ATBF1: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Zinc finger homeobox protein 3''' is a [[protein]] that in humans is encoded by the ''ZFHX3'' [[gene]].<ref name="pmid1719379">{{cite journal | vauthors = Morinaga T, Yasuda H, Hashimoto T, Higashio K, Tamaoki T | title = A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers | journal = Mol Cell Biol | volume = 11 | issue = 12 | pages = 6041–9 |date=Dec 1991 | pmid = 1719379 | pmc = 361769 | doi = }}</ref><ref name="pmid7592926">{{cite journal | vauthors = Miura Y, Tam T, Ido A, Morinaga T, Miki T, Hashimoto T, Tamaoki T | title = Cloning and characterization of an ATBF1 isoform that expresses in a neuronal differentiation-dependent manner | journal = J Biol Chem | volume = 270 | issue = 45 | pages = 26840–8 |date=Dec 1995 | pmid = 7592926 | pmc =  | doi =10.1074/jbc.270.45.26840 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ATBF1 AT-binding transcription factor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=463| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = PBB_Protein_ATBF1_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 2da1.
| PDB = {{PDB2|2da1}}, {{PDB2|2da2}}, {{PDB2|2da3}}
| Name = AT-binding transcription factor 1
| HGNCid = 777
| Symbol = ATBF1
| AltSymbols =; ATBT; ZFHX3
| OMIM = 104155
| ECnumber = 
| Homologene = 21366
| MGIid = 99948
| GeneAtlas_image1 = PBB_GE_ATBF1_208033_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003705 |text = RNA polymerase II transcription factor activity, enhancer binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0043565 |text = sequence-specific DNA binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005622 |text = intracellular}} {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005739 |text = mitochondrion}}
| Process = {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0006366 |text = transcription from RNA polymerase II promoter}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 463
    | Hs_Ensembl = ENSG00000140836
    | Hs_RefseqProtein = NP_008816
    | Hs_RefseqmRNA = NM_006885
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 16
    | Hs_GenLoc_start = 71378464
    | Hs_GenLoc_end = 71639775
    | Hs_Uniprot = Q15911
    | Mm_EntrezGene = 11906
    | Mm_Ensembl = ENSMUSG00000038872
    | Mm_RefseqmRNA = NM_007496
    | Mm_RefseqProtein = NP_031522
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 8
    | Mm_GenLoc_start = 111603773
    | Mm_GenLoc_end = 111846367
    | Mm_Uniprot = Q5DTG5
  }}
}}
'''AT-binding transcription factor 1''', also known as '''ATBF1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ATBF1 AT-binding transcription factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=463| accessdate = }}</ref>
 
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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Morinaga T, Yasuda H, Hashimoto T, ''et al.'' |title=A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers. |journal=Mol. Cell. Biol. |volume=11 |issue= 12 |pages= 6041-9 |year= 1991 |pmid= 1719379 |doi=  }}
*{{cite journal  | vauthors=Yamada K, Miura Y, Scheidl T |title=Assignment of the human ATBF1 transcription factor gene to chromosome 16q22.3-q23.1 |journal=Genomics |volume=29 |issue= 2 |pages= 552–3 |year= 1996 |pmid= 8666409 |doi= 10.1006/geno.1995.9967 |display-authors=etal}}
*{{cite journal  | author=Miura Y, Tam T, Ido A, ''et al.'' |title=Cloning and characterization of an ATBF1 isoform that expresses in a neuronal differentiation-dependent manner. |journal=J. Biol. Chem. |volume=270 |issue= 45 |pages= 26840-8 |year= 1995 |pmid= 7592926 |doi=  }}
*{{cite journal  | vauthors=Bedford MT, Chan DC, Leder P |title=FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands |journal=EMBO J. |volume=16 |issue= 9 |pages= 2376–83 |year= 1997 |pmid= 9171351 |doi= 10.1093/emboj/16.9.2376 | pmc=1169838 }}
*{{cite journal  | author=Yamada K, Miura Y, Scheidl T, ''et al.'' |title=Assignment of the human ATBF1 transcription factor gene to chromosome 16q22.3-q23.1. |journal=Genomics |volume=29 |issue= 2 |pages= 552-3 |year= 1996 |pmid= 8666409 |doi= 10.1006/geno.1995.9967 }}
*{{cite journal  | vauthors=Kaspar P, Dvoráková M, Králová J |title=Myb-interacting protein, ATBF1, represses transcriptional activity of Myb oncoprotein |journal=J. Biol. Chem. |volume=274 |issue= 20 |pages= 14422–8 |year= 1999 |pmid= 10318867 |doi=10.1074/jbc.274.20.14422 |display-authors=etal}}
*{{cite journal  | author=Bedford MT, Chan DC, Leder P |title=FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands. |journal=EMBO J. |volume=16 |issue= 9 |pages= 2376-83 |year= 1997 |pmid= 9171351 |doi= 10.1093/emboj/16.9.2376 }}
*{{cite journal  | vauthors=Loftus BJ, Kim UJ, Sneddon VP |title=Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q |journal=Genomics |volume=60 |issue= 3 |pages= 295–308 |year= 1999 |pmid= 10493829 |doi= 10.1006/geno.1999.5927 |display-authors=etal}}
*{{cite journal  | author=Kaspar P, Dvoráková M, Králová J, ''et al.'' |title=Myb-interacting protein, ATBF1, represses transcriptional activity of Myb oncoprotein. |journal=J. Biol. Chem. |volume=274 |issue= 20 |pages= 14422-8 |year= 1999 |pmid= 10318867 |doi=  }}
*{{cite journal  | vauthors=Kaushik N, Malaspina A, de Belleroche J |title=Characterization of trinucleotide- and tandem repeat-containing transcripts obtained from human spinal cord cDNA library by high-density filter hybridization |journal=DNA Cell Biol. |volume=19 |issue= 5 |pages= 265–73 |year= 2000 |pmid= 10855793 |doi= 10.1089/10445490050021177 }}
*{{cite journal  | author=Loftus BJ, Kim UJ, Sneddon VP, ''et al.'' |title=Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. |journal=Genomics |volume=60 |issue= 3 |pages= 295-308 |year= 1999 |pmid= 10493829 |doi= 10.1006/geno.1999.5927 }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Kaushik N, Malaspina A, de Belleroche J |title=Characterization of trinucleotide- and tandem repeat-containing transcripts obtained from human spinal cord cDNA library by high-density filter hybridization. |journal=DNA Cell Biol. |volume=19 |issue= 5 |pages= 265-73 |year= 2000 |pmid= 10855793 |doi= 10.1089/10445490050021177 }}
*{{cite journal  | vauthors=Iida M, Imura J, Furuichi T |title=Alteration of the AT motif binding factor-1 expression in alpha-fetoprotein producing gastric cancer: is it an event for differentiation and proliferation of the tumors? |journal=Oncol. Rep. |volume=11 |issue= 1 |pages= 3–7 |year= 2004 |pmid= 14654895 |doi=  10.3892/or.11.1.3|display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Nojiri S, Joh T, Miura Y |title=ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3 |journal=Biochem. Biophys. Res. Commun. |volume=314 |issue= 1 |pages= 97–103 |year= 2004 |pmid= 14715251 |doi=10.1016/j.bbrc.2003.12.054 |display-authors=etal}}
*{{cite journal  | author=Iida M, Imura J, Furuichi T, ''et al.'' |title=Alteration of the AT motif binding factor-1 expression in alpha-fetoprotein producing gastric cancer: is it an event for differentiation and proliferation of the tumors? |journal=Oncol. Rep. |volume=11 |issue= 1 |pages= 3-7 |year= 2004 |pmid= 14654895 |doi=  }}
*{{cite journal  | vauthors=Martin J, Han C, Gordon LA |title=The sequence and analysis of duplication-rich human chromosome 16 |journal=Nature |volume=432 |issue= 7020 |pages= 988–94 |year= 2005 |pmid= 15616553 |doi= 10.1038/nature03187 |display-authors=etal}}
*{{cite journal  | author=Nojiri S, Joh T, Miura Y, ''et al.'' |title=ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3. |journal=Biochem. Biophys. Res. Commun. |volume=314 |issue= 1 |pages= 97-103 |year= 2004 |pmid= 14715251 |doi=  }}
*{{cite journal  | vauthors=Zhang Z, Yamashita H, Toyama T |title=ATBF1-a messenger RNA expression is correlated with better prognosis in breast cancer |journal=Clin. Cancer Res. |volume=11 |issue= 1 |pages= 193–8 |year= 2005 |pmid= 15671546 |doi=  |display-authors=etal}}
*{{cite journal  | author=Martin J, Han C, Gordon LA, ''et al.'' |title=The sequence and analysis of duplication-rich human chromosome 16. |journal=Nature |volume=432 |issue= 7020 |pages= 988-94 |year= 2005 |pmid= 15616553 |doi= 10.1038/nature03187 }}
*{{cite journal  | vauthors=Sun X, Frierson HF, Chen C |title=Frequent somatic mutations of the transcription factor ATBF1 in human prostate cancer |journal=Nat. Genet. |volume=37 |issue= 4 |pages= 407–12 |year= 2005 |pmid= 15750593 |doi= 10.1038/ng1528 |display-authors=etal}}
*{{cite journal  | author=Zhang Z, Yamashita H, Toyama T, ''et al.'' |title=ATBF1-a messenger RNA expression is correlated with better prognosis in breast cancer. |journal=Clin. Cancer Res. |volume=11 |issue= 1 |pages= 193-8 |year= 2005 |pmid= 15671546 |doi=  }}
*{{cite journal  | vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal}}
*{{cite journal  | author=Sun X, Frierson HF, Chen C, ''et al.'' |title=Frequent somatic mutations of the transcription factor ATBF1 in human prostate cancer. |journal=Nat. Genet. |volume=37 |issue= 4 |pages= 407-12 |year= 2005 |pmid= 15750593 |doi= 10.1038/ng1528 }}
*{{cite journal  | vauthors=Xu J, Sauvageot J, Ewing CM |title=Germline ATBF1 mutations and prostate cancer risk |journal=Prostate |volume=66 |issue= 10 |pages= 1082–5 |year= 2006 |pmid= 16637072 |doi= 10.1002/pros.20430 |display-authors=etal}}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal  | vauthors=Sun X, Zhou Y, Otto KB |title=Infrequent mutation of ATBF1 in human breast cancer |journal=J. Cancer Res. Clin. Oncol. |volume=133 |issue= 2 |pages= 103–5 |year= 2007 |pmid= 16932943 |doi= 10.1007/s00432-006-0148-y |display-authors=etal}}
*{{cite journal  | author=Xu J, Sauvageot J, Ewing CM, ''et al.'' |title=Germline ATBF1 mutations and prostate cancer risk. |journal=Prostate |volume=66 |issue= 10 |pages= 1082-5 |year= 2006 |pmid= 16637072 |doi= 10.1002/pros.20430 }}
*{{cite journal  | vauthors=Olsen JV, Blagoev B, Gnad F |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |display-authors=etal}}
*{{cite journal  | author=Sun X, Zhou Y, Otto KB, ''et al.'' |title=Infrequent mutation of ATBF1 in human breast cancer. |journal=J. Cancer Res. Clin. Oncol. |volume=133 |issue= 2 |pages= 103-5 |year= 2007 |pmid= 16932943 |doi= 10.1007/s00432-006-0148-y }}
*{{cite journal  | vauthors=Mori Y, Kataoka H, Miura Y |title=Subcellular localization of ATBF1 regulates MUC5AC transcription in gastric cancer |journal=Int. J. Cancer |volume=121 |issue= 2 |pages= 241–7 |year= 2007 |pmid= 17330845 |doi= 10.1002/ijc.22654 |display-authors=etal}}
*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal  | vauthors=Cho YG, Song JH, Kim CJ |title=Genetic alterations of the ATBF1 gene in gastric cancer |journal=Clin. Cancer Res. |volume=13 |issue= 15 Pt 1 |pages= 4355–9 |year= 2007 |pmid= 17671116 |doi= 10.1158/1078-0432.CCR-07-0619 |display-authors=etal}}
*{{cite journal  | author=Mori Y, Kataoka H, Miura Y, ''et al.'' |title=Subcellular localization of ATBF1 regulates MUC5AC transcription in gastric cancer. |journal=Int. J. Cancer |volume=121 |issue= 2 |pages= 241-7 |year= 2007 |pmid= 17330845 |doi= 10.1002/ijc.22654 }}
*{{cite journal  | author=Cho YG, Song JH, Kim CJ, ''et al.'' |title=Genetic alterations of the ATBF1 gene in gastric cancer. |journal=Clin. Cancer Res. |volume=13 |issue= 15 Pt 1 |pages= 4355-9 |year= 2007 |pmid= 17671116 |doi= 10.1158/1078-0432.CCR-07-0619 }}
}}
}}
{{refend}}
{{refend}}
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== External links ==
== External links ==
* {{MeshName|ATBF1+protein,+human}}
* {{MeshName|ATBF1+protein,+human}}
* {{UCSC gene info|ZFHX3}}


{{PDB Gallery|geneid=463}}
{{Transcription factors|g2}}
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{{protein-stub}}
{{Transcription factors}}
[[Category:Transcription factors]]
[[Category:Transcription factors]]
{{WikiDoc Sources}}
 
 
{{gene-16-stub}}

Latest revision as of 18:21, 29 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Zinc finger homeobox protein 3 is a protein that in humans is encoded by the ZFHX3 gene.[1][2][3]


References

  1. Morinaga T, Yasuda H, Hashimoto T, Higashio K, Tamaoki T (Dec 1991). "A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers". Mol Cell Biol. 11 (12): 6041–9. PMC 361769. PMID 1719379.
  2. Miura Y, Tam T, Ido A, Morinaga T, Miki T, Hashimoto T, Tamaoki T (Dec 1995). "Cloning and characterization of an ATBF1 isoform that expresses in a neuronal differentiation-dependent manner". J Biol Chem. 270 (45): 26840–8. doi:10.1074/jbc.270.45.26840. PMID 7592926.
  3. "Entrez Gene: ATBF1 AT-binding transcription factor 1".

Further reading

External links