CBX3: Difference between revisions

VALUE_ERROR (nil)
Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

VisualWikitext

Revision as of 09:14, 30 August 2017

Chromobox protein homolog 3 is a protein that is encoded by the CBX3 gene in humans.^[1]^[2]

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.^[2]

Interactions

CBX3 has been shown to interact with PIM1,^[3] Ki-67,^[4] Lamin B receptor,^[5] CBX5^[6] and CBX1.^[6]

References

↑ Ye Q, Worman HJ (August 1996). "Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1". J Biol Chem. 271 (25): 14653–6. doi:10.1074/jbc.271.25.14653. PMID 8663349.
↑ ^2.0 ^2.1 "Entrez Gene: CBX3 chromobox homolog 3 (HP1 gamma homolog, Drosophila)".
↑ Koike, N; Maita H; Taira T; Ariga H; Iguchi-Ariga S M (February 2000). "Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1)". FEBS Lett. NETHERLANDS. 467 (1): 17–21. doi:10.1016/S0014-5793(00)01105-4. ISSN 0014-5793. PMID 10664448.
↑ Kametaka, Ai; Takagi Masatoshi; Hayakawa Tomohiro; Haraguchi Tokuko; Hiraoka Yasushi; Yoneda Yoshihiro (December 2002). "Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins". Genes Cells. England. 7 (12): 1231–42. doi:10.1046/j.1365-2443.2002.00596.x. ISSN 1356-9597. PMID 12485163.
↑ Ye, Q; Worman H J (June 1996). "Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1". J. Biol. Chem. UNITED STATES. 271 (25): 14653–6. doi:10.1074/jbc.271.25.14653. ISSN 0021-9258. PMID 8663349.
↑ ^6.0 ^6.1 Nielsen, A L; Oulad-Abdelghani M; Ortiz J A; Remboutsika E; Chambon P; Losson R (April 2001). "Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins". Mol. Cell. United States. 7 (4): 729–39. doi:10.1016/S1097-2765(01)00218-0. ISSN 1097-2765. PMID 11336697.

Ye Q, Callebaut I, Pezhman A, et al. (1997). "Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR". J. Biol. Chem. 272 (23): 14983–9. doi:10.1074/jbc.272.23.14983. PMID 9169472.
Lessard J, Baban S, Sauvageau G (1998). "Stage-specific expression of polycomb group genes in human bone marrow cells". Blood. 91 (4): 1216–24. PMID 9454751.
Seeler JS, Marchio A, Sitterlin D, et al. (1998). "Interaction of SP100 with HP1 proteins: A link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment". Proc. Natl. Acad. Sci. U.S.A. 95 (13): 7316–21. doi:10.1073/pnas.95.13.7316. PMC 22602. PMID 9636146.
Lehming N, Le Saux A, Schüller J, Ptashne M (1998). "Chromatin components as part of a putative transcriptional repressing complex". Proc. Natl. Acad. Sci. U.S.A. 95 (13): 7322–6. doi:10.1073/pnas.95.13.7322. PMC 22604. PMID 9636147.
Ainsztein AM, Kandels-Lewis SE, Mackay AM, Earnshaw WC (1999). "INCENP Centromere and Spindle Targeting: Identification of Essential Conserved Motifs and Involvement of Heterochromatin Protein HP1". J. Cell Biol. 143 (7): 1763–74. doi:10.1083/jcb.143.7.1763. PMC 2175214. PMID 9864353.
Ryan RF, Schultz DC, Ayyanathan K, et al. (1999). "KAP-1 Corepressor Protein Interacts and Colocalizes with Heterochromatic and Euchromatic HP1 Proteins: a Potential Role for Krüppel-Associated Box–Zinc Finger Proteins in Heterochromatin-Mediated Gene Silencing". Mol. Cell. Biol. 19 (6): 4366–78. doi:10.1128/mcb.19.6.4366. PMC 104396. PMID 10330177.
Minc E, Allory Y, Worman HJ, et al. (1999). "Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells". Chromosoma. 108 (4): 220–34. doi:10.1007/s004120050372. PMID 10460410.
Nielsen AL, Ortiz JA, You J, et al. (2000). "Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family". EMBO J. 18 (22): 6385–95. doi:10.1093/emboj/18.22.6385. PMC 1171701. PMID 10562550.
Koike N, Maita H, Taira T, et al. (2000). "Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1)". FEBS Lett. 467 (1): 17–21. doi:10.1016/S0014-5793(00)01105-4. PMID 10664448.
Minc E, Courvalin JC, Buendia B (2001). "HP1gamma associates with euchromatin and heterochromatin in mammalian nuclei and chromosomes". Cytogenet. Cell Genet. 90 (3–4): 279–84. doi:10.1159/000056789. PMID 11124534.
Lachner M, O'Carroll D, Rea S, et al. (2001). "Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins". Nature. 410 (6824): 116–20. doi:10.1038/35065132. PMID 11242053.
Nielsen AL, Oulad-Abdelghani M, Ortiz JA, et al. (2001). "Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins". Mol. Cell. 7 (4): 729–39. doi:10.1016/S1097-2765(01)00218-0. PMID 11336697.
Scholzen T, Endl E, Wohlenberg C, et al. (2002). "The Ki-67 protein interacts with members of the heterochromatin protein 1 (HP1) family: a potential role in the regulation of higher-order chromatin structure". J. Pathol. 196 (2): 135–44. doi:10.1002/path.1016. PMID 11793364.
Vassallo MF, Tanese N (2002). "Isoform-specific interaction of HP1 with human TAFII130". Proc. Natl. Acad. Sci. U.S.A. 99 (9): 5919–24. doi:10.1073/pnas.092025499. PMC 122877. PMID 11959914.
Ogawa H, Ishiguro K, Gaubatz S, et al. (2002). "A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells". Science. 296 (5570): 1132–6. doi:10.1126/science.1069861. PMID 12004135.
Hwang KK, Worman HJ (2002). "Gene regulation by human orthologs of Drosophila heterochromatin protein 1". Biochem. Biophys. Res. Commun. 293 (4): 1217–22. doi:10.1016/S0006-291X(02)00377-7. PMID 12054505.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Kametaka A, Takagi M, Hayakawa T, et al. (2003). "Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins". Genes Cells. 7 (12): 1231–42. doi:10.1046/j.1365-2443.2002.00596.x. PMID 12485163.
Cheutin T, McNairn AJ, Jenuwein T, et al. (2003). "Maintenance of stable heterochromatin domains by dynamic HP1 binding". Science. 299 (5607): 721–5. doi:10.1126/science.1078572. PMID 12560555.

External links

CBX3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
Human CBX3 genome location and CBX3 gene details page in the UCSC Genome Browser.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[pmid8663349-1] Ye Q, Worman HJ (August 1996). "Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1". J Biol Chem. 271 (25): 14653–6. doi:10.1074/jbc.271.25.14653. PMID 8663349.

[entrez-2] 2.0 ^2.1 "Entrez Gene: CBX3 chromobox homolog 3 (HP1 gamma homolog, Drosophila)".

[pmid10664448-3] Koike, N; Maita H; Taira T; Ariga H; Iguchi-Ariga S M (February 2000). "Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1)". FEBS Lett. NETHERLANDS. 467 (1): 17–21. doi:10.1016/S0014-5793(00)01105-4. ISSN 0014-5793. PMID 10664448.

[pmid12485163-4] Kametaka, Ai; Takagi Masatoshi; Hayakawa Tomohiro; Haraguchi Tokuko; Hiraoka Yasushi; Yoneda Yoshihiro (December 2002). "Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins". Genes Cells. England. 7 (12): 1231–42. doi:10.1046/j.1365-2443.2002.00596.x. ISSN 1356-9597. PMID 12485163.

[autogenerated1-5] Ye, Q; Worman H J (June 1996). "Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1". J. Biol. Chem. UNITED STATES. 271 (25): 14653–6. doi:10.1074/jbc.271.25.14653. ISSN 0021-9258. PMID 8663349.

[pmid11336697-6] 6.0 ^6.1 Nielsen, A L; Oulad-Abdelghani M; Ortiz J A; Remboutsika E; Chambon P; Losson R (April 2001). "Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins". Mol. Cell. United States. 7 (4): 729–39. doi:10.1016/S1097-2765(01)00218-0. ISSN 1097-2765. PMID 11336697.

[1]

[2]

[3]

[4]

[5]

[6]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Chromobox protein homolog 3''' is a [[protein]] that is encoded by the ''CBX3'' [[gene]] in humans.<ref name="pmid8663349">{{cite journal | vauthors = Ye Q, Worman HJ | title = Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1 | journal = J Biol Chem | volume = 271 | issue = 25 | pages = 14653–6 |date=August 1996 | pmid = 8663349 | pmc =  | doi =10.1074/jbc.271.25.14653  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CBX3 chromobox homolog 3 (HP1 gamma homolog, Drosophila)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11335| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Chromobox homolog 3 (HP1 gamma homolog, Drosophila)
- | HGNCid = 1553
- | Symbol = CBX3
- | AltSymbols =; HECH; HP1-GAMMA; HP1Hs-gamma
- | OMIM = 604477
- | ECnumber =
- | Homologene = 40583
- | MGIid = 108515
- | GeneAtlas_image1 = PBB_GE_CBX3_200037_s_at_tn.png
- | Function = {{GNF_GO|id=GO:0003682 |text = chromatin binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
- | Component = {{GNF_GO|id=GO:0000785 |text = chromatin}} {{GNF_GO|id=GO:0005634 |text = nucleus}}
- | Process = {{GNF_GO|id=GO:0006333 |text = chromatin assembly or disassembly}} {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0016568 |text = chromatin modification}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 11335
-    | Hs_Ensembl =
-    | Hs_RefseqProtein = NP_009207
-    | Hs_RefseqmRNA = NM_007276
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr =
-    | Hs_GenLoc_start =
-    | Hs_GenLoc_end =
-    | Hs_Uniprot =
-    | Mm_EntrezGene = 12417
-    | Mm_Ensembl =
-    | Mm_RefseqmRNA = NM_001037798
-    | Mm_RefseqProtein = NP_001032887
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr =
-    | Mm_GenLoc_start =
-    | Mm_GenLoc_end =
-    | Mm_Uniprot =
-  }}
-}}
-'''Chromobox homolog 3 (HP1 gamma homolog, Drosophila)''', also known as '''CBX3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CBX3 chromobox homolog 3 (HP1 gamma homolog, Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11335| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
 {{PBB_Summary
 | section_title =
-| summary_text = At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.<ref name="entrez">{{cite web | title = Entrez Gene: CBX3 chromobox homolog 3 (HP1 gamma homolog, Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11335| accessdate = }}</ref>
+| summary_text = At the nuclear envelope, the [[nuclear lamina]] and [[heterochromatin]] are adjacent to the inner [[nuclear membrane]]. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.<ref name="entrez" />
 }}
+==Interactions==
+CBX3 has been shown to [[Protein-protein interaction|interact]] with [[PIM1]],<ref name=pmid10664448>{{cite journal |last=Koike |first=N |author2=Maita H|author3=Taira T|author4=Ariga H|author5=Iguchi-Ariga S M |date=February 2000  |title=Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1) |journal=FEBS Lett. |volume=467 |issue=1 |pages=17–21 |publisher= |location = NETHERLANDS| issn = 0014-5793| pmid = 10664448 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1016/S0014-5793(00)01105-4 }}</ref> [[Ki-67 (protein)|Ki-67]],<ref name=pmid12485163>{{cite journal |last=Kametaka |first=Ai |author2=Takagi Masatoshi |author3=Hayakawa Tomohiro |author4=Haraguchi Tokuko |author5=Hiraoka Yasushi |author6=Yoneda Yoshihiro  |date=December 2002  |title=Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins |journal=Genes Cells |volume=7 |issue=12 |pages=1231–42 |publisher= |location = England| issn = 1356-9597| pmid = 12485163 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1046/j.1365-2443.2002.00596.x }}</ref> [[Lamin B receptor]],<ref name=autogenerated1>{{cite journal |last=Ye |first=Q |author2=Worman H J |date=June 1996  |title=Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1 |journal=J. Biol. Chem. |volume=271 |issue=25 |pages=14653–6 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 8663349 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1074/jbc.271.25.14653 }}</ref> [[CBX5 (gene)|CBX5]]<ref name=pmid11336697>{{cite journal |last=Nielsen |first=A L |author2=Oulad-Abdelghani M|author3=Ortiz J A|author4=Remboutsika E|author5=Chambon P|author6=Losson R |date=April 2001  |title=Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins |journal=Mol. Cell |volume=7 |issue=4 |pages=729–39 |publisher= |location = United States| issn = 1097-2765| pmid = 11336697 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1016/S1097-2765(01)00218-0 }}</ref> and [[CBX1]].<ref name=pmid11336697/>
 ==See also==
@@ Line 58: / Line 15: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Ye Q, Worman HJ |title=Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1. |journal=J. Biol. Chem. |volume=271 |issue= 25 |pages= 14653-6 |year= 1996 |pmid= 8663349 |doi=  }}
+*{{cite journal  | vauthors=Ye Q, Callebaut I, Pezhman A |title=Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR |journal=J. Biol. Chem. |volume=272 |issue= 23 |pages= 14983–9 |year= 1997 |pmid= 9169472 |doi=10.1074/jbc.272.23.14983  |display-authors=etal}}
-*{{cite journal  | author=Ye Q, Callebaut I, Pezhman A, ''et al.'' |title=Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR. |journal=J. Biol. Chem. |volume=272 |issue= 23 |pages= 14983-9 |year= 1997 |pmid= 9169472 |doi=  }}
+*{{cite journal  | vauthors=Lessard J, Baban S, Sauvageau G |title=Stage-specific expression of polycomb group genes in human bone marrow cells |journal=Blood |volume=91 |issue= 4 |pages= 1216–24 |year= 1998 |pmid= 9454751 |doi=  }}
-*{{cite journal  | author=Lessard J, Baban S, Sauvageau G |title=Stage-specific expression of polycomb group genes in human bone marrow cells. |journal=Blood |volume=91 |issue= 4 |pages= 1216-24 |year= 1998 |pmid= 9454751 |doi=  }}
+*{{cite journal  | vauthors=Seeler JS, Marchio A, Sitterlin D |title=Interaction of SP100 with HP1 proteins: A link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 13 |pages= 7316–21 |year= 1998 |pmid= 9636146 |doi=10.1073/pnas.95.13.7316  | pmc=22602  |display-authors=etal}}
-*{{cite journal  | author=Seeler JS, Marchio A, Sitterlin D, ''et al.'' |title=Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 13 |pages= 7316-21 |year= 1998 |pmid= 9636146 |doi=  }}
+*{{cite journal  | vauthors=Lehming N, Le Saux A, Schüller J, Ptashne M |title=Chromatin components as part of a putative transcriptional repressing complex |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 13 |pages= 7322–6 |year= 1998 |pmid= 9636147 |doi=10.1073/pnas.95.13.7322  | pmc=22604  }}
-*{{cite journal  | author=Lehming N, Le Saux A, Schüller J, Ptashne M |title=Chromatin components as part of a putative transcriptional repressing complex. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 13 |pages= 7322-6 |year= 1998 |pmid= 9636147 |doi=  }}
+*{{cite journal  | vauthors=Ainsztein AM, Kandels-Lewis SE, Mackay AM, Earnshaw WC |title=INCENP Centromere and Spindle Targeting: Identification of Essential Conserved Motifs and Involvement of Heterochromatin Protein HP1 |journal=J. Cell Biol. |volume=143 |issue= 7 |pages= 1763–74 |year= 1999 |pmid= 9864353 |doi=10.1083/jcb.143.7.1763  | pmc=2175214  }}
-*{{cite journal  | author=Ainsztein AM, Kandels-Lewis SE, Mackay AM, Earnshaw WC |title=INCENP centromere and spindle targeting: identification of essential conserved motifs and involvement of heterochromatin protein HP1. |journal=J. Cell Biol. |volume=143 |issue= 7 |pages= 1763-74 |year= 1999 |pmid= 9864353 |doi=  }}
+*{{cite journal  | vauthors=Ryan RF, Schultz DC, Ayyanathan K |title=KAP-1 Corepressor Protein Interacts and Colocalizes with Heterochromatic and Euchromatic HP1 Proteins: a Potential Role for Krüppel-Associated Box–Zinc Finger Proteins in Heterochromatin-Mediated Gene Silencing |journal=Mol. Cell. Biol. |volume=19 |issue= 6 |pages= 4366–78 |year= 1999 |pmid= 10330177 |doi=  10.1128/mcb.19.6.4366| pmc=104396  |display-authors=etal}}
-*{{cite journal  | author=Ryan RF, Schultz DC, Ayyanathan K, ''et al.'' |title=KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing. |journal=Mol. Cell. Biol. |volume=19 |issue= 6 |pages= 4366-78 |year= 1999 |pmid= 10330177 |doi=  }}
+*{{cite journal  | vauthors=Minc E, Allory Y, Worman HJ |title=Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells |journal=Chromosoma |volume=108 |issue= 4 |pages= 220–34 |year= 1999 |pmid= 10460410 |doi=10.1007/s004120050372  |display-authors=etal}}
-*{{cite journal  | author=Minc E, Allory Y, Worman HJ, ''et al.'' |title=Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells. |journal=Chromosoma |volume=108 |issue= 4 |pages= 220-34 |year= 1999 |pmid= 10460410 |doi=  }}
+*{{cite journal  | vauthors=Nielsen AL, Ortiz JA, You J |title=Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family |journal=EMBO J. |volume=18 |issue= 22 |pages= 6385–95 |year= 2000 |pmid= 10562550 |doi= 10.1093/emboj/18.22.6385  | pmc=1171701 |display-authors=etal}}
-*{{cite journal  | author=Nielsen AL, Ortiz JA, You J, ''et al.'' |title=Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family. |journal=EMBO J. |volume=18 |issue= 22 |pages= 6385-95 |year= 2000 |pmid= 10562550 |doi= 10.1093/emboj/18.22.6385 }}
+*{{cite journal  | vauthors=Koike N, Maita H, Taira T |title=Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1) |journal=FEBS Lett. |volume=467 |issue= 1 |pages= 17–21 |year= 2000 |pmid= 10664448 |doi=10.1016/S0014-5793(00)01105-4  |display-authors=etal}}
-*{{cite journal  | author=Koike N, Maita H, Taira T, ''et al.'' |title=Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1). |journal=FEBS Lett. |volume=467 |issue= 1 |pages= 17-21 |year= 2000 |pmid= 10664448 |doi=  }}
+*{{cite journal  | vauthors=Minc E, Courvalin JC, Buendia B |title=HP1gamma associates with euchromatin and heterochromatin in mammalian nuclei and chromosomes |journal=Cytogenet. Cell Genet. |volume=90 |issue= 3–4 |pages= 279–84 |year= 2001 |pmid= 11124534 |doi=10.1159/000056789  }}
-*{{cite journal  | author=Minc E, Courvalin JC, Buendia B |title=HP1gamma associates with euchromatin and heterochromatin in mammalian nuclei and chromosomes. |journal=Cytogenet. Cell Genet. |volume=90 |issue= 3-4 |pages= 279-84 |year= 2001 |pmid= 11124534 |doi=  }}
+*{{cite journal  | vauthors=Lachner M, O'Carroll D, Rea S |title=Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins |journal=Nature |volume=410 |issue= 6824 |pages= 116–20 |year= 2001 |pmid= 11242053 |doi= 10.1038/35065132 |display-authors=etal}}
-*{{cite journal  | author=Lachner M, O'Carroll D, Rea S, ''et al.'' |title=Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. |journal=Nature |volume=410 |issue= 6824 |pages= 116-20 |year= 2001 |pmid= 11242053 |doi= 10.1038/35065132 }}
+*{{cite journal  | vauthors=Nielsen AL, Oulad-Abdelghani M, Ortiz JA |title=Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins |journal=Mol. Cell |volume=7 |issue= 4 |pages= 729–39 |year= 2001 |pmid= 11336697 |doi=10.1016/S1097-2765(01)00218-0  |display-authors=etal}}
-*{{cite journal  | author=Nielsen AL, Oulad-Abdelghani M, Ortiz JA, ''et al.'' |title=Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins. |journal=Mol. Cell |volume=7 |issue= 4 |pages= 729-39 |year= 2001 |pmid= 11336697 |doi=  }}
+*{{cite journal  | vauthors=Scholzen T, Endl E, Wohlenberg C |title=The Ki-67 protein interacts with members of the heterochromatin protein 1 (HP1) family: a potential role in the regulation of higher-order chromatin structure |journal=J. Pathol. |volume=196 |issue= 2 |pages= 135–44 |year= 2002 |pmid= 11793364 |doi= 10.1002/path.1016 |display-authors=etal}}
-*{{cite journal  | author=Scholzen T, Endl E, Wohlenberg C, ''et al.'' |title=The Ki-67 protein interacts with members of the heterochromatin protein 1 (HP1) family: a potential role in the regulation of higher-order chromatin structure. |journal=J. Pathol. |volume=196 |issue= 2 |pages= 135-44 |year= 2002 |pmid= 11793364 |doi= 10.1002/path.1016 }}
+*{{cite journal  | vauthors=Vassallo MF, Tanese N |title=Isoform-specific interaction of HP1 with human TAFII130 |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 9 |pages= 5919–24 |year= 2002 |pmid= 11959914 |doi= 10.1073/pnas.092025499  | pmc=122877 }}
-*{{cite journal  | author=Vassallo MF, Tanese N |title=Isoform-specific interaction of HP1 with human TAFII130. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 9 |pages= 5919-24 |year= 2002 |pmid= 11959914 |doi= 10.1073/pnas.092025499 }}
+*{{cite journal  | vauthors=Ogawa H, Ishiguro K, Gaubatz S |title=A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells |journal=Science |volume=296 |issue= 5570 |pages= 1132–6 |year= 2002 |pmid= 12004135 |doi= 10.1126/science.1069861 |display-authors=etal}}
-*{{cite journal  | author=Ogawa H, Ishiguro K, Gaubatz S, ''et al.'' |title=A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells. |journal=Science |volume=296 |issue= 5570 |pages= 1132-6 |year= 2002 |pmid= 12004135 |doi= 10.1126/science.1069861 }}
+*{{cite journal  | vauthors=Hwang KK, Worman HJ |title=Gene regulation by human orthologs of Drosophila heterochromatin protein 1 |journal=Biochem. Biophys. Res. Commun. |volume=293 |issue= 4 |pages= 1217–22 |year= 2002 |pmid= 12054505 |doi= 10.1016/S0006-291X(02)00377-7 }}
-*{{cite journal  | author=Hwang KK, Worman HJ |title=Gene regulation by human orthologs of Drosophila heterochromatin protein 1. |journal=Biochem. Biophys. Res. Commun. |volume=293 |issue= 4 |pages= 1217-22 |year= 2002 |pmid= 12054505 |doi= 10.1016/S0006-291X(02)00377-7 }}
+*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal}}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | vauthors=Kametaka A, Takagi M, Hayakawa T |title=Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins |journal=Genes Cells |volume=7 |issue= 12 |pages= 1231–42 |year= 2003 |pmid= 12485163 |doi=10.1046/j.1365-2443.2002.00596.x  |display-authors=etal}}
-*{{cite journal  | author=Kametaka A, Takagi M, Hayakawa T, ''et al.'' |title=Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins. |journal=Genes Cells |volume=7 |issue= 12 |pages= 1231-42 |year= 2003 |pmid= 12485163 |doi=  }}
+*{{cite journal  | vauthors=Cheutin T, McNairn AJ, Jenuwein T |title=Maintenance of stable heterochromatin domains by dynamic HP1 binding |journal=Science |volume=299 |issue= 5607 |pages= 721–5 |year= 2003 |pmid= 12560555 |doi= 10.1126/science.1078572 |display-authors=etal}}
-*{{cite journal  | author=Cheutin T, McNairn AJ, Jenuwein T, ''et al.'' |title=Maintenance of stable heterochromatin domains by dynamic HP1 binding. |journal=Science |volume=299 |issue= 5607 |pages= 721-5 |year= 2003 |pmid= 12560555 |doi= 10.1126/science.1078572 }}
 }}
 {{refend}}
@@ Line 89: / Line 45: @@
 == External links ==
 * {{MeshName|CBX3+protein,+human}}
+* {{UCSC gene info|CBX3}}
-{{protein-stub}}
 {{NLM content}}
 {{Transcription factors}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
 [[Category:Transcription factors]]
-{{WikiDoc Sources}}

CBX3: Difference between revisions

Revision as of 09:14, 30 August 2017

Contents

Interactions

See also

References

Further reading

External links

Navigation menu