20.18.6627-6637.2000. PMC 86159. PMID 10958660.
- Shih HH, Xiu M, Berasi SP, et al. (2001). "HMG Box Transcriptional Repressor HBP1 Maintains a Proliferation Barrier in Differentiated Liver Tissue". Mol. Cell. Biol. 21 (17): 5723–32. doi:10.1128/MCB.21.17.5723-5732.2001. PMC 87292. PMID 11486012.
- Sampson EM, Haque ZK, Ku MC, et al. (2001). "Negative regulation of the Wnt–β-catenin pathway by the transcriptional repressor HBP1". EMBO J. 20 (16): 4500–11. doi:10.1093/emboj/20.16.4500. PMC 125566. PMID 11500377.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi:10.1038/nature01782. PMID 12853948.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- de Chiara C, Kelly G, Frenkiel TA, Pastore A (2004). "Assignment of the 1H, 13C, and 15N resonances of the AXH domain of the transcription factor HBP1". J. Biomol. NMR. 28 (4): 411–2. doi:10.1023/B:JNMR.0000015367.92295.0f. PMID 14872137.
- Berasi SP, Xiu M, Yee AS, Paulson KE (2004). "HBP1 Repression of the p47phox Gene: Cell Cycle Regulation via the NADPH Oxidase". Mol. Cell. Biol. 24 (7): 3011–24. doi:10.1128/MCB.24.7.3011-3024.2004. PMC 371097. PMID 15024088.
- Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
- Swanson KA, Knoepfler PS, Huang K, et al. (2004). "HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations". Nat. Struct. Mol. Biol. 11 (8): 738–46. doi:10.1038/nsmb798. PMID 15235594.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Yao CJ, Works K, Romagnoli PA, Austin GE (2005). "Effects of overexpression of HBP1 upon growth and differentiation of leukemic myeloid cells". Leukemia. 19 (11): 1958–68. doi:10.1038/sj.leu.2403918. PMID 16179914.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein–protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514.
- Sekkali B, Szabat E, Ktistaki E, et al. (2005). "Human high mobility group box transcription factor 1 affects thymocyte development and transgene variegation". J. Immunol. 175 (8): 5203–12. doi:10.4049/jimmunol.175.8.5203. PMID 16210625.
- Kim J, Zhang X, Rieger-Christ KM, et al. (2006). "Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1". J. Biol. Chem. 281 (16): 10865–75. doi:10.1074/jbc.M513378200. PMID 16495219.
- Lim J, Hao T, Shaw C, et al. (2006). "A protein–protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
- Zhang X, Kim J, Ruthazer R, et al. (2007). "The HBP1 Transcriptional Repressor Participates in RAS-Induced Premature Senescence". Mol. Cell. Biol. 26 (22): 8252–66. doi:10.1128/MCB.00604-06. PMC 1636767. PMID 16966377.
External links
- HBP1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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