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* {{cite journal | vauthors=Mahajan SS, Wilson AC |title=Mutations in host cell factor 1 separate its role in cell proliferation from recruitment of VP16 and LZIP. |journal=Mol. Cell. Biol. |volume=20 |issue= 3 |pages= 919–28 |year= 2000 |pmid= 10629049 |doi=10.1128/MCB.20.3.919-928.2000 | pmc=85209 }}
* {{cite journal | vauthors=Mahajan SS, Wilson AC |title=Mutations in host cell factor 1 separate its role in cell proliferation from recruitment of VP16 and LZIP. |journal=Mol. Cell. Biol. |volume=20 |issue= 3 |pages= 919–28 |year= 2000 |pmid= 10629049 |doi=10.1128/MCB.20.3.919-928.2000 | pmc=85209 }}
* {{cite journal | vauthors=Jin DY, Wang HL, Zhou Y |title=Hepatitis C virus core protein-induced loss of LZIP function correlates with cellular transformation. |journal=EMBO J. |volume=19 |issue= 4 |pages= 729–40 |year= 2000 |pmid= 10675342 |doi= 10.1093/emboj/19.4.729 | pmc=305611 |display-authors=etal}}
* {{cite journal | vauthors=Jin DY, Wang HL, Zhou Y |title=Hepatitis C virus core protein-induced loss of LZIP function correlates with cellular transformation. |journal=EMBO J. |volume=19 |issue= 4 |pages= 729–40 |year= 2000 |pmid= 10675342 |doi= 10.1093/emboj/19.4.729 | pmc=305611 |display-authors=etal}}
* {{cite journal | vauthors=Luciano RL, Wilson AC |title=N-terminal transcriptional activation domain of LZIP comprises two LxxLL motifs and the host cell factor-1 binding motif. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 20 |pages= 10757–62 |year= 2000 |pmid= 10984507 |doi= 10.1073/pnas.190062797 | pmc=27096 }}
* {{cite journal | vauthors=Luciano RL, Wilson AC |title=N-terminal transcriptional activation domain of LZIP comprises two LxxLL motifs and the host cell factor-1 binding motif. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 20 |pages= 10757–62 |year= 2000 |pmid= 10984507 |doi= 10.1073/pnas.190062797 | pmc=27096 |bibcode=2000PNAS...9710757L }}
* {{cite journal | vauthors=Raggo C, Rapin N, Stirling J |title=Luman, the cellular counterpart of herpes simplex virus VP16, is processed by regulated intramembrane proteolysis. |journal=Mol. Cell. Biol. |volume=22 |issue= 16 |pages= 5639–49 |year= 2002 |pmid= 12138176 |doi=10.1128/MCB.22.16.5639-5649.2002 | pmc=133973 |display-authors=etal}}
* {{cite journal | vauthors=Raggo C, Rapin N, Stirling J |title=Luman, the cellular counterpart of herpes simplex virus VP16, is processed by regulated intramembrane proteolysis. |journal=Mol. Cell. Biol. |volume=22 |issue= 16 |pages= 5639–49 |year= 2002 |pmid= 12138176 |doi=10.1128/MCB.22.16.5639-5649.2002 | pmc=133973 |display-authors=etal}}
* {{cite journal | vauthors=Mahajan SS, Little MM, Vazquez R, Wilson AC |title=Interaction of HCF-1 with a cellular nuclear export factor. |journal=J. Biol. Chem. |volume=277 |issue= 46 |pages= 44292–9 |year= 2003 |pmid= 12235138 |doi= 10.1074/jbc.M205440200 }}
* {{cite journal | vauthors=Mahajan SS, Little MM, Vazquez R, Wilson AC |title=Interaction of HCF-1 with a cellular nuclear export factor. |journal=J. Biol. Chem. |volume=277 |issue= 46 |pages= 44292–9 |year= 2003 |pmid= 12235138 |doi= 10.1074/jbc.M205440200 |pmc=4291127 }}
* {{cite journal | vauthors=Luciano RL, Wilson AC |title=An activation domain in the C-terminal subunit of HCF-1 is important for transactivation by VP16 and LZIP. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 21 |pages= 13403–8 |year= 2002 |pmid= 12271126 |doi= 10.1073/pnas.202200399 | pmc=129685 }}
* {{cite journal | vauthors=Luciano RL, Wilson AC |title=An activation domain in the C-terminal subunit of HCF-1 is important for transactivation by VP16 and LZIP. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 21 |pages= 13403–8 |year= 2002 |pmid= 12271126 |doi= 10.1073/pnas.202200399 | pmc=129685 |bibcode=2002PNAS...9913403L }}
* {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
* {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal|bibcode=2002PNAS...9916899M }}
* {{cite journal | vauthors=Ko J, Jang SW, Kim YS |title=Human LZIP binds to CCR1 and differentially affects the chemotactic activities of CCR1-dependent chemokines. |journal=FASEB J. |volume=18 |issue= 7 |pages= 890–2 |year= 2004 |pmid= 15001559 |doi= 10.1096/fj.03-0867fje |display-authors=etal}}
* {{cite journal | vauthors=Ko J, Jang SW, Kim YS |title=Human LZIP binds to CCR1 and differentially affects the chemotactic activities of CCR1-dependent chemokines. |journal=FASEB J. |volume=18 |issue= 7 |pages= 890–2 |year= 2004 |pmid= 15001559 |doi= 10.1096/fj.03-0867fje |display-authors=etal}}
* {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
* {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
* {{cite journal | vauthors=Misra V, Rapin N, Akhova O |title=Zhangfei is a potent and specific inhibitor of the host cell factor-binding transcription factor Luman. |journal=J. Biol. Chem. |volume=280 |issue= 15 |pages= 15257–66 |year= 2005 |pmid= 15705566 |doi= 10.1074/jbc.M500728200 |display-authors=etal}}
* {{cite journal | vauthors=Misra V, Rapin N, Akhova O |title=Zhangfei is a potent and specific inhibitor of the host cell factor-binding transcription factor Luman. |journal=J. Biol. Chem. |volume=280 |issue= 15 |pages= 15257–66 |year= 2005 |pmid= 15705566 |doi= 10.1074/jbc.M500728200 |display-authors=etal}}
* {{cite journal | vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal}}
* {{cite journal | vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal|bibcode=2005Natur.437.1173R }}
* {{cite journal | vauthors=Liang G, Audas TE, Li Y |title=Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element. |journal=Mol. Cell. Biol. |volume=26 |issue= 21 |pages= 7999–8010 |year= 2007 |pmid= 16940180 |doi= 10.1128/MCB.01046-06 | pmc=1636730 |display-authors=etal}}
* {{cite journal | vauthors=Liang G, Audas TE, Li Y |title=Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element. |journal=Mol. Cell. Biol. |volume=26 |issue= 21 |pages= 7999–8010 |year= 2007 |pmid= 16940180 |doi= 10.1128/MCB.01046-06 | pmc=1636730 |display-authors=etal}}
* {{cite journal | vauthors=Blot G, Lopez-Vergès S, Treand C |title=Luman, a new partner of HIV-1 TMgp41, interferes with Tat-mediated transcription of the HIV-1 LTR. |journal=J. Mol. Biol. |volume=364 |issue= 5 |pages= 1034–47 |year= 2007 |pmid= 17054986 |doi= 10.1016/j.jmb.2006.09.080 |display-authors=etal}}
* {{cite journal | vauthors=Blot G, Lopez-Vergès S, Treand C |title=Luman, a new partner of HIV-1 TMgp41, interferes with Tat-mediated transcription of the HIV-1 LTR. |journal=J. Mol. Biol. |volume=364 |issue= 5 |pages= 1034–47 |year= 2007 |pmid= 17054986 |doi= 10.1016/j.jmb.2006.09.080 |display-authors=etal}}

Revision as of 01:22, 23 June 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
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View/Edit Human

Cyclic AMP-responsive element-binding protein 3 is a protein that in humans is encoded by the CREB3 gene.[1][2]

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined.[2]

See also

Interactions

CREB3 has been shown to interact with Host cell factor C1.[3][4]

References

  1. Lu R, Yang P, O'Hare P, Misra V (Sep 1997). "Luman, a new member of the CREB/ATF family, binds to herpes simplex virus VP16-associated host cellular factor". Mol Cell Biol. 17 (9): 5117–26. PMC 232362. PMID 9271389.
  2. 2.0 2.1 "Entrez Gene: CREB3 cAMP responsive element binding protein 3".
  3. Lu, R; Yang P; Padmakumar S; Misra V (Aug 1998). "The herpesvirus transactivator VP16 mimics a human basic domain leucine zipper protein, luman, in its interaction with HCF". J. Virol. UNITED STATES. 72 (8): 6291–7. ISSN 0022-538X. PMC 109766. PMID 9658067.
  4. Freiman, R N; Herr W (Dec 1997). "Viral mimicry: common mode of association with HCF by VP16 and the cellular protein LZIP". Genes Dev. UNITED STATES. 11 (23): 3122–7. doi:10.1101/gad.11.23.3122. ISSN 0890-9369. PMC 316754. PMID 9389645.

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.