POU4F2: Difference between revisions

Jump to navigation Jump to search
m (task, replaced: International Journal of Cancer. Journal International Du Cancer → International Journal of Cancer using AWB)
m (Open access bot: add pmc identifier to citation with #oabot.)
Line 26: Line 26:
* {{cite journal | vauthors = de Melo J, Qiu X, Du G, Cristante L, Eisenstat DD | title = Dlx1, Dlx2, Pax6, Brn3b, and Chx10 homeobox gene expression defines the retinal ganglion and inner nuclear layers of the developing and adult mouse retina | journal = The Journal of Comparative Neurology | volume = 461 | issue = 2 | pages = 187–204 | date = Jun 2003 | pmid = 12724837 | doi = 10.1002/cne.10674 }}
* {{cite journal | vauthors = de Melo J, Qiu X, Du G, Cristante L, Eisenstat DD | title = Dlx1, Dlx2, Pax6, Brn3b, and Chx10 homeobox gene expression defines the retinal ganglion and inner nuclear layers of the developing and adult mouse retina | journal = The Journal of Comparative Neurology | volume = 461 | issue = 2 | pages = 187–204 | date = Jun 2003 | pmid = 12724837 | doi = 10.1002/cne.10674 }}
* {{cite journal | vauthors = Samady L, Dennis J, Budhram-Mahadeo V, Latchman DS | title = Activation of CDK4 gene expression in human breast cancer cells by the Brn-3b POU family transcription factor | journal = Cancer Biology & Therapy | volume = 3 | issue = 3 | pages = 317–23 | date = Mar 2004 | pmid = 14726699 | doi = 10.4161/cbt.3.3.698 }}
* {{cite journal | vauthors = Samady L, Dennis J, Budhram-Mahadeo V, Latchman DS | title = Activation of CDK4 gene expression in human breast cancer cells by the Brn-3b POU family transcription factor | journal = Cancer Biology & Therapy | volume = 3 | issue = 3 | pages = 317–23 | date = Mar 2004 | pmid = 14726699 | doi = 10.4161/cbt.3.3.698 }}
* {{cite journal | vauthors = Irshad S, Pedley RB, Anderson J, Latchman DS, Budhram-Mahadeo V | title = The Brn-3b transcription factor regulates the growth, behavior, and invasiveness of human neuroblastoma cells in vitro and in vivo | journal = The Journal of Biological Chemistry | volume = 279 | issue = 20 | pages = 21617–27 | date = May 2004 | pmid = 14970234 | doi = 10.1074/jbc.M312506200 }}
* {{cite journal | vauthors = Irshad S, Pedley RB, Anderson J, Latchman DS, Budhram-Mahadeo V | title = The Brn-3b transcription factor regulates the growth, behavior, and invasiveness of human neuroblastoma cells in vitro and in vivo | journal = The Journal of Biological Chemistry | volume = 279 | issue = 20 | pages = 21617–27 | date = May 2004 | pmid = 14970234 | doi = 10.1074/jbc.M312506200 | pmc = 4294515 }}
* {{cite journal | vauthors = Lee SA, Ndisang D, Patel C, Dennis JH, Faulkes DJ, D'Arrigo C, Samady L, Farooqui-Kabir S, Heads RJ, Latchman DS, Budhram-Mahadeo VS | title = Expression of the Brn-3b transcription factor correlates with expression of HSP-27 in breast cancer biopsies and is required for maximal activation of the HSP-27 promoter | journal = Cancer Research | volume = 65 | issue = 8 | pages = 3072–80 | date = Apr 2005 | pmid = 15833836 | doi = 10.1158/0008-5472.CAN-04-2865 }}
* {{cite journal | vauthors = Lee SA, Ndisang D, Patel C, Dennis JH, Faulkes DJ, D'Arrigo C, Samady L, Farooqui-Kabir S, Heads RJ, Latchman DS, Budhram-Mahadeo VS | title = Expression of the Brn-3b transcription factor correlates with expression of HSP-27 in breast cancer biopsies and is required for maximal activation of the HSP-27 promoter | journal = Cancer Research | volume = 65 | issue = 8 | pages = 3072–80 | date = Apr 2005 | pmid = 15833836 | doi = 10.1158/0008-5472.CAN-04-2865 }}
* {{cite journal | vauthors = Weishaupt JH, Klöcker N, Bähr M | title = Axotomy-induced early down-regulation of POU-IV class transcription factors Brn-3a and Brn-3b in retinal ganglion cells | journal = Journal of Molecular Neuroscience | volume = 26 | issue = 1 | pages = 17–25 | year = 2005 | pmid = 15968082 | doi = 10.1385/JMN:26:1:017 }}
* {{cite journal | vauthors = Weishaupt JH, Klöcker N, Bähr M | title = Axotomy-induced early down-regulation of POU-IV class transcription factors Brn-3a and Brn-3b in retinal ganglion cells | journal = Journal of Molecular Neuroscience | volume = 26 | issue = 1 | pages = 17–25 | year = 2005 | pmid = 15968082 | doi = 10.1385/JMN:26:1:017 }}

Revision as of 19:13, 15 May 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

POU domain, class 4, transcription factor 2 is a protein that in humans is encoded by the POU4F2 gene.[1][2]

Function

POU4F2 is a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F2 is found in human retina exclusively within a subpopulation of ganglion cells where it may play a role in determining or maintaining the identities of a small subset of visual system neurons.[supplied by OMIM][2]

Interactions

POU4F2 has been shown to interact with Estrogen receptor alpha.[3]

See also

References

  1. Ring CJ, Latchman DS (Jun 1993). "The human Brn-3b POU transcription factor shows only limited homology to the Brn-3a/RDC-1 factor outside the conserved POU domain". Nucleic Acids Research. 21 (12): 2946. doi:10.1093/nar/21.12.2946. PMC 309696. PMID 8332509.
  2. 2.0 2.1 "Entrez Gene: POU4F2 POU domain, class 4, transcription factor 2".
  3. Budhram-Mahadeo V, Parker M, Latchman DS (Feb 1998). "POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element". Molecular and Cellular Biology. 18 (2): 1029–41. doi:10.1128/mcb.18.2.1029. PMC 108815. PMID 9448000.

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.